Gene Review:
BNIP2 - BCL2/adenovirus E1B 19kDa interacting...
Homo sapiens
Synonyms:
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2, BNIP-2, NIP2, Nip2
- Tyrosine phosphorylation of the Bcl-2-associated protein BNIP-2 by fibroblast growth factor receptor-1 prevents its binding to Cdc42GAP and Cdc42. Low, B.C., Lim, Y.P., Lim, J., Wong, E.S., Guy, G.R. J. Biol. Chem. (1999)
- Molecular profiling of mouse lung tumors: association with tumor progression, lung development, and human lung adenocarcinomas. Bonner, A.E., Lemon, W.J., Devereux, T.R., Lubet, R.A., You, M. Oncogene (2004)
- Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins. Boyd, J.M., Malstrom, S., Subramanian, T., Venkatesh, L.K., Schaeper, U., Elangovan, B., D'Sa-Eipper, C., Chinnadurai, G. Cell (1994)
- Estrogen and progesterone induction of survival of monoblastoid cells undergoing TNF-alpha-induced apoptosis. Vegeto, E., Pollio, G., Pellicciari, C., Maggi, A. FASEB J. (1999)
- Identification of estrogen-responsive genes in neuroblastoma SK-ER3 cells. Garnier, M., Di Lorenzo, D., Albertini, A., Maggi, A. J. Neurosci. (1997)
- The BNIP-2 and Cdc42GAP homology/Sec14p-like domain of BNIP-Salpha is a novel apoptosis-inducing sequence. Zhou, Y.T., Soh, U.J., Shang, X., Guy, G.R., Low, B.C. J. Biol. Chem. (2002)
- Estrogen neuroprotection: the involvement of the Bcl-2 binding protein BNIP2. Belcredito, S., Vegeto, E., Brusadelli, A., Ghisletti, S., Mussi, P., Ciana, P., Maggi, A. Brain Res. Brain Res. Rev. (2001)
- BNIPL-2, a novel homologue of BNIP-2, interacts with Bcl-2 and Cdc42GAP in apoptosis. Qin, W., Hu, J., Guo, M., Xu, J., Li, J., Yao, G., Zhou, X., Jiang, H., Zhang, P., Shen, L., Wan, D., Gu, J. Biochem. Biophys. Res. Commun. (2003)
- Evidence for a novel Cdc42GAP domain at the carboxyl terminus of BNIP-2. Low, B.C., Seow, K.T., Guy, G.R. J. Biol. Chem. (2000)
- BNIP-2 induces cell elongation and membrane protrusions by interacting with Cdc42 via a unique Cdc42-binding motif within its BNIP-2 and Cdc42GAP homology domain. Zhou, Y.T., Guy, G.R., Low, B.C. Exp. Cell Res. (2005)
- The BNIP-2 and Cdc42GAP homology domain of BNIP-2 mediates its homophilic association and heterophilic interaction with Cdc42GAP. Low, B.C., Seow, K.T., Guy, G.R. J. Biol. Chem. (2000)
- Increased expression of proapoptotic BMCC1, a novel gene with the BNIP2 and Cdc42GAP homology (BCH) domain, is associated with favorable prognosis in human neuroblastomas. Machida, T., Fujita, T., Ooo, M.L., Ohira, M., Isogai, E., Mihara, M., Hirato, J., Tomotsune, D., Hirata, T., Fujimori, M., Adachi, W., Nakagawara, A. Oncogene (2006)
- BNIP-Salpha induces cell rounding and apoptosis by displacing p50RhoGAP and facilitating RhoA activation via its unique motifs in the BNIP-2 and Cdc42GAP homology domain. Zhou, Y.T., Guy, G.R., Low, B.C. Oncogene (2006)
- The apoptosis-associated protein BNIPL interacts with two cell proliferation-related proteins, MIF and GFER. Shen, L., Hu, J., Lu, H., Wu, M., Qin, W., Wan, D., Li, Y.Y., Gu, J. FEBS Lett. (2003)