Disease relevance of GARNL1

• X-ray crystallographic coordinates of influenza virus N9 neuraminidase complexed with monoclonal antibodies NC41 and NC10 [Tulip et al. (1992) J. Mol. Biol. 227, 122-148] served as a starting point for calculations aimed at estimating free energy changes (delta G) of complex formation between the two antibodies and the neuraminidase [1].
• CONCLUSIONS: Cephalic migration of a clotted temporary IVC filter can be managed with intraprocedural protection against pulmonary embolism by first deploying a Günther Tulip filter above the renal veins, with subsequent advancement below the renal veins before temporary filter removal [2].
• A Günther Tulip inferior vena cava (IVC) filter was placed prophylactically in a 22-year-old trauma victim with spinal injuries [3].
• RESULTS: The in-vitro embolus capturing efficiency of the Celect filter proved to be equivalent to the Tulip filter [4].
• Placement of a retrievable Günther Tulip filter in the superior vena cava for upper extremity deep venous thrombosis [5].

High impact information on GARNL1

• The three-dimensional structure of one of these epitopes, recognized by monoclonal antibody NC41, has previously been determined (W. R. Tulip, J. N. Varghese, R. G. Webster, G. M. Air, W. G. Laver, and P. M. Colman, Cold Spring Harbor Symp. Quant. Biol. 54:257-263, 1989) [6].
• The human TULIP1 gene was mapped to chromosome band 14q13.2 by fluorescence in situ hybridization of BAC clone RP11-355C3 (GenBank Accession No. AL160231), containing the 3' region of the gene [7].
• An untranscribed, processed pseudogene of TULIP1 was found on human chromosome band 9q31 [7].
• Cloning, genomic structure, and expression profiles of TULIP1 (GARNL1), a brain-expressed candidate gene for 14q13-linked neurological phenotypes, and its murine homologue [7].
• TULIP1 spans about 271 kb of human genomic DNA and is divided into 41 exons [7].

Biological context of GARNL1

• Günther Tulip Retrievable Vena Cava Filter: results from the Registry of the Canadian Interventional Radiology Association [8].

Anatomical context of GARNL1

• PURPOSE: To evaluate the safety and effectiveness of retrieval of the Günther Tulip inferior vena cava (IVC) filter [9].
• CONCLUSION: In this multicenter study, retrieval of the Günther Tulip filter was safe and without recurrent thromboembolic events or evidence of IVC or jugular vein damage at 3-month follow-up [9].
• Removal of Günther Tulip vena cava filter through femoral vein approach [10].
• A Günther Tulip retrievable inferior vena cava filter was placed in a 9-year-old boy with T-cell ALL who had both iliofemoral deep vein thrombosis (DVT) and acute intracranial hemorrhage [11].

Associations of GARNL1 with chemical compounds

• Medium clots were effectively captured by Bird's Nest, Simon nitinol, Antheor, and Günther Tulip filters (79%-100%) [12].
• MATERIALS AND METHODS: Three filters, the titanium Greenfield, Vena Tech-LGM, and Günther Tulip retrievable, were studied with use of 20- or 26-mm-diameter tubes to simulate the inferior vena cava [13].

Analytical, diagnostic and therapeutic context of GARNL1

• PURPOSE: To report on the feasibility and safety of retrieval of the G??nther Tulip optional vena cava filter 30 days after initial implantation [14].
• Günther Tulip filter retrievability multicenter study including CT follow-up: final report [9].
• The Günther Tulip retrievable filter: prolonged temporary filtration by repositioning within the inferior vena cava [15].
• The mean absolute differences between MR and fluoroscopy were 0.088 mm for the OptEase filter, 0.41 mm for the Bard Recovery filter, and 0.34 mm for the Günther Tulip filter [16].
• A 79-year-old woman was diagnosed as right femoral vein thrombosis, and a retrievable Günther Tulip filter was deployed prior to a total knee replacement surgery [17].

References