Disease relevance of Nitinol

• To define the clinical value of this technique, we prospectively studied the use of stent-graft endoprostheses made of nitinol and covered with polyester fabric for the treatment of infrarenal abdominal aortic aneurysms [1].
• Stainless steel stents at 4 days contained more thrombus than 4- and 14-day nitinol stents (20.0 +/- 5.9 versus 2.5 +/- 0.6 and 2.7 +/- 0.3 mg, respectively; P < .000001) [2].
• Transvenous closure of secundum atrial septal defects: preliminary results with a new self-expanding nitinol prosthesis in a swine model [3].
• METHODS: Seventy-three symptomatic patients (58 men; mean age 67 years) were treated with nitinol stents for lesions in the iliac artery (9 stenoses); superficial femoral artery (SFA) (39 stenoses, 6 occlusions); popliteal artery and tibioperoneal trunk (9 stenoses, 7 occlusions); and 3 bypass grafts [4].
• Palliation of malignant esophageal strictures with self-expanding nitinol stents: drawbacks and complications [5].

High impact information on Nitinol

• CONCLUSIONS: Slotted-tube stainless steel stents were more thrombogenic and created more extensive vascular injury than nitinol stents in a rabbit carotid artery model [2].
• Stainless steel stents were more often occluded by thrombus (6 of 8) or contained more subocclusive thrombus (2 of 8) than nitinol stents (0 of 14, P < .002) [2].
• Seventy-eight stents constructed from the shape-memory nickel-titanium alloy nitinol were deployed by balloon expansion in the coronary arteries of 28 dogs and left in place for up to 6 months [6].
• The device, made of a Nitinol and polyester fabric mesh, provides a different approach to defect occlusion by stenting the atrial septal defect up to a stretched diameter of 26 mm [7].
• CONCLUSIONS: This new nitinol stent seems to be safe and effective with favorable long-term results, even in distal SFA lesions and popliteal arteries [4].

Chemical compound and disease context of Nitinol

• The double umbrella-like occlusion device is made from nitinol mesh and closes luminal contact between the esophageal and bronchial walls, with its waist filling out the fistula itself [8].
• Use of histoacryl and a covered nitinol stent to treat a bronchobiliary fistula [9].
• In torsion not even the largest sizes of nickel-titanium (0.021 by 0.025 inch) or beta titanium (0.019 by 0.025 inch) wire meet the stiffness requirements of an 0.019 by 0.026 inch stainless steel wire, thereby making the established alloys the finishing wire of choice [10].
• Adjuncts to reduce scope damage during these procedures were the use of the ureteral access sheath (n = 109), nitinol devices allowing lower pole stone retrieval (n = 27), and the 200-microm holmium laser fiber for stone fragmentation, tumor ablation, and incision of ureteropelvic junction/ureteral stenoses (n = 91) [11].
• Efficacy of a dexamethasone-eluting nitinol stent on the inhibition of pseudo-intimal hyperplasia in a transjugular intrahepatic portosystemic shunt: an experimental study in a swine model [12].

Biological context of Nitinol

• Each ureteroscope was evaluated with an empty working channel, and then with sheathed and unsheathed 2.2, 3 and 3.2Fr (Cook Urological, Inc., Indianapolis, Indiana), 2.4 and 3Fr (Microvasive Urology, Natick, Massachusetts) nitinol baskets in the working channel [13].
• Nitinol is potentially very useful in orthopedic surgery, for example [14].
• Effect of nickel-titanium shape memory metal alloy on bone formation [15].
• Despite the higher initial nickel dissolution, Nitinol induced no toxic effects, decrease in cell proliferation, or inhibition on the growth of cells in contact with the metal surface [14].
• Nitinol properties affecting uses in interventional radiology [16].

Anatomical context of Nitinol

• BACKGROUND: Our objectives were to quantify the thrombogenicity and extent of vascular injury created by slotted-tube geometry stainless steel and nitinol coronary stents in a rabbit carotid artery model [2].
• This study demonstrates the feasibility of a new method of temporary stenting that uses the thermoelastic properties of nitinol to permit reliable recovery of the stent in normal canine coronary arteries [6].
• PURPOSE: To determine the effectiveness of a prototype nitinol stent in the iliac arteries [17].
• MATERIALS AND METHODS: A composite nitinol-collagen endovascular stent-graft with a 4-mm inner diameter was deployed in the abdominal aorta in nine rabbits [18].
• MATERIALS AND METHODS: Polyurethane-covered retrievable 0.10-mm-thick (n = 11) or 0.15-mm-thick (n = 10) nitinol wire stents were placed in the urethras of 20 dogs [19].

Associations of Nitinol with other chemical compounds

• CONCLUSION: Although some design modifications are necessary to reduce current complications, the polyurethane-covered retrievable nitinol stent seems feasible for use in the urethra [19].
• Magnetic resonance (MR) images and radiographs of ABI alloy and stainless steel 316 stent models and of nitinol, tantalum, and Elgiloy stents were compared [20].
• CONCLUSION: Polyethylene terephthalate-coated nitinol stents showed good biocompatibility and a high rate of occlusion of experimental AVFs [21].
• MATERIALS AND METHODS: Four prosthesis types--two Dacron-covered nitinol stent-grafts (plain and heparin-coated) and two noncovered nitinol stents (Memotherm and Cragg)--were each inserted into the external iliac arteries of eight sheep [22].
• CONCLUSIONS: A temperature activated, deflectable nitinol sheath facilitates active deflection with a 272 mum holmium laser fiber in the working channel of the flexible ureteroscope, suggesting strong potential for clinical evaluation [23].

Gene context of Nitinol

• We conclude that a rough NiTi surface promotes TGF-beta1 expression in ROS-17/2.8 cells [24].
• RESULTS: Image artifacts produced by the nitinol framework in these endoprostheses were minimal when fast spin-echo or spin-echo imaging techniques were used, improving the visibility of the device [25].
• Simon nitinol inferior vena cava filter: initial clinical experience. Work in progress [26].
• MATERIALS AND METHODS: A self-expanding endoprosthesis with an expanded polytetrafluoroethylene tube inside a nitinol support structure was implanted in 127 patients with symptomatic PAOD in the iliac (61 limbs) and femoral arteries (80 limbs) [27].
• Coated polyester prostheses (Hemashield; Boston Scientific Corporation, Boston, Mass) were used in the OS patients, whereas a modular nitinol polyester device (AneuRx; Medtronic, Sunnyvale, Calif) was used in the ES group [28].

Analytical, diagnostic and therapeutic context of Nitinol

• Nitinol stents (2 mum in diameter, n = 120) were placed in a tubular chamber and perfused with blood from pigs (n = 13) at a shear rate of 2100s-1 for 20 minutes [29].
• The self-expanding prosthesis was braided from 0.005-in Nitinol wires in the shape of two flat buttons with a short connecting waist with a diameter corresponding to that of the defect to be closed [3].
• The Symmetry Bypass Connector (St. Jude Medical, St. Paul, Minnesota) is a nitinol, star-shaped device that was designed to facilitate placement of sutureless aorto-saphenous anastomoses during off-pump coronary artery bypass graft surgery (CABG) [30].
• Eleven patients implanted with a bare nitinol stent served as the control group [31].
• MATERIALS AND METHODS: Contrast material-enhanced MR imaging was performed in 14 patients with polyester-covered nitinol stents, 10 patients with conventional metallic stents, and 12 patients who underwent peripheral percutaneous transluminal angioplasty [32].

References