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JADE1  -  jade family PHD finger 1

Homo sapiens

Synonyms: JADE-1, Jade family PHD finger protein 1, KIAA1807, PHD finger protein 17, PHF17, ...
 
 
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Disease relevance of PHF17

 

Psychiatry related information on PHF17

  • The fluorescent agent Fluoro Jade was applied to cortical brain sections obtained from human patients at early postnatal ages and in patients with Alzheimer's disease, and from a Cebus apella monkey after mechanical lesioning of the cerebral cortex [5].
 

High impact information on PHF17

 

Chemical compound and disease context of PHF17

  • The lower the O2 saturation recorded at the entrance (2659 m) of Jade Mountain, the higher the score of the Lake Louise Acute Mountain Sickness Score (LLAMSS) [4].
 

Biological context of PHF17

 

Anatomical context of PHF17

  • Biochemical cell fractionation studies as well as confocal images of cells immunostained with a specific Jade-1 antibody revealed that endogenous Jade-1 is localized predominantly in the cell nucleus [2].
  • Fluoro Jade labeled reactive astrocytes and early differentiating astroglial cells [5].
 

Associations of PHF17 with chemical compounds

  • The sorption of artificial dye effluent made from two different dyes, Solar orange 7 GLL and Solar Jade Green FFB from Clariant, onto three different agricultural residues--barley husk, sugarcane bagasse, and wheat straw--was studied [8].
 

Physical interactions of PHF17

 

Regulatory relationships of PHF17

 

Analytical, diagnostic and therapeutic context of PHF17

References

  1. Jade-1, a candidate renal tumor suppressor that promotes apoptosis. Zhou, M.I., Foy, R.L., Chitalia, V.C., Zhao, J., Panchenko, M.V., Wang, H., Cohen, H.T. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
  2. von Hippel-Lindau partner Jade-1 is a transcriptional co-activator associated with histone acetyltransferase activity. Panchenko, M.V., Zhou, M.I., Cohen, H.T. J. Biol. Chem. (2004) [Pubmed]
  3. Fluoro-Jade: New fluorescent marker of Rosenthal fibers. Tanaka, K.F., Ochi, N., Hayashi, T., Ikeda, E., Ikenaka, K. Neurosci. Lett. (2006) [Pubmed]
  4. Acute mountain sickness in Jade Mountain climbers of Taiwan. Kao, W.F., Kuo, C.C., Hsu, T.F., Chang, H., Sung, Y.Y., Yen, D.H., Wu, J.K., Lee, C.H. Aviation, space, and environmental medicine. (2002) [Pubmed]
  5. Fluoro Jade stains early and reactive astroglia in the primate cerebral cortex. Colombo, J.A., Puissant, V.I. J. Histochem. Cytochem. (2002) [Pubmed]
  6. Tumor suppressor von Hippel-Lindau (VHL) stabilization of Jade-1 protein occurs through plant homeodomains and is VHL mutation dependent. Zhou, M.I., Wang, H., Foy, R.L., Ross, J.J., Cohen, H.T. Cancer Res. (2004) [Pubmed]
  7. Controlled cortical impact in swine: pathophysiology and biomechanics. Manley, G.T., Rosenthal, G., Lam, M., Morabito, D., Yan, D., Derugin, N., Bollen, A., Knudson, M.M., Panter, S.S. J. Neurotrauma (2006) [Pubmed]
  8. Remediation of textile effluent using agricultural residues. Chandran, C.B., Singh, D., Nigam, P. Appl. Biochem. Biotechnol. (2002) [Pubmed]
  9. The von Hippel-Lindau tumor suppressor stabilizes novel plant homeodomain protein Jade-1. Zhou, M.I., Wang, H., Ross, J.J., Kuzmin, I., Xu, C., Cohen, H.T. J. Biol. Chem. (2002) [Pubmed]
  10. Role of Jade-1 in the histone acetyltransferase (HAT) HBO1 complex. Foy, R.L., Song, I.Y., Chitalia, V.C., Cohen, H.T., Saksouk, N., Cayrou, C., Vaziri, C., Côté, J., Panchenko, M.V. J. Biol. Chem. (2008) [Pubmed]
 
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