The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Gene Review

PTGS1  -  prostaglandin-endoperoxide synthase 1...

Ovis aries

Synonyms: COX-1, COX1, PGHS-1
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of PTGS1

 

High impact information on PTGS1

 

Biological context of PTGS1

 

Anatomical context of PTGS1

 

Associations of PTGS1 with chemical compounds

 

Other interactions of PTGS1

 

Analytical, diagnostic and therapeutic context of PTGS1

References

  1. The expression of cytosolic phospholipase A2 and prostaglandin endoperoxide synthase in ovine maternal uterine and fetal tissues during late gestation and labor. Zhang, Q., Wu, W.X., Brenna, J.T., Nathanielsz, P.W. Endocrinology (1996) [Pubmed]
  2. PIOX, a new pathogen-induced oxygenase with homology to animal cyclooxygenase. Sanz, A., Moreno, J.I., Castresana, C. Plant Cell (1998) [Pubmed]
  3. Reaction of prostaglandin endoperoxide synthase with cis,cis-eicosa-11,14-dienoic acid. Koshkin, V., Dunford, H.B. J. Biol. Chem. (1998) [Pubmed]
  4. Investigation of the role of cysteines in catalysis by prostaglandin endoperoxide synthase. Kennedy, T.A., Smith, C.J., Marnett, L.J. J. Biol. Chem. (1994) [Pubmed]
  5. Prostaglandin endoperoxide synthase substituted with manganese protoporphyrin IX. Formation of a higher oxidation state and its relation to cyclooxygenase reaction. Strieder, S., Schaible, K., Scherer, H.J., Dietz, R., Ruf, H.H. J. Biol. Chem. (1992) [Pubmed]
  6. Tyrosine 385 of prostaglandin endoperoxide synthase is required for cyclooxygenase catalysis. Shimokawa, T., Kulmacz, R.J., DeWitt, D.L., Smith, W.L. J. Biol. Chem. (1990) [Pubmed]
  7. Primary structure of sheep prostaglandin endoperoxide synthase deduced from cDNA sequence. Yokoyama, C., Takai, T., Tanabe, T. FEBS Lett. (1988) [Pubmed]
  8. Orientation of the active site and antigenic determinants of prostaglandin endoperoxide synthase in the endoplasmic reticulum. DeWitt, D.L., Rollins, T.E., Day, J.S., Gauger, J.A., Smith, W.L. J. Biol. Chem. (1981) [Pubmed]
  9. The expression of prostaglandin endoperoxide synthase 2 messenger RNA and the proportion of smooth muscle and collagen in the sheep cervix during the estrous cycle. Kershaw, C.M., Scaramuzzi, R.J., McGowan, M.R., Wheeler-Jones, C.P., Khalid, M. Biol. Reprod. (2007) [Pubmed]
  10. Cellular source in ewes of prostaglandin-endoperoxide synthase-2 in uterine arteries following stimulation with lipopolysaccharide. Vagnoni, K.E., Christiansen, N.D., Holyoak, G.R., Janowiak, M.A., Martin, P.H. Biol. Reprod. (1999) [Pubmed]
  11. Isolation and characterization of the complementary DNA for sheep seminal vesicle prostaglandin endoperoxide synthase (cyclooxygenase). Merlie, J.P., Fagan, D., Mudd, J., Needleman, P. J. Biol. Chem. (1988) [Pubmed]
  12. Oxygenation of 5,8,11-eicosatrienoic acid by prostaglandin endoperoxide synthase and by cytochrome P450 monooxygenase: structure and mechanism of formation of major metabolites. Oliw, E.H., Hörnsten, L., Sprecher, H., Hamberg, M. Arch. Biochem. Biophys. (1993) [Pubmed]
  13. Ontogeny of immunoreactive prostaglandin endoperoxide synthase isoforms in ovine fetal pituitary, hypothalamus and brainstem. Deauseault, D., Giroux, D., Wood, C.E. Neuroendocrinology (2000) [Pubmed]
  14. Differential modification of cyclo-oxygenase and peroxidase activities of prostaglandin endoperoxidase synthase by proteolytic digestion and hydroperoxides. Raz, A., Needleman, P. Biochem. J. (1990) [Pubmed]
  15. Inactivation of prostaglandin endoperoxide synthase by acylating derivatives of indomethacin. Wells, I., Marnett, L.J. Biochemistry (1993) [Pubmed]
  16. A free radical mediated cooxidation of tetramethylhydrazine by prostaglandin hydroperoxidase. Kalyanaraman, B., Sivarajah, K., Eling, T.E., Mason, R.P. Carcinogenesis (1983) [Pubmed]
  17. Mechanism of hydroperoxide reduction by mangano-prostaglandin endoperoxide synthase. Landino, L.M., Marnett, L.J. Biochemistry (1996) [Pubmed]
  18. Prostaglandin endoperoxide synthase-2 abundance is increased in brain tissues of late-gestation fetal sheep in response to cerebral hypoperfusion. Tong, H., Richards, E., Wood, C.E. J. Soc. Gynecol. Investig. (1999) [Pubmed]
  19. In situ hybridization analysis of ovarian prostaglandin endoperoxide synthase mRNA throughout the periovulatory period of the ewe. Murdoch, W.J., Slaughter, R.G., Ji, T.H. Domest. Anim. Endocrinol. (1991) [Pubmed]
 
WikiGenes - Universities