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Gene Review

lacY  -  galactoside permease

Escherichia coli O157:H7 str. EDL933

 
 
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Disease relevance of lacY

 

High impact information on lacY

 

Chemical compound and disease context of lacY

 

Biological context of lacY

 

Associations of lacY with chemical compounds

  • This cell contained a defect in the lacY gene that resulted in the formation of a transport system with a poor affinity for lactose [11].

References

  1. Site-specific mutagenesis of histidine residues in the lac permease of Escherichia coli. Padan, E., Sarkar, H.K., Viitanen, P.V., Poonian, M.S., Kaback, H.R. Proc. Natl. Acad. Sci. U.S.A. (1985) [Pubmed]
  2. Measurement of the proton motive force in Rhizobium meliloti with the Escherichia coli lacY gene product. Gober, J.W., Kashket, E.R. J. Bacteriol. (1985) [Pubmed]
  3. Fermentation of raffinose by lactose-fermenting strains of Yersinia enterocolitica and by sucrose-fermenting strains of Escherichia coli. Cornelis, G., Luke, R.K., Richmond, M.H. J. Clin. Microbiol. (1978) [Pubmed]
  4. Chromosomal integration of phage lambda by means of a DNA insertion element. MacHattie, L.A., Shapiro, J.A. Proc. Natl. Acad. Sci. U.S.A. (1978) [Pubmed]
  5. The lactose carrier of Klebsiella pneumoniae M5a1; the physiology of transport and the nucleotide sequence of the lacY gene. McMorrow, I., Chin, D.T., Fiebig, K., Pierce, J.L., Wilson, D.M., Reeve, E.C., Wilson, T.H. Biochim. Biophys. Acta (1988) [Pubmed]
  6. In vitro and in vivo products of E. coli lactose permease gene are identical. Ehring, R., Beyreuther, K., Wright, J.K., Overath, P. Nature (1980) [Pubmed]
  7. Genetic rearrangements and gene amplification in Escherichia coli: DNA sequences at the junctures of amplified gene fusions. Whoriskey, S.K., Nghiem, V.H., Leong, P.M., Masson, J.M., Miller, J.H. Genes Dev. (1987) [Pubmed]
  8. Stimulation of recombination between homologous sequences on plasmid DNA and chromosomal DNA in Escherichia coli by N-acetoxy-2-acetylaminofluorene. Luisi-DeLuca, C., Porter, R.D., Taylor, W.D. Proc. Natl. Acad. Sci. U.S.A. (1984) [Pubmed]
  9. Identification of valine 177 as a mutation altering specificity for transport of sugars by the Escherichia coli lactose carrier. Enhanced specificity for sucrose and maltose. King, S.C., Wilson, T.H. J. Biol. Chem. (1990) [Pubmed]
  10. Coordinate expression of a small polypeptide with the lactose carrier of Escherichia coli. Lagarias, D.M., Villarejo, M. J. Biol. Chem. (1985) [Pubmed]
  11. lacY mutant of Escherichia coli with altered physiology of lactose induction. Flagg, J.L., Wilson, T.H. J. Bacteriol. (1976) [Pubmed]
  12. Interaction of pyridostigmine bromide and N,N-diethyl-m-toluamide alone and in combination with P-glycoprotein expressed in Escherichia coli leaky mutant. El-Masry, E.M., Abou-Donia, M.B. J. Toxicol. Environ. Health Part A (2006) [Pubmed]
  13. Isolation, genetic analysis, and characterization of Escherichia coli mutants with defects in the lacY gene. Hobson, A.C., Gho, D., Müller-Hill, B. J. Bacteriol. (1977) [Pubmed]
  14. Cloning of chromosomal genes of Lactococcus by heterologous complementation: partial characterisation of a putative lactose transport gene. Ross, R., O'Gara, F., Condon, S. FEMS Microbiol. Lett. (1989) [Pubmed]
  15. Variable coordination of cotranscribed genes in Escherichia coli following antisense repression. Dryselius, R., Nikravesh, A., Kulyt??, A., Goh, S., Good, L. BMC Microbiol. (2006) [Pubmed]
  16. Transposable lambda placMu bacteriophages for creating lacZ operon fusions and kanamycin resistance insertions in Escherichia coli. Bremer, E., Silhavy, T.J., Weinstock, G.M. J. Bacteriol. (1985) [Pubmed]
 
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