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Gene Review

galU  -  UTP-glucose-1-phosphate uridylyltransferase

Escherichia coli O157:H7 str. EDL933

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Disease relevance of galU


High impact information on galU


Chemical compound and disease context of galU


Analytical, diagnostic and therapeutic context of galU

  • The lactococcal galU gene was identified by a PCR approach using degenerate primers and was found by Northern blot analysis to be transcribed in a monocistronic RNA [9].


  1. Characterization of the galU gene of Streptococcus pneumoniae encoding a uridine diphosphoglucose pyrophosphorylase: a gene essential for capsular polysaccharide biosynthesis. Mollerach, M., López, R., García, E. J. Exp. Med. (1998) [Pubmed]
  2. Biological functions of UDP-glucose synthesis in Streptococcus mutans. Yamashita, Y., Tsukioka, Y., Nakano, Y., Tomihisa, K., Oho, T., Koga, T. Microbiology (Reading, Engl.) (1998) [Pubmed]
  3. Impact of heterologous expression of Escherichia coli UDP-glucose pyrophosphorylase on trehalose and glycogen synthesis in Corynebacterium glutamicum. Padilla, L., Morbach, S., Krämer, R., Agosin, E. Appl. Environ. Microbiol. (2004) [Pubmed]
  4. Biochemical and genetic characterization of osmoregulatory trehalose synthesis in Escherichia coli. Giaever, H.M., Styrvold, O.B., Kaasen, I., Strøm, A.R. J. Bacteriol. (1988) [Pubmed]
  5. Genetic analysis of Escherichia coli oligopeptide transport mutants. Andrews, J.C., Short, S.A. J. Bacteriol. (1985) [Pubmed]
  6. A locus involved in kanamycin, chloramphenicol and L-serine resistance is located in the bglY-galU region of the Escherichia coli K12 chromosome. Lejeune, P., Bertin, P., Walon, C., Willemot, K., Colson, C., Danchin, A. Mol. Gen. Genet. (1989) [Pubmed]
  7. cur-1, a mutation affecting a phenotype of sup+ strains of Escherichia coli. Diderichsen, B. Mol. Gen. Genet. (1980) [Pubmed]
  8. Biochemical characterization of the pneumococcal glucose 1-phosphate uridylyltransferase (GalU) essential for capsule biosynthesis. Bonofiglio, L., García, E., Mollerach, M. Curr. Microbiol. (2005) [Pubmed]
  9. Functional analysis of the Lactococcus lactis galU and galE genes and their impact on sugar nucleotide and exopolysaccharide biosynthesis. Boels, I.C., Ramos, A., Kleerebezem, M., de Vos, W.M. Appl. Environ. Microbiol. (2001) [Pubmed]
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