Gene Review:
lacY - galactoside permease
Escherichia coli UTI89
- In vitro and in vivo products of E. coli lactose permease gene are identical. Ehring, R., Beyreuther, K., Wright, J.K., Overath, P. Nature (1980)
- Structure and function of facilitative sugar transporters. Barrett, M.P., Walmsley, A.R., Gould, G.W. Curr. Opin. Cell Biol. (1999)
- Effects of the putative neutrophil-generated toxin, hypochlorous acid, on membrane permeability and transport systems of Escherichia coli. Albrich, J.M., Gilbaugh, J.H., Callahan, K.B., Hurst, J.K. J. Clin. Invest. (1986)
- Structural evidence for induced fit and a mechanism for sugar/H+ symport in LacY. Mirza, O., Guan, L., Verner, G., Iwata, S., Kaback, H.R. EMBO J. (2006)
- Elucidation of substrate binding interactions in a membrane transport protein by mass spectrometry. Weinglass, A.B., Whitelegge, J.P., Hu, Y., Verner, G.E., Faull, K.F., Kaback, H.R. EMBO J. (2003)
- A polytopic membrane protein displays a reversible topology dependent on membrane lipid composition. Bogdanov, M., Heacock, P.N., Dowhan, W. EMBO J. (2002)
- Phospholipid-assisted protein folding: phosphatidylethanolamine is required at a late step of the conformational maturation of the polytopic membrane protein lactose permease. Bogdanov, M., Dowhan, W. EMBO J. (1998)
- The size of the lactose permease derived from rotational diffusion measurements. Dornmair, K., Corin, A.F., Wright, J.K., Jähnig, F. EMBO J. (1985)
- Site-directed alkylation and the alternating access model for LacY. Kaback, H.R., Dunten, R., Frillingos, S., Venkatesan, P., Kwaw, I., Zhang, W., Ermolova, N. Proc. Natl. Acad. Sci. U.S.A. (2007)
- Deduction of consensus binding sequences on proteins that bind IIAGlc of the phosphoenolpyruvate:sugar phosphotransferase system by cysteine scanning mutagenesis of Escherichia coli lactose permease. Sondej, M., Sun, J., Seok, Y.J., Kaback, H.R., Peterkofsky, A. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Changing the lactose permease of Escherichia coli into a galactose-specific symporter. Guan, L., Sahin-Toth, M., Kaback, H.R. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Variable coordination of cotranscribed genes in Escherichia coli following antisense repression. Dryselius, R., Nikravesh, A., Kulyt??, A., Goh, S., Good, L. BMC Microbiol. (2006)
- Conformational flexibility at the substrate binding site in the lactose permease of Escherichia coli. Weinglass, A.B., Kaback, H.R. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Arg-302 facilitates deprotonation of Glu-325 in the transport mechanism of the lactose permease from Escherichiacoli. Sahin-Toth, M., Kaback, H.R. Proc. Natl. Acad. Sci. U.S.A. (2001)
- Topology of allosteric regulation of lactose permease. Seok, Y.J., Sun, J., Kaback, H.R., Peterkofsky, A. Proc. Natl. Acad. Sci. U.S.A. (1997)
- In vitro membrane assembly of a polytopic, transmembrane protein results in an enzymatically active conformation. Ahrem, B., Hoffschulte, H.K., Müller, M. J. Cell Biol. (1989)
- An approach to membrane protein structure without crystals. Sorgen, P.L., Hu, Y., Guan, L., Kaback, H.R., Girvin, M.E. Proc. Natl. Acad. Sci. U.S.A. (2002)
- A phospholipid acts as a chaperone in assembly of a membrane transport protein. Bogdanov, M., Sun, J., Kaback, H.R., Dowhan, W. J. Biol. Chem. (1996)
- Orientation of substrate and two conformations of lactose permease. Dornmair, K., Jähnig, F. Biochemistry (1988)
- The N-terminal region of Escherichia coli lactose permease mediates membrane contact of the nascent polypeptide chain. Stochaj, U., Ehring, R. Eur. J. Biochem. (1987)
- The substrate-binding site in the lactose permease of Escherichia coli. Venkatesan, P., Kaback, H.R. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Distance determination in proteins using designed metal ion binding sites and site-directed spin labeling: application to the lactose permease of Escherichia coli. Voss, J., Hubbell, W.L., Kaback, H.R. Proc. Natl. Acad. Sci. U.S.A. (1995)
- Regulation of lactose permease activity by the phosphoenolpyruvate:sugar phosphotransferase system: evidence for direct binding of the glucose-specific enzyme III to the lactose permease. Osumi, T., Saier, M.H. Proc. Natl. Acad. Sci. U.S.A. (1982)
- Sugar transport by the bacterial phosphotransferase system. In vivo regulation of lactose transport in Escherichia coli by IIIGlc, a protein of the phosphoenolpyruvate:glycose phosphotransferase system. Mitchell, W.J., Saffen, D.W., Roseman, S. J. Biol. Chem. (1987)
- The structure of the lactose permease derived from Raman spectroscopy and prediction methods. Vogel, H., Wright, J.K., Jähnig, F. EMBO J. (1985)
- Manipulating phospholipids for crystallization of a membrane transport protein. Guan, L., Smirnova, I.N., Verner, G., Nagamori, S., Kaback, H.R. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Energetics of Ligand-induced Conformational Flexibility in the Lactose Permease of Escherichia coli. Nie, Y., Smirnova, I., Kasho, V., Kaback, H.R. J. Biol. Chem. (2006)
- Sequence alignment and homology threading reveals prokaryotic and eukaryotic proteins similar to lactose permease. Kasho, V.N., Smirnova, I.N., Kaback, H.R. J. Mol. Biol. (2006)