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Gene Review

CFC1  -  cripto, FRL-1, cryptic family 1

Homo sapiens

Synonyms: CFC1B, CRYPTIC, Cryptic family protein 1, Cryptic protein, DTGA2, ...
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Disease relevance of CFC1


Psychiatry related information on CFC1


High impact information on CFC1


Biological context of CFC1


Associations of CFC1 with chemical compounds


Other interactions of CFC1


  1. CFC1 mutations in patients with transposition of the great arteries and double-outlet right ventricle. Goldmuntz, E., Bamford, R., Karkera, J.D., dela Cruz, J., Roessler, E., Muenke, M. Am. J. Hum. Genet. (2002) [Pubmed]
  2. Mutations in the EGF-CFC Gene Cryptic Are an Infrequent Cause of Congenital Heart Disease. Ozcelik, C., Bit-Avragim, N., Panek, A., Gaio, U., Geier, C., Lange, P.E., Dietz, R., Posch, M.G., Perrot, A., Stiller, B. Pediatric cardiology (2006) [Pubmed]
  3. Inhibition of Experimental Metastasis by Targeting the HUIV26 Cryptic Epitope in Collagen. Roth, J.M., Caunt, M., Cretu, A., Akalu, A., Policarpio, D., Li, X., Gagne, P., Formenti, S., Brooks, P.C. Am. J. Pathol. (2006) [Pubmed]
  4. Analysis of Core Housekeeping and Virulence Genes Reveals Cryptic Lineages of Clostridium perfringens That Are Associated With Distinct Disease Presentations. Rooney, A.P., Swezey, J.L., Friedman, R., Hecht, D.W., Maddox, C.W. Genetics (2006) [Pubmed]
  5. The evolutionary biology of cryptic pregnancy: A re-appraisal of the "denied pregnancy" phenomenon. Del Giudice, M. Med. Hypotheses (2007) [Pubmed]
  6. V(D)J Recombinase-Mediated Processing of Coding Junctions at Cryptic Recombination Signal Sequences in Peripheral T Cells during Human Development. Murray, J.M., O'neill, J.P., Messier, T., Rivers, J., Walker, V.E., McGonagle, B., Trombley, L., Cowell, L.G., Kelsoe, G., McBlane, F., Finette, B.A. J. Immunol. (2006) [Pubmed]
  7. Terminal 22q deletion syndrome: a newly recognized cause of speech and language disability in the autism spectrum. Manning, M.A., Cassidy, S.B., Clericuzio, C., Cherry, A.M., Schwartz, S., Hudgins, L., Enns, G.M., Hoyme, H.E. Pediatrics (2004) [Pubmed]
  8. Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects. Bamford, R.N., Roessler, E., Burdine, R.D., Saplakoğlu, U., dela Cruz, J., Splitt, M., Goodship, J.A., Towbin, J., Bowers, P., Ferrero, G.B., Marino, B., Schier, A.F., Shen, M.M., Muenke, M., Casey, B. Nat. Genet. (2000) [Pubmed]
  9. Computational Sampling of a Cryptic Drug Binding Site in a Protein Receptor: Explicit Solvent Molecular Dynamics and Inhibitor Docking to p38 MAP Kinase. Frembgen-Kesner, T., Elcock, A.H. J. Mol. Biol. (2006) [Pubmed]
  10. The Major Histocompatibility Complex Haplotypes Dictate and the Background Genes Fine-tune the Dominant versus the Cryptic Response Profile of a T-cell Determinant within a Native Antigen: Relevance to Disease Susceptibility and Vaccination. Sinha, P., Snyder, J.A., Kim, E.Y., Moudgil, K.D. Scand. J. Immunol. (2007) [Pubmed]
  11. Dermatofibrosarcoma protuberans: report of a case with a variant ring chromosome and metastases following pregnancy. Bigby, S.M., Oei, P., Lambie, N.K., Symmans, P.J. J. Cutan. Pathol. (2006) [Pubmed]
  12. Morphological and Genetic Variation Indicate Cryptic Species Within Lamarck's Little Sea Star, Parvulastra (=Patiriella) exigua. Hart, M.W., Keever, C.C., Dartnall, A.J., Byrne, M. Biol. Bull. (2006) [Pubmed]
  13. Maize Ear Rot and Moniliformin Contamination by Cryptic Species of Fusarium subglutinans. Desjardins, A.E., Maragos, C.M., Proctor, R.H. J. Agric. Food Chem. (2006) [Pubmed]
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