Gene Review:
LEU2 - 3-isopropylmalate dehydrogenase
Saccharomyces cerevisiae S288c
Synonyms:
3-IPM-DH, Beta-IPM dehydrogenase, IMDH, YCL018W, YCL18W
Chen,
- Vectors for the expression and analysis of DNA-binding proteins in yeast. Bonner, J.J. Gene (1991)
- Isolation of the gene encoding the yeast TATA binding protein TFIID: a gene identical to the SPT15 suppressor of Ty element insertions. Hahn, S., Buratowski, S., Sharp, P.A., Guarente, L. Cell (1989)
- Yeast TATA-binding protein TFIID binds to TATA elements with both consensus and nonconsensus DNA sequences. Hahn, S., Buratowski, S., Sharp, P.A., Guarente, L. Proc. Natl. Acad. Sci. U.S.A. (1989)
- In vivo functional characterization of a yeast nucleotide sequence: construction of a mini-Mu derivative adapted to yeast. Daignan-Fornier, B., Bolotin-Fukuhara, M. Gene (1988)
- Amplification of plasmid copy number by thymidine kinase expression in Saccharomyces cerevisiae. Zealey, G.R., Goodey, A.R., Piggott, J.R., Watson, M.E., Cafferkey, R.C., Doel, S.M., Carter, B.L., Wheals, A.E. Mol. Gen. Genet. (1988)
- Nucleotide sequence of yeast LEU2 shows 5'-noncoding region has sequences cognate to leucine. Andreadis, A., Hsu, Y.P., Kohlhaw, G.B., Schimmel, P. Cell (1982)
- Unequal meiotic recombination within tandem arrays of yeast ribosomal DNA genes. Petes, T.D. Cell (1980)
- Role of an upstream regulatory element in leucine repression of the Saccharomyces cerevisiae leu2 gene. Martinez-Arias, A., Yost, H.J., Casadaban, M.J. Nature (1984)
- Expression of a bacterial modification methylase gene in yeast. Fehér, Z., Kiss, A., Venetianer, P. Nature (1983)
- LEU2 directed expression of beta-galactosidase activity and phleomycin resistance in Yarrowia lipolytica. Gaillardin, C., Ribet, A.M. Curr. Genet. (1987)
- Induction of intrachromosomal recombination in yeast by inhibition of thymidylate biosynthesis. Kunz, B.A., Taylor, G.R., Haynes, R.H. Genetics (1986)
- Isolation of the centromere-linked CDC10 gene by complementation in yeast. Clarke, L., Carbon, J. Proc. Natl. Acad. Sci. U.S.A. (1980)
- Structure of yeast LEU4. The 5' flanking region contains features that predict two modes of control and two productive translation starts. Beltzer, J.P., Chang, L.F., Hinkkanen, A.E., Kohlhaw, G.B. J. Biol. Chem. (1986)
- Analysis of full-length cDNA clones carrying GAL1 of Saccharomyces cerevisiae: a model system for cDNA expression. Miyajima, A., Nakayama, N., Miyajima, I., Arai, N., Okayama, H., Arai, K. Nucleic Acids Res. (1984)
- An allele of RFA1 suppresses RAD52-dependent double-strand break repair in Saccharomyces cerevisiae. Smith, J., Rothstein, R. Genetics (1999)
- SPL1-1, a Saccharomyces cerevisiae mutation affecting tRNA splicing. Kolman, C., Söll, D. J. Bacteriol. (1993)
- Characterization of a yeast nuclear gene (MST1) coding for the mitochondrial threonyl-tRNA1 synthetase. Pape, L.K., Koerner, T.J., Tzagoloff, A. J. Biol. Chem. (1985)
- Functional mitochondria are essential for Saccharomyces cerevisiae cellular resistance to bleomycin. He, C.H., Masson, J.Y., Ramotar, D. Curr. Genet. (1996)
- Vacuolar accumulation and extracellular extrusion of electrophilic compounds by wild-type and glutathione-deficient mutants of the methylotrophic yeast Hansenula polymorpha. Ubiyvovk, V.M., Maszewski, J., Bartosz, G., Sibirny, A.A. Cell Biol. Int. (2003)
