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Gene Review

GJB1  -  gap junction protein, beta 1, 32kDa

Bos taurus

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High impact information on GJB1


Anatomical context of GJB1


Associations of GJB1 with chemical compounds


Analytical, diagnostic and therapeutic context of GJB1

  • Western blot analysis also showed the decrease of Cx32 protein levels by H2O2 treatment, which decrease was prevented by taurine [6].
  • Steady state mRNA levels of Cx32 were detected by Northern blotting [6].
  • Immunofluorescence analysis for Cx32 demonstrated numerous punctate fluorescent spots along the intercellular plasma membrane in controls, which were significantly decreased by H2O2 [6].


  1. Dynamic changes of gap junctions and cytoskeleton during in vitro culture of cattle oocyte cumulus complexes. Sutovský, P., Fléchon, J.E., Fléchon, B., Motlik, J., Peynot, N., Chesné, P., Heyman, Y. Biol. Reprod. (1993) [Pubmed]
  2. Expression of gap junctional connexins 26, 32 and 43 in bovine placentomes during pregnancy. Pfarrer, C.D., Heeb, C., Leiser, R. Placenta (2006) [Pubmed]
  3. Growth and maturation of small hepatocytes isolated from adult rat liver. Mitaka, T., Kojima, T., Mizuguchi, T., Mochizuki, Y. Biochem. Biophys. Res. Commun. (1995) [Pubmed]
  4. Gap junctional intercellular communication of bovine granulosa and thecal cells from antral follicles: effects of luteinizing hormone and follicle-stimulating hormone. Johnson, M.L., Redmer, D.A., Reynolds, L.P., Bilski, J.J., Grazul-Bilska, A.T. Endocrine (2002) [Pubmed]
  5. Expression of gap junctional proteins connexin 43, 32, and 26 throughout follicular development and atresia in cows. Johnson, M.L., Redmer, D.A., Reynolds, L.P., Grazul-Bilska, A.T. Endocrine (1999) [Pubmed]
  6. Taurine preserves gap junctional intercellular communication in rat hepatocytes under oxidative stress. Fukuda, T., Ikejima, K., Hirose, M., Takei, Y., Watanabe, S., Sato, N. J. Gastroenterol. (2000) [Pubmed]
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