Disease relevance of Mediastinal Cyst

• METHODS: We examined 31 patients with thymic tumors, including 14 patients with thymic cancer, 9 with invasive thymoma, 5 with noninvasive thymoma and 3 with thymic cysts [1].
• Histologically, all the tumors basically showed similar histopathologic features, namely, those described in multilocular thymic cysts, ie, cystic structures lined by either squamous or low cuboidal epithelium, lymphoid hyperplasia, cholesterol cleft granulomas, and remnants of thymic tissue [2].
• High-grade thymic carcinoma other than basaloid or mucoepidermoid type could be associated with multilocular thymic cyst: report of two cases [3].
• A thymic cyst may contain cholesterol crystals in the luminal fluid, cholesterol clefts, granulomas and lymphocytic follicles as well as Hassall corpuscles in the wall [4].
• There have been multiple case reports of rare complications of pericardial cysts including right ventricular outflow obstruction, pulmonary stenosis, pericardial tamponade, and partial erosion into the superior vena cava [5].

High impact information on Mediastinal Cyst

• High prevalence of estrogen and progesterone receptor expression in mediastinal cysts situated in the posterior mediastinum [6].
• A thymic cyst in one woman was weakly positive only for the ER [6].
• BACKGROUND: To identify and estimate the prevalence of mediastinal cysts lined by the epithelium expressing steroid receptors [6].
• Methicillin-resistant Staphylococcus aureus-infected pericardial cyst [7].
• This latter feature is demonstrated by incubation of fetal thymic lobes with deoxyguanosine (d-Guo), inducing a 2D-organized thymic stroma, with thymic cysts appearing [8].

Chemical compound and disease context of Mediastinal Cyst

• We report the case of a 41-year-old man with a pericardial cyst treated by percutaneous aspiration and ethanol injection [9].
• It is postulated that massive haemorrhages in thymic cysts produce large amounts of bilirubin, causing sludging of bile excretions in the liver [10].
• Gallium-67 uptake in a benign thymic cyst [11].
• Effects of hydrocortisone on the ultrastructure of the thymic cysts of chicks [12].

Anatomical context of Mediastinal Cyst

• In ciliated cells of thymic cysts in Nude mice, ciliary rootlets are constantly and closely related to smooth endoplasmic reticulum and clear vesicles [13].

Gene context of Mediastinal Cyst

• Management of a mediastinal cyst causing hyperparathyroidism and tracheal obstruction [14].
• CONCLUSIONS: Simple mediastinoscopic removal of mediastinal cysts offers the same potential for diagnosis and treatment as more conventional methods, with a potential for less morbid and more cost-effective care [15].
• Elevated levels of carcinoembryonic antigen and cancer antigen 125 in a thymic cyst [16].
• Pericardial cyst in the midline position [17].
• Pericardial cyst with partial erosion of the superior vena cava. An unusual case [18].

References