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Aox1  -  aldehyde oxidase 1

Rattus norvegicus

Synonyms: Aldehyde oxidase 1, Ao, Azaheterocycle hydroxylase 1
 
 
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Analytical, diagnostic and therapeutic context of Aox1

References

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  3. The aldehyde oxidase gene cluster in mice and rats. Aldehyde oxidase homologue 3, a novel member of the molybdo-flavoenzyme family with selective expression in the olfactory mucosa. Kurosaki, M., Terao, M., Barzago, M.M., Bastone, A., Bernardinello, D., Salmona, M., Garattini, E. J. Biol. Chem. (2004) [Pubmed]
  4. cDNA cloning, sequencing, and characterization of male and female rat liver aldehyde oxidase (rAOX1). Differences in redox status may distinguish male and female forms of hepatic APX. Wright, R.M., Clayton, D.A., Riley, M.G., McManaman, J.L., Repine, J.E. J. Biol. Chem. (1999) [Pubmed]
  5. TAO1, a representative of the molybdenum cofactor containing hydroxylases from tomato. Ori, N., Eshed, Y., Pinto, P., Paran, I., Zamir, D., Fluhr, R. J. Biol. Chem. (1997) [Pubmed]
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  9. Pharmacokinetics of the novel, high-affinity and selective dopamine D3 receptor antagonist SB-277011 in rat, dog and monkey: in vitro/in vivo correlation and the role of aldehyde oxidase. Austin, N.E., Baldwin, S.J., Cutler, L., Deeks, N., Kelly, P.J., Nash, M., Shardlow, C.E., Stemp, G., Thewlis, K., Ayrton, A., Jeffrey, P. Xenobiotica (2001) [Pubmed]
  10. Zebularine metabolism by aldehyde oxidase in hepatic cytosol from humans, monkeys, dogs, rats, and mice: influence of sex and inhibitors. Klecker, R.W., Cysyk, R.L., Collins, J.M. Bioorg. Med. Chem. (2006) [Pubmed]
  11. In vitro oxidation of pyrazinamide and allopurinol by rat liver aldehyde oxidase. Moriwaki, Y., Yamamoto, T., Nasako, Y., Takahashi, S., Suda, M., Hiroishi, K., Hada, T., Higashino, K. Biochem. Pharmacol. (1993) [Pubmed]
  12. Reduction of tertiary amine N-oxides by liver preparations: function of aldehyde oxidase as a major N-oxide reductase. Kitamura, S., Tatsumi, K. Biochem. Biophys. Res. Commun. (1984) [Pubmed]
  13. Subcellular localisation of guinea pig hepatic molybdenum hydroxylases. Critchley, D.J., Rance, D.J., Beedham, C. Biochem. Biophys. Res. Commun. (1992) [Pubmed]
  14. Immunohistochemical localization of aldehyde and xanthine oxidase in rat tissues using polyclonal antibodies. Moriwaki, Y., Yamamoto, T., Yamaguchi, K., Takahashi, S., Higashino, K. Histochem. Cell Biol. (1996) [Pubmed]
  15. Cytosolic xanthine oxidoreductase mediated bioactivation of ethanol to acetaldehyde and free radicals in rat breast tissue. Its potential role in alcohol-promoted mammary cancer. Castro, G.D., Delgado de Layño, A.M., Costantini, M.H., Castro, J.A. Toxicology (2001) [Pubmed]
  16. 5-ethynyl-2(1H)-pyrimidinone: aldehyde oxidase-activation to 5-ethynyluracil, a mechanism-based inactivator of dihydropyrimidine dehydrogenase. Porter, D.J., Harrington, J.A., Almond, M.R., Lowen, G.T., Zimmerman, T.P., Spector, T. Biochem. Pharmacol. (1994) [Pubmed]
  17. In vivo pharmacokinetics and regulation of gene expression profiles by isothiocyanate sulforaphane in the rat. Hu, R., Hebbar, V., Kim, B.R., Chen, C., Winnik, B., Buckley, B., Soteropoulos, P., Tolias, P., Hart, R.P., Kong, A.N. J. Pharmacol. Exp. Ther. (2004) [Pubmed]
  18. Transamination in the metabolism of the nephrotoxicant N-(3,5-dichlorophenyl)succinimide in rats. Cui, D., Rankin, G.O., Harvison, P.J. Drug Metab. Dispos. (2005) [Pubmed]
  19. Activities of cytosolic and microsomal drug oxidases of rat hepatocytes in primary culture. Sherratt, A.J., Damani, L.A. Drug Metab. Dispos. (1989) [Pubmed]
  20. Iron deficiency in the rat: biochemical studies of brain metabolism. Mackler, B., Person, R., Miller, L.R., Inamdar, A.R., Finch, C.A. Pediatr. Res. (1978) [Pubmed]
  21. Metabolism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in perfused rat liver: involvement of hepatic aldehyde oxidase as a detoxification enzyme. Yoshihara, S., Harada, K., Ohta, S. Drug Metab. Dispos. (2000) [Pubmed]
  22. Cynomolgus monkey liver aldehyde oxidase: extremely high oxidase activity and an attempt at purification. Sugihara, K., Katsuma, Y., Kitamura, S., Ohta, S., Fujitani, M., Shintani, H. Comp. Biochem. Physiol. C Toxicol. Pharmacol. (2000) [Pubmed]
 
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