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Chemical Compound Review

AC1NSE0G     4-[(2E)-2-(2-oxonaphthalen- 1...

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Disease relevance of Persian Orange


High impact information on Persian Orange

  • Photobleaching of Orange II within seconds using the oxone/Co2+ reagent through Fenton-like chemistry [6].
  • Azo1 was also able to metabolize Orange II, Amaranth, Ponceau BS and Ponceau S azo dyes [7].
  • The apparent discoloration kinetics of Orange II with the four catalysts at two different initial solution pH values was also investigated [8].
  • The reaction activation energy calculated was 9.94 kJ/mol, indicating that the photo-Fenton discoloration of Orange II is not very sensitive to reaction temperature [9].
  • The same dose of Orange II to rats showed a relatively less but significant effect in nuclear (62%), mitochondrial (59%) and microsomal (38%) membranes [2].

Chemical compound and disease context of Persian Orange

  • Orange II azoreductase [NAD(P)H: 1-(4'-sulfophenylazo)-2-naphthol oxidoreductase], an enzyme catalyzing the reductive cleavage of the azo bridge of Orange II and related dyes, was purified to electrophoretic homogeneity from Pseudomonas species, strain KF46 [3].
  • Parenteral administration of Metanil yellow and Orange II to rats at a dose of 80 mg/kg body weight for 3 days caused a significant induction of ethoxyresorufin-O-deethylase (40-190%), aniline hydroxylase (27-92%), aryl hydrocarbon hydroxylase (50-62%) and aminopyrine N-demethylase (42-49%) activities [10].

Biological context of Persian Orange

  • Fresnel lens to concentrate solar energy for the photocatalytic decoloration and mineralization of orange II in aqueous solution [11].
  • Oral LD50 value of orange II in both male and female rats was calculated to be more than 10.56 g/kg body weight [5].
  • The reductive biotransformation of acid orange 7 (AO7) was explored in a lab-scale upflow anaerobic sludge blanket (UASB) reactor at low hydraulic residence times (HRT) [12].
  • Orange II, C.I. Acid Orange 7 (AO7), is oxidatively decolorized via catalytic oxidation by iron(III) phthalocyanine-tetrasulfonic acid (Fe(III)-PcTS) as a biomimetic catalyst and KHSO(5) as an oxygen donor [13].
  • The water purification potential of this new class of compound was evaluated by studying the photodegradation of Acid Orange 7 (AO7) and E. coli [14].

Anatomical context of Persian Orange


Associations of Persian Orange with other chemical compounds


Gene context of Persian Orange

  • The photodestruction of Acid Orange 7 (AO7), an anionic acidic dye, was studied in the UV/H2O2 process [20].
  • Under optimal conditions (pH=3.0, 10 mM H(2)O(2), and 1 x 8W UVC), 100% discoloration and 50-60% TOC removal of 0.2 mM Orange II can be achieved in 90 and 120 min, respectively [21].
  • The sorption of artificial dye effluent made from two different dyes, Solar orange 7 GLL and Solar Jade Green FFB from Clariant, onto three different agricultural residues--barley husk, sugarcane bagasse, and wheat straw--was studied [22].
  • Orange II induced cytogenetical changes in albino mice [23].
  • The adsorption capacity was pH dependent with a maximum value of 109.0 mg/g at pH 7 for AR88, 133.5 mg/g at pH 3 for AG3 and 109.6 mg/g at pH 3 for AO7, respectively, was obtained [24].

Analytical, diagnostic and therapeutic context of Persian Orange

  • For the gelatin-free microspheres, a close correlation of SA release and AO release was observed (2% loading), suggesting a release mechanism that was controlled dominantly by degradation [25].
  • A packed-bed fungal bioreactor for the continuous decolourisation of azo-dyes (Orange II) [26].
  • Experiments above demonstrate that TiO(2) modified beta-PbO(2) electrode, which realized TiO(2) immobilization successfully, performed well in EAPD of Acid Orange 7 [27].
  • The adsorption capacities of the derived adsorbents for Acid Orange 10 were measured at 20 degrees C and 40 degrees C to gain further insights into the acidic surface oxides of the adsorbent from the results of Fourier transform infrared (FTIR) spectroscopy analysis and pH measurement [28].
  • The influence of a toxic organic compound (acid orange 7) on biofilm microprofiles was also monitored using microelectrodes [29].


