Gene Review:
MAD1 - Mad1p
Saccharomyces cerevisiae S288c
Synonyms:
Mitotic arrest deficient protein 1, Spindle assembly checkpoint component MAD1, YGL086W
- Mad proteins contain a dominant transcription repression domain. Ayer, D.E., Laherty, C.D., Lawrence, Q.A., Armstrong, A.P., Eisenman, R.N. Mol. Cell. Biol. (1996)
- Feedback control of mitosis in budding yeast. Li, R., Murray, A.W. Cell (1991)
- Association of spindle assembly checkpoint component XMAD2 with unattached kinetochores. Chen, R.H., Waters, J.C., Salmon, E.D., Murray, A.W. Science (1996)
- Mitotic chromosome condensation in the rDNA requires TRF4 and DNA topoisomerase I in Saccharomyces cerevisiae. Castaño, I.B., Brzoska, P.M., Sadoff, B.U., Chen, H., Christman, M.F. Genes Dev. (1996)
- Spindle checkpoint proteins and chromosome-microtubule attachment in budding yeast. Gillett, E.S., Espelin, C.W., Sorger, P.K. J. Cell Biol. (2004)
- BubR1 is essential for kinetochore localization of other spindle checkpoint proteins and its phosphorylation requires Mad1. Chen, R.H. J. Cell Biol. (2002)
- Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast. Hardwick, K.G., Murray, A.W. J. Cell Biol. (1995)
- Ran GTPase regulates Mad2 localization to the nuclear pore complex. Quimby, B.B., Arnaoutov, A., Dasso, M. Eukaryotic Cell (2005)
- Bipolar orientation of chromosomes in Saccharomyces cerevisiae is monitored by Mad1 and Mad2, but not by Mad3. Lee, M.S., Spencer, F.A. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Interactions between Mad1p and the nuclear transport machinery in the yeast Saccharomyces cerevisiae. Scott, R.J., Lusk, C.P., Dilworth, D.J., Aitchison, J.D., Wozniak, R.W. Mol. Biol. Cell (2005)
- The yeast nuclear pore complex functionally interacts with components of the spindle assembly checkpoint. Iouk, T., Kerscher, O., Scott, R.J., Basrai, M.A., Wozniak, R.W. J. Cell Biol. (2002)
- SIN3-dependent transcriptional repression by interaction with the Mad1 DNA-binding protein. Kasten, M.M., Ayer, D.E., Stillman, D.J. Mol. Cell. Biol. (1996)
- The spindle checkpoint of budding yeast depends on a tight complex between the Mad1 and Mad2 proteins. Chen, R.H., Brady, D.M., Smith, D., Murray, A.W., Hardwick, K.G. Mol. Biol. Cell (1999)
- Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function. Brady, D.M., Hardwick, K.G. Curr. Biol. (2000)
- Budding yeast Bub2 is localized at spindle pole bodies and activates the mitotic checkpoint via a different pathway from Mad2. Fraschini, R., Formenti, E., Lucchini, G., Piatti, S. J. Cell Biol. (1999)
- Bub1p kinase activates the Saccharomyces cerevisiae spindle assembly checkpoint. Farr, K.A., Hoyt, M.A. Mol. Cell. Biol. (1998)