Disease relevance of Hemorrhoids

• Major hemorrhage occurred in patients with increased anatomic risk of bleeding (diverticulosis, hemorrhoids, cystitis), and was not a function of patient age, sex, anticoagulation control, or medications administered concurrently with warfarin [1].
• In women, severe overweight was associated with hypertension, diabetes, varicose veins, asthma/bronchitis, and hemorrhoids [2].
• CONCLUSION: Topically applied nitroglycerin ointment appears to have a therapeutic role in the treatment of thrombosed external hemorrhoids and anal fissure [3].
• In April 2001, the University of Pennsylvania (inventor again Alan D Schreiber) claimed the use of medroxyprogesterone acetate for treating IBD, CD, UC, food allergies, hemorrhoids and psoriasis in WO-00122959, entitled 'Method of treating inflammatory conditions with progesterone or progesterone analogs' [4].
• The purse-string anoscope of the PPH 01 kit (Ethicon Endo-Surgery, Cincinnati, USA) was modified to overcome the obstruction of the staple line by internal hemorrhoids and rectal mucosal prolapse [5].

High impact information on Hemorrhoids

• A comparison was made between the patterns of the ferrous sulfate absorption in the polycythemic patients and in five patients with low iron serum due to bleeding hemorrhoids [6].
• METHODS: Seventy consecutive patients (mean age, 56 years; 37 males) with Grade 3 or 4 hemorrhoids underwent the procedure for prolapsing hemorrhoids after perianal infiltration of 0.5 percent lidocaine with 1:200,000 epinephrine and supplemental conscious sedation [7].
• Conservative treatment of acute thrombosed external hemorrhoids with topical nifedipine [8].
• METHODS: Twenty-nine well-documented adult patients with first- or second-degree internal hemorrhoids were treated with calcium dobesilate for two weeks, while16 patients received only a high-fiber diet to serve as control [9].
• Local injection of bupivacaine after rubber band ligation of hemorrhoids: prospective, randomized study [10].

Chemical compound and disease context of Hemorrhoids

• The diosmin and placebo groups, with 50 patients each, were comparable in age, sex, symptoms, and the severity of the underlying hemorrhoids [11].
• Long-term results of large-dose, single-session phenol injection sclerotherapy for hemorrhoids [12].
• In the treatment group rubber band ligation was performed at three columns of hemorrhoids, and 1 to 2 ml of 2 percent lignocaine was injected into the banded hemorrhoidal tissue [13].
• METHODS: Ninety consecutive patients (50 males, 40 females), 80 percent of whom had second or third degree hemorrhoids, had ambulatory hemorrhoidectomy performed with a CO2 laser in the left lateral Sims position under local anesthesia and intravenous sedation [14].
• Treatment of acute strangulated internal hemorrhoids by topical application of isosorbide dinitrate ointment [15].

Gene context of Hemorrhoids

• For patients with internal hemorrhoids, the rate of positivity for fecal Lf was significantly higher than that for FOB [16].
• CONCLUSION: Large-dose, single-session sclerotherapy provides only short-term benefits in the majority of patients with symptomatic hemorrhoids [12].

Analytical, diagnostic and therapeutic context of Hemorrhoids

• One hundred thirty-five patients with a diagnosis of hemorrhoids were randomized to receive either photocoagulation (P) (N = 73) or injection sclerotherapy with phenol (I) (N = 62) [17].

References