Gene Review:
esc - extra sexcombs
Drosophila melanogaster
Synonyms:
CG14941, Dmel\CG14941, ESC, Esc, L41867, ...
- Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites. Czermin, B., Melfi, R., McCabe, D., Seitz, V., Imhof, A., Pirrotta, V. Cell (2002)
- Early role of the esc+ gene product in the determination of segments in Drosophila. Struhl, G., Brower, D. Cell (1982)
- A gene product required for correct initiation of segmental determination in Drosophila. Struhl, G. Nature (1981)
- The Polycomb-group gene, extra sex combs, encodes a nuclear member of the WD-40 repeat family. Gutjahr, T., Frei, E., Spicer, C., Baumgartner, S., White, R.A., Noll, M. EMBO J. (1995)
- Alternative ESC and ESC-like subunits of a polycomb group histone methyltransferase complex are differentially deployed during Drosophila development. Wang, L., Jahren, N., Vargas, M.L., Andersen, E.F., Benes, J., Zhang, J., Miller, E.L., Jones, R.S., Simon, J.A. Mol. Cell. Biol. (2006)
- The Drosophila Polycomb Group proteins ESC and E(Z) are present in a complex containing the histone-binding protein p55 and the histone deacetylase RPD3. Tie, F., Furuyama, T., Prasad-Sinha, J., Jane, E., Harte, P.J. Development (2001)
- Interactions of polyhomeotic with Polycomb group genes of Drosophila melanogaster. Cheng, N.N., Sinclair, D.A., Campbell, R.B., Brock, H.W. Genetics (1994)
- A Drosophila ESC-E(Z) protein complex is distinct from other polycomb group complexes and contains covalently modified ESC. Ng, J., Hart, C.M., Morgan, K., Simon, J.A. Mol. Cell. Biol. (2000)
- Participation of Polycomb group gene extra sex combs in hedgehog signaling pathway. Shindo, N., Sakai, A., Yamada, K., Higashinakagawa, T. Biochem. Biophys. Res. Commun. (2004)
- A 1-megadalton ESC/E(Z) complex from Drosophila that contains polycomblike and RPD3. Tie, F., Prasad-Sinha, J., Birve, A., Rasmuson-Lestander, A., Harte, P.J. Mol. Cell. Biol. (2003)
- Mutations in the extra sex combs and Enhancer of Polycomb Genes Increase Homologous Recombination in Somatic Cells of Drosophila melanogaster. Holmes, A.M., Weedmark, K.A., Gloor, G.B. Genetics (2006)
- Mutations in some Polycomb group genes of Drosophila interfere with regulation of segmentation genes. McKeon, J., Slade, E., Sinclair, D.A., Cheng, N., Couling, M., Brock, H.W. Mol. Gen. Genet. (1994)
- Effects of Polycomb group mutations on the expression of Ultrabithorax in the Drosophila visceral mesoderm. Choi, S.H., Oh, C.T., Kim, S.H., Kim, Y.T., Jeon, S.H. Mol. Cells (2000)
- Genetic interactions and dosage effects of Polycomb group genes of Drosophila. Campbell, R.B., Sinclair, D.A., Couling, M., Brock, H.W. Mol. Gen. Genet. (1995)
- Polycomblike PHD fingers mediate conserved interaction with enhancer of zeste protein. O'Connell, S., Wang, L., Robert, S., Jones, C.A., Saint, R., Jones, R.S. J. Biol. Chem. (2001)
- Evolutionary conservation and predicted structure of the Drosophila extra sex combs repressor protein. Ng, J., Li, R., Morgan, K., Simon, J. Mol. Cell. Biol. (1997)
- The Drosophila Polycomb Group proteins ESC and E(Z) bind directly to each other and co-localize at multiple chromosomal sites. Tie, F., Furuyama, T., Harte, P.J. Development (1998)