- LEU3 of Saccharomyces cerevisiae activates multiple genes for branched-chain amino acid biosynthesis by binding to a common decanucleotide core sequence. Friden, P., Schimmel, P. Mol. Cell. Biol. (1988)
- The Saccharomyces cerevisiae Leu3 protein activates expression of GDH1, a key gene in nitrogen assimilation. Hu, Y., Cooper, T.G., Kohlhaw, G.B. Mol. Cell. Biol. (1995)
- Construction of a GAL1-regulated yeast cDNA expression library and its application to the identification of genes whose overexpression causes lethality in yeast. Liu, H., Krizek, J., Bretscher, A. Genetics (1992)
- Identification of ATP-NADH kinase isozymes and their contribution to supply of NADP(H) in Saccharomyces cerevisiae. Shi, F., Kawai, S., Mori, S., Kono, E., Murata, K. FEBS J. (2005)
- Two vectors for the insertion of mammalian selectable genes into yeast artificial chromosome cloned DNA. Tucker, R.M., Burke, D.T. Gene (1997)
- LEU3 of Saccharomyces cerevisiae encodes a factor for control of RNA levels of a group of leucine-specific genes. Friden, P., Schimmel, P. Mol. Cell. Biol. (1987)
- Mutational analysis of the mitochondrial Rieske iron-sulfur protein of Saccharomyces cerevisiae. I. Construction of a RIP1 deletion strain and isolation of temperature-sensitive mutants. Beckmann, J.D., Ljungdahl, P.O., Trumpower, B.L. J. Biol. Chem. (1989)
- Homology of yeast mitochondrial leucyl-tRNA synthetase and isoleucyl- and methionyl-tRNA synthetases of Escherichia coli. Tzagoloff, A., Akai, A., Kurkulos, M., Repetto, B. J. Biol. Chem. (1988)
- Regulation of yeast LEU2. Total deletion of regulatory gene LEU3 unmasks GCN4-dependent basal level expression of LEU2. Brisco, P.R., Kohlhaw, G.B. J. Biol. Chem. (1990)
- The MRE4 gene encodes a novel protein kinase homologue required for meiotic recombination in Saccharomyces cerevisiae. Leem, S.H., Ogawa, H. Nucleic Acids Res. (1992)
- A Tn10-lacZ-kanR-URA3 gene fusion transposon for insertion mutagenesis and fusion analysis of yeast and bacterial genes. Huisman, O., Raymond, W., Froehlich, K.U., Errada, P., Kleckner, N., Botstein, D., Hoyt, M.A. Genetics (1987)
- Low- and high-copy-number shuttle vectors for replication in the budding yeast Kluyveromyces lactis. Chen, X.J. Gene (1996)
- Cloning and sequence analysis of the LEU2 homologue gene from Pichia anomala. De la Rosa, J.M., Pérez, J.A., Gutiérrez, F., González, J.M., Ruiz, T., Rodríguez, L. Yeast (2001)
- Gene targeting by linear duplex DNA frequently occurs by assimilation of a single strand that is subject to preferential mismatch correction. Leung, W., Malkova, A., Haber, J.E. Proc. Natl. Acad. Sci. U.S.A. (1997)
- A short region from the LEU2 gene of Saccharomyces cerevisiae functions as an ARS in the yeast Saccharomyces exiguus Yp74L-3. Hisatomi, T., Wada, Y., Fujisaki, C., Tsuboi, M. Curr. Microbiol. (1998)
- Use of interplasmid recombination to generate stable selectable markers for yeast transformation: application to studies of actin gene control. Hubberstey, A.V., Wildeman, A.G. Genome (1990)
- On spontaneous mutagenesis and cell cultivation conditions. Lyubimova, K.A., Chepurnoy, A.I. Mutat. Res. (1992)