  1. Influence of aromatic substitution patterns on azo dye degradability by Streptomyces spp. and Phanerochaete chrysosporium. Pasti-Grigsby, M.B., Paszczynski, A., Goszczynski, S., Crawford, D.L., Crawford, R.L. Appl. Environ. Microbiol. (1992) [Pubmed]
  2. Lipid peroxidation of ultrastructural components of rat liver induced by metanil yellow and orange II: comparison with blend. Ramachandani, S., Das, M., Khanna, S.K. Toxicology and industrial health. (1992) [Pubmed]
  3. Properties of purified Orange II azoreductase, the enzyme initiating azo dye degradation by Pseudomonas KF46. Zimmermann, T., Kulla, H.G., Leisinger, T. Eur. J. Biochem. (1982) [Pubmed]
  4. Cloning of DNA from a Rhodococcus strain conferring the ability to decolorize sulfonated azo dyes. Heiss, G.S., Gowan, B., Dabbs, E.R. FEMS Microbiol. Lett. (1992) [Pubmed]
  5. Acute and short-term toxicity studies on orange II. Singh, R.L., Khanna, S.K., Singh, G.B. Veterinary and human toxicology. (1987) [Pubmed]
  6. Photobleaching of Orange II within seconds using the oxone/Co2+ reagent through Fenton-like chemistry. Fernandez, J., Nadtochenko, V., Kiwi, J. Chem. Commun. (Camb.) (2003) [Pubmed]
  7. Biochemical and molecular characterization of an azoreductase from Staphylococcus aureus, a tetrameric NADPH-dependent flavoprotein. Chen, H., Hopper, S.L., Cerniglia, C.E. Microbiology (Reading, Engl.) (2005) [Pubmed]
  8. Discoloration and mineralization of Orange II using different heterogeneous catalysts containing Fe: a comparative study. Feng, J., Hu, X., Yue, P.L. Environ. Sci. Technol. (2004) [Pubmed]
  9. Novel bentonite clay-based Fe-nanocomposite as a heterogeneous catalyst for photo-Fenton discoloration and mineralization of Orange II. Feng, J., Hu, X., Yue, P.L. Environ. Sci. Technol. (2004) [Pubmed]
  10. Effect of metanil yellow, orange II and their blend on hepatic xenobiotic metabolizing enzymes in rats. Ramchandani, S., Das, M., Khanna, S.K. Food Chem. Toxicol. (1994) [Pubmed]
  11. Fresnel lens to concentrate solar energy for the photocatalytic decoloration and mineralization of orange II in aqueous solution. Monteagudo, J.M., Durán, A. Chemosphere (2006) [Pubmed]
  12. Enhanced decolourisation of acid orange 7 in a continuous UASB reactor with quinones as redox mediators. Cervantes, F.J., van der Zee, F.P., Lettinga, G., Field, J.A. Water Sci. Technol. (2001) [Pubmed]
  13. Decolorization of orange II by catalytic oxidation using iron (III) phthalocyanine-tetrasulfonic acid. Rismayani, S., Fukushima, M., Ichikawa, H., Tatsumi, K. Journal of hazardous materials. (2004) [Pubmed]
  14. Novel tiO2 nanocatalysts for wastewater purification: tapping energy from the sun. Liu, Y., Li, J., Qiu, X., Burda, C. Water Sci. Technol. (2006) [Pubmed]
  15. Kinetic response of testis to Orange II administration in rat. Singh, G.B., Khanna, S.K. Indian J. Exp. Biol. (1977) [Pubmed]
  16. Kinetic modeling on photooxidative degradation of C.I. Acid Orange 7 in a tubular continuous-flow photoreactor. Behnajady, M.A., Modirshahla, N. Chemosphere (2006) [Pubmed]
  17. Photocatalytic degradation of azo dyes by nitrogen-doped TiO2 nanocatalysts. Liu, Y., Chen, X., Li, J., Burda, C. Chemosphere (2005) [Pubmed]
  18. Accelerated photobleaching of orange II on novel (H5FeW12O4010H2O)/silica structured fabrics. Li, D., Yuranova, T., Albers, P., Kiwi, J. Water Res. (2004) [Pubmed]
  19. Kinetics of anaerobic biodecolourisation of azo dyes. Kalyuzhnyi, S., Yemashova, N., Fedorovich, V. Water Sci. Technol. (2006) [Pubmed]
  20. Photodestruction of Acid Orange 7 (AO7) in aqueous solutions by UV/H2O2: influence of operational parameters. Behnajady, M.A., Modirshahla, N., Shokri, M. Chemosphere (2004) [Pubmed]
  21. Discoloration and mineralization of Orange II by using a bentonite clay-based Fe nanocomposite film as a heterogeneous photo-Fenton catalyst. Feng, J., Hu, X., Yue, P.L. Water Res. (2005) [Pubmed]
  22. Remediation of textile effluent using agricultural residues. Chandran, C.B., Singh, D., Nigam, P. Appl. Biochem. Biotechnol. (2002) [Pubmed]
  23. Orange II induced cytogenetical changes in albino mice. Prasad, O., Rastogi, P.B. Experientia (1982) [Pubmed]
  24. Batch and column studies on biosorption of acid dyes on fresh water macro alga Azolla filiculoides. Padmesh, T.V., Vijayaraghavan, K., Sekaran, G., Velan, M. Journal of hazardous materials. (2005) [Pubmed]
  25. Polyanhydride microspheres that display near-constant release of water-soluble model drug compounds. Tabata, Y., Langer, R. Pharm. Res. (1993) [Pubmed]
  26. A packed-bed fungal bioreactor for the continuous decolourisation of azo-dyes (Orange II). Mielgo, I., Moreira, M.T., Feijoo, G., Lema, J.M. J. Biotechnol. (2001) [Pubmed]
  27. Electrochemically assisted photocatalytic degradation of Acid Orange 7 with beta-PbO2 electrodes modified by TiO2. Li, G., Qu, J., Zhang, X., Ge, J. Water Res. (2006) [Pubmed]
  28. Adsorption of acid dye onto activated carbons prepared from agricultural waste bagasse by ZnCl2 activation. Tsai, W.T., Chang, C.Y., Lin, M.C., Chien, S.F., Sun, H.F., Hsieh, M.F. Chemosphere (2001) [Pubmed]
  29. Monitoring the influence of toxic compounds on microbial denitrifying biofilm processes. Li, J., Bishop, P.L. Water Sci. Technol. (2003) [Pubmed]
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