The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Mediastinum


High impact information on Mediastinum


Chemical compound and disease context of Mediastinum


Biological context of Mediastinum


Anatomical context of Mediastinum


Associations of Mediastinum with chemical compounds


Gene context of Mediastinum

  • Detection of DNA abnormalities by arbitrarily primed PCR fingerprinting: amplification of the MDM2 gene in a mediastinum fibrosarcoma [26].
  • The ALK-positive examples occur in children and young adults, involving a variety of sites, such as the abdomen, mesentery, liver, bladder, mediastinum, lung and bone [27].
  • Twenty-seven patients had high positive rhTSH Tg testing and (131)I uptake was detected in lung, bone, or mediastinum in 11 [28].
  • Thymoma is the most common tumor of the anterior-superior mediastinum [29].
  • In contrast, none of 61 cases of other malignant neoplasms with a tendency to involve the mediastinum was immunoreactive for CD5, including 40 nonthymic carcinomas and 13 malignant germ cell neoplasma [30].

Analytical, diagnostic and therapeutic context of Mediastinum


  1. Immunomorphologic classification of spontaneous lymphoid cell neoplasms occurring in female BALB/c mice. Pattengale, P.K., Frith, C.H. J. Natl. Cancer Inst. (1983) [Pubmed]
  2. Primary diffuse large B-cell lymphoma of the mediastinum: outcome following high-dose chemotherapy and autologous hematopoietic cell transplantation. Sehn, L.H., Antin, J.H., Shulman, L.N., Mauch, P., Elias, A., Kadin, M.E., Wheeler, C. Blood (1998) [Pubmed]
  3. High frequency of benign mediastinal uptake of gallium-67 after completion of chemotherapy in children with high-grade non-Hodgkin's lymphoma. Peylan-Ramu, N., Haddy, T.B., Jones, E., Horvath, K., Adde, M.A., Magrath, I.T. J. Clin. Oncol. (1989) [Pubmed]
  4. 18fluorodeoxyglucose positron emission tomography to detect mediastinal or internal mammary metastases in breast cancer. Eubank, W.B., Mankoff, D.A., Takasugi, J., Vesselle, H., Eary, J.F., Shanley, T.J., Gralow, J.R., Charlop, A., Ellis, G.K., Lindsley, K.L., Austin-Seymour, M.M., Funkhouser, C.P., Livingston, R.B. J. Clin. Oncol. (2001) [Pubmed]
  5. Vinblastine, bleomycin, and methotrexate chemotherapy plus extended-field radiotherapy in early, favorably presenting, clinically staged Hodgkin's patients: the Gruppo Italiano per lo Studio dei Linfomi Experience. Gobbi, P.G., Pieresca, C., Frassoldati, A., Carotenuto, M., Di Renzo, N., La Sala, A., Berté, R., Avanzini, P., Federico, M., Silingardi, V., Ascari, E. J. Clin. Oncol. (1996) [Pubmed]
  6. Barium or gastrografin: which contrast media for diagnosis of esophageal tears? James, A.E., Montali, R.J., Chaffee, V., Strecker, E.P., Vessal, K. Gastroenterology (1975) [Pubmed]
  7. Successful therapy of convoluted T-lymphoblastic lymphoma in the adult. Levine, A.M., Forman, S.J., Meyer, P.R., Koehler, S.C., Liebman, H., Paganini-Hill, A., Pockros, A., Lukes, R.J., Feinstein, D.I. Blood (1983) [Pubmed]
  8. Accuracy of helical computed tomography and [18F] fluorodeoxyglucose positron emission tomography for identifying lymph node mediastinal metastases in potentially resectable non-small-cell lung cancer. Pozo-Rodríguez, F., Martín de Nicolás, J.L., Sánchez-Nistal, M.A., Maldonado, A., García de Barajas, S., Calero-García, R., Pozo, M.A., Martín-Escribano, P., Martín-García, I., García-Lujan, R., Lopez-Encuentra, A., Arenas de Pablo, A. J. Clin. Oncol. (2005) [Pubmed]
  9. [18F]fluorodeoxyglucose positron emission tomography in the diagnosis of cancer in patients with paraneoplastic neurological syndrome and anti-Hu antibodies. Antoine, J.C., Cinotti, L., Tilikete, C., Bouhour, F., Camdessanché, J.P., Confavreux, C., Vighetto, A., Renault-Mannel, V., Michel, D., Honnorat, J. Ann. Neurol. (2000) [Pubmed]
