Gene Review:
COX17 - copper metallochaperone COX17
Saccharomyces cerevisiae S288c
Synonyms:
Cytochrome c oxidase copper chaperone, L1343, YLL009C
- Mutagenesis reveals a specific role for Cox17p in copper transport to cytochrome oxidase. Punter, F.A., Glerum, D.M. J. Biol. Chem. (2003)
- Identification of COX17 as a therapeutic target for non-small cell lung cancer. Suzuki, C., Daigo, Y., Kikuchi, T., Katagiri, T., Nakamura, Y. Cancer Res. (2003)
- The Puf3 protein is a transcript-specific regulator of mRNA degradation in yeast. Olivas, W., Parker, R. EMBO J. (2000)
- Mammalian copper chaperone Cox17p has an essential role in activation of cytochrome C oxidase and embryonic development. Takahashi, Y., Kako, K., Kashiwabara, S., Takehara, A., Inada, Y., Arai, H., Nakada, K., Kodama, H., Hayashi, J., Baba, T., Munekata, E. Mol. Cell. Biol. (2002)
- SCO1 and SCO2 act as high copy suppressors of a mitochondrial copper recruitment defect in Saccharomyces cerevisiae. Glerum, D.M., Shtanko, A., Tzagoloff, A. J. Biol. Chem. (1996)
- COX23, a homologue of COX17, is required for cytochrome oxidase assembly. Barros, M.H., Johnson, A., Tzagoloff, A. J. Biol. Chem. (2004)
- AtCOX17, an Arabidopsis homolog of the yeast copper chaperone COX17. Balandin, T., Castresana, C. Plant Physiol. (2002)
- Recruitment of the Puf3 protein to its mRNA target for regulation of mRNA decay in yeast. Jackson, J.S., Houshmandi, S.S., Lopez Leban, F., Olivas, W.M. RNA (2004)
- Yeast cox17 solution structure and Copper(I) binding. Abajian, C., Yatsunyk, L.A., Ramirez, B.E., Rosenzweig, A.C. J. Biol. Chem. (2004)
- Mutational analysis of the mitochondrial copper metallochaperone Cox17. Heaton, D., Nittis, T., Srinivasan, C., Winge, D.R. J. Biol. Chem. (2000)
- Characterization of COX17, a yeast gene involved in copper metabolism and assembly of cytochrome oxidase. Glerum, D.M., Shtanko, A., Tzagoloff, A. J. Biol. Chem. (1996)
- Purification, characterization, and localization of yeast Cox17p, a mitochondrial copper shuttle. Beers, J., Glerum, D.M., Tzagoloff, A. J. Biol. Chem. (1997)
- The P174L Mutation in Human Sco1 Severely Compromises Cox17-dependent Metallation but Does Not Impair Copper Binding. Cobine, P.A., Pierrel, F., Leary, S.C., Sasarman, F., Horng, Y.C., Shoubridge, E.A., Winge, D.R. J. Biol. Chem. (2006)
- Yeast Puf3 mutants reveal the complexity of Puf-RNA binding and identify a loop required for regulation of mRNA decay. Houshmandi, S.S., Olivas, W.M. RNA (2005)
- Plant copper chaperones. Wintz, H., Vulpe, C. Biochem. Soc. Trans. (2002)
- Specific copper transfer from the Cox17 metallochaperone to both Sco1 and Cox11 in the assembly of yeast cytochrome C oxidase. Horng, Y.C., Cobine, P.A., Maxfield, A.B., Carr, H.S., Winge, D.R. J. Biol. Chem. (2004)