Gene Review:
CASP10 - caspase 10, apoptosis-related cysteine...
Homo sapiens
Synonyms:
ALPS2, Apoptotic protease Mch-4, CASP-10, Caspase-10, FAS-associated death domain protein interleukin-1B-converting enzyme 2, ...
- Inactivating mutations of CASP10 gene in non-Hodgkin lymphomas. Shin, M.S., Kim, H.S., Kang, C.S., Park, W.S., Kim, S.Y., Lee, S.N., Lee, J.H., Park, J.Y., Jang, J.J., Kim, C.W., Kim, S.H., Lee, J.Y., Yoo, N.J., Lee, S.H. Blood (2002)
- Association of the CASP10 V410I variant with reduced familial breast cancer risk and interaction with the CASP8 D302H variant. Frank, B., Hemminki, K., Wappenschmidt, B., Meindl, A., Klaes, R., Schmutzler, R.K., Bugert, P., Untch, M., Bartram, C.R., Burwinkel, B. Carcinogenesis (2006)
- Variation in CASP10 gene is associated with idiopathic talipes equinovarus. Heck, A.L., Bray, M.S., Scott, A., Blanton, S.H., Hecht, J.T. Journal of pediatric orthopedics. (2005)
- In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains. Fernandes-Alnemri, T., Armstrong, R.C., Krebs, J., Srinivasula, S.M., Wang, L., Bullrich, F., Fritz, L.C., Trapani, J.A., Tomaselli, K.J., Litwack, G., Alnemri, E.S. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases. Srinivasula, S.M., Ahmad, M., Fernandes-Alnemri, T., Litwack, G., Alnemri, E.S. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Development and refinement of pregnane X receptor (PXR) DNA binding site model using information theory: insights into PXR-mediated gene regulation. Vyhlidal, C.A., Rogan, P.K., Leeder, J.S. J. Biol. Chem. (2004)
- Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling. Vincenz, C., Dixit, V.M. J. Biol. Chem. (1997)
- Genetic analysis identifies putative tumor suppressor sites at 2q35-q36.1 and 2q36.3-q37.1 involved in cervical cancer progression. Narayan, G., Pulido, H.A., Koul, S., Lu, X.Y., Harris, C.P., Yeh, Y.A., Vargas, H., Posso, H., Terry, M.B., Gissmann, L., Schneider, A., Mansukhani, M., Rao, P.H., Murty, V.V. Oncogene (2003)
- Regulation of GRB2 and FLICE2 expression by TNF-alpha in rheumatoid synovium. Huh, S.J., Paik, D.J., Chung, H.S., Youn, J. Immunol. Lett. (2003)
- Caspase-10 involvement in cytotoxic drug-induced apoptosis of tumor cells. Filomenko, R., Prévotat, L., Rébé, C., Cortier, M., Jeannin, J.F., Solary, E., Bettaieb, A. Oncogene (2006)
- Cloning and characterization of three novel genes, ALS2CR1, ALS2CR2, and ALS2CR3, in the juvenile amyotrophic lateral sclerosis (ALS2) critical region at chromosome 2q33-q34: candidate genes for ALS2. Hadano, S., Yanagisawa, Y., Skaug, J., Fichter, K., Nasir, J., Martindale, D., Koop, B.F., Scherer, S.W., Nicholson, D.W., Rouleau, G.A., Ikeda, J., Hayden, M.R. Genomics (2001)
- Molecular cloning and characterization of two novel pro-apoptotic isoforms of caspase-10. Ng, P.W., Porter, A.G., Jänicke, R.U. J. Biol. Chem. (1999)
- Characterization of gene expression in major types of salivary gland carcinomas with epithelial differentiation. Leivo, I., Jee, K.J., Heikinheimo, K., Laine, M., Ollila, J., Nagy, B., Knuutila, S. Cancer Genet. Cytogenet. (2005)