  10. Thymoma: state of the art. Thomas, C.R., Wright, C.D., Loehrer, P.J. J. Clin. Oncol. (1999) [Pubmed]
  11. Within-patient variability of (18)F-FDG: standardized uptake values in normal tissues. Paquet, N., Albert, A., Foidart, J., Hustinx, R. J. Nucl. Med. (2004) [Pubmed]
  12. Hypertrophied bronchial artery at thin-section CT in patients with bronchiectasis: correlation with CT angiographic findings. Song, J.W., Im, J.G., Shim, Y.S., Park, J.H., Yeon, K.M., Han, M.C. Radiology. (1998) [Pubmed]
  13. Unexpected uptake of technetium 99m hexakis-2-methoxy-isobutylisonitrile in giant lymph node hyperplasia of the mediastinum (Castleman's disease). Aktolun, C., Bayhan, H., Celasun, B., Kir, M.K. European journal of nuclear medicine. (1991) [Pubmed]
  14. Steroid therapy as treatment for idiopathic fibrosis of the retroperitoneum and mediastinum. Feild, C., Arnold, W., Gloster, E.S., Sharp, G., Redman, J. Pediatrics (1986) [Pubmed]
  15. Induction therapy for esophageal cancer with paclitaxel and hyperfractionated radiotherapy: a phase I and II study. Wright, C.D., Wain, J.C., Lynch, T.J., Choi, N.C., Grossbard, M.L., Carey, R.W., Moncure, A.C., Grillo, H.C., Mathisen, D.J. J. Thorac. Cardiovasc. Surg. (1997) [Pubmed]
  16. A morphologic and statistical comparative study of small-cell carcinoma and non-Hodgkin's lymphoma in fine-needle aspiration biopsy material from lymph nodes. De Las Casas, L.E., Gokden, M., Mukunyadzi, P., White, P., Baker, S.J., Hermonat, P.L., You, H., Korourian, S., Malak, S.F., Miranda, R.N. Diagn. Cytopathol. (2004) [Pubmed]
  17. Acute respiratory distress syndrome: CT findings during partial liquid ventilation. Meaney, J.F., Kazerooni, E.A., Garver, K.A., Hirschl, R.B. Radiology. (1997) [Pubmed]
  18. Thymic uptake of iodine-131 in the anterior mediastinum. Veronikis, I.E., Simkin, P., Braverman, L.E. J. Nucl. Med. (1996) [Pubmed]
  19. Enhanced CD4 reconstitution by grafting neonatal porcine tissue in alternative locations is associated with donor-specific tolerance and suppression of preexisting xenoreactive T cells. Rodriguez-Barbosa, J.I., Zhao, Y., Barth, R., Zhao, G., Arn, J.S., Sachs, D.H., Sykes, M. Transplantation (2001) [Pubmed]
  20. Gallium-67 in the evaluation of sarcoidosis: correlations with serum angiotensin-converting enzyme and bronchoalveolar lavage. Beaumont, D., Herry, J.Y., Sapene, M., Bourguet, P., Larzul, J.J., de Labarthe, B. Thorax (1982) [Pubmed]
  21. Extragonadal germ cell tumor of mediastinum with high serum level of carcinoembryonic antigen and carbohydrate antigen 19-9. Kitsukawa, S.I., Kin, T., Tsukamoto, T., Yonese, J., Ishikawa, Y., Fukui, I. J. Urol. (2000) [Pubmed]
  22. Gallium scans in patients with mediastinal Hodgkin's disease treated with chemotherapy. Cooper, D.L., Caride, V.J., Zloty, M., Germino, J., Farber, L.R., Hoffer, P.B. J. Clin. Oncol. (1993) [Pubmed]
  23. Pulmonary mycobacterial infections in AIDS: characteristic pattern of thallium and gallium scan mismatch. Lee, V.W., Cooley, T.P., Fuller, J.D., Ward, R.J., Farber, H.W. Radiology. (1994) [Pubmed]
  24. Combined fluorine-18-FDG and carbon-11-methionine PET for diagnosis of tumors in lung and mediastinum. Nettelbladt, O.S., Sundin, A.E., Valind, S.O., Gustafsson, G.R., Lamberg, K., Långström, B., Björnsson, E.H. J. Nucl. Med. (1998) [Pubmed]
  25. Effects of losartan and its combination with quinapril on the cardiac sympathetic nervous system and neurohormonal status in essential hypertension. Sakata, K., Yoshida, H., