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MeSH Review

Motor Neuron Disease

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Biological context of Motor Neuron Disease


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Gene context of Motor Neuron Disease


Analytical, diagnostic and therapeutic context of Motor Neuron Disease


  1. Unstable mutants in the peripheral endosomal membrane component ALS2 cause early-onset motor neuron disease. Yamanaka, K., Vande Velde, C., Eymard-Pierre, E., Bertini, E., Boespflug-Tanguy, O., Cleveland, D.W. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
  2. Spastin mutations in sporadic adult-onset upper motor neuron syndromes. Brugman, F., Wokke, J.H., Scheffer, H., Versteeg, M.H., Sistermans, E.A., van den Berg, L.H. Ann. Neurol. (2005) [Pubmed]
  3. Homozygous exon 7 deletion of the SMN centromeric gene (SMN2): a potential susceptibility factor for adult-onset lower motor neuron disease. Echaniz-Laguna, A., Guiraud-Chaumeil, C., Tranchant, C., Reeber, A., Melki, J., Warter, J.M. J. Neurol. (2002) [Pubmed]
  4. Treatable lower motor neuron disease due to vitamin D deficiency and secondary hyperparathyroidism. Whitaker, C.H., Malchoff, C.D., Felice, K.J. Amyotroph. Lateral Scler. Other Motor Neuron Disord. (2000) [Pubmed]
  5. Primary lateral sclerosis, hereditary spastic paraplegia, and mutations in the alsin gene: historical background for the first International Conference. Rowland, L.P. Amyotroph. Lateral Scler. Other Motor Neuron Disord. (2005) [Pubmed]
  6. Amyotrophic lateral sclerosis with dementia: the clinicopathological spectrum. Yoshida, M. Neuropathology : official journal of the Japanese Society of Neuropathology. (2004) [Pubmed]
  7. Clinical and neuropathologic variation in neuronal intermediate filament inclusion disease. Cairns, N.J., Grossman, M., Arnold, S.E., Burn, D.J., Jaros, E., Perry, R.H., Duyckaerts, C., Stankoff, B., Pillon, B., Skullerud, K., Cruz-Sanchez, F.F., Bigio, E.H., Mackenzie, I.R., Gearing, M., Juncos, J.L., Glass, J.D., Yokoo, H., Nakazato, Y., Mosaheb, S., Thorpe, J.R., Uryu, K., Lee, V.M., Trojanowski, J.Q. Neurology (2004) [Pubmed]
  8. Intraneuronal deposition of calcium and aluminium in amyotropic lateral sclerosis of Guam. Garruto, R.M., Swyt, C., Fiori, C.E., Yanagihara, R., Gajdusek, D.C. Lancet (1985) [Pubmed]
  9. Infantile-onset ascending hereditary spastic paralysis is associated with mutations in the alsin gene. Eymard-Pierre, E., Lesca, G., Dollet, S., Santorelli, F.M., di Capua, M., Bertini, E., Boespflug-Tanguy, O. Am. J. Hum. Genet. (2002) [Pubmed]
  10. DJ-1 mutations and parkinsonism-dementia-amyotrophic lateral sclerosis complex. Annesi, G., Savettieri, G., Pugliese, P., D'Amelio, M., Tarantino, P., Ragonese, P., La Bella, V., Piccoli, T., Civitelli, D., Annesi, F., Fierro, B., Piccoli, F., Arabia, G., Caracciolo, M., Cirò Candiano, I.C., Quattrone, A. Ann. Neurol. (2005) [Pubmed]
  11. Association between centromeric deletions of the SMN gene and sporadic adult-onset lower motor neuron disease. Moulard, B., Salachas, F., Chassande, B., Briolotti, V., Meininger, V., Malafosse, A., Camu, W. Ann. Neurol. (1998) [Pubmed]
  12. Experimental conduction block induced by serum from a patient with anti-GM1 antibodies. Santoro, M., Uncini, A., Corbo, M., Staugaitis, S.M., Thomas, F.P., Hays, A.P., Latov, N. Ann. Neurol. (1992) [Pubmed]
  13. A novel neuroprotective mechanism of riluzole: direct inhibition of protein kinase C. Noh, K.M., Hwang, J.Y., Shin, H.C., Koh, J.Y. Neurobiol. Dis. (2000) [Pubmed]
  14. Motor neuron diseases: comparison of single-voxel proton MR spectroscopy of the motor cortex with MR imaging of the brain. Chan, S., Shungu, D.C., Douglas-Akinwande, A., Lange, D.J., Rowland, L.P. Radiology. (1999) [Pubmed]
  15. Deficient RNA editing of GluR2 and neuronal death in amyotropic lateral sclerosis. Kwak, S., Kawahara, Y. J. Mol. Med. (2005) [Pubmed]
  16. Monoclonal IgMs with anti-Gal(beta 1-3) GalNAc activity in lower motor neuron disease; identification of glycoprotein antigens in neural tissue and cross-reactivity with serum immunoglobulins. Thomas, F.P., Lee, A.M., Romas, S.N., Latov, N. J. Neuroimmunol. (1989) [Pubmed]
  17. Intrathecal baclofen for spasticity in primary lateral sclerosis. Milano, J.B., Neto, M.C., Hunhevicz, S.C., Arruda, W.O., Ramina, R., Barros, E. J. Neurol. (2005) [Pubmed]
  18. Evoked potentials in motor system diseases. Cascino, G.D., Ring, S.R., King, P.J., Brown, R.H., Chiappa, K.H. Neurology (1988) [Pubmed]
  19. Patients with amyotrophic lateral sclerosis and other neurodegenerative diseases have increased levels of neurofilament protein in CSF. Rosengren, L.E., Karlsson, J.E., Karlsson, J.O., Persson, L.I., Wikkelsø, C. J. Neurochem. (1996) [Pubmed]
  20. The value of sphincter electromyography in urodynamics. Mayo, M.E. J. Urol. (1979) [Pubmed]
  21. 17q-linked frontotemporal dementia-amyotrophic lateral sclerosis without tau mutations with tau and alpha-synuclein inclusions. Wilhelmsen, K.C., Forman, M.S., Rosen, H.J., Alving, L.I., Goldman, J., Feiger, J., Lee, J.V., Segall, S.K., Kramer, J.H., Lomen-Hoerth, C., Rankin, K.P., Johnson, J., Feiler, H.S., Weiner, M.W., Lee, V.M., Trojanowski, J.Q., Miller, B.L. Arch. Neurol. (2004) [Pubmed]
  22. Immunocytochemical studies on synaptophysin in the anterior horn of lower motor neuron disease. Ikemoto, A., Kawanami, T., Llena, J.F., Hirano, A. J. Neuropathol. Exp. Neurol. (1994) [Pubmed]
  23. Amyloid neuropathy simulating lower motor neuron disease. Quattrini, A., Nemni, R., Sferrazza, B., Ricevuti, G., Dell'Antonio, G., Lazzerini, A., Iannaccone, S. Neurology (1998) [Pubmed]
  24. Gangliosides GM1 and GD1b are antigens for IgM M-protein in a patient with motor neuron disease. Freddo, L., Yu, R.K., Latov, N., Donofrio, P.D., Hays, A.P., Greenberg, H.S., Albers, J.W., Allessi, A.G., Keren, D. Neurology (1986) [Pubmed]
  25. Influence of muscle wasting on oral glucose tolerance testing. Moxley, R.T., Griggs, R.C., Forbes, G.B., Goldblatt, D., Donohoe, K. Clin. Sci. (1983) [Pubmed]
  26. A double-blind placebo-controlled study of 3,4-diaminopyridine in amytrophic lateral sclerosis patients on a rehabilitation unit. Aisen, M.L., Sevilla, D., Edelstein, L., Blass, J. J. Neurol. Sci. (1996) [Pubmed]
  27. A biotinidase Km variant causing late onset bilateral optic neuropathy. Ramaekers, V.T., Suormala, T.M., Brab, M., Duran, R., Heimann, G., Baumgartner, E.R. Arch. Dis. Child. (1992) [Pubmed]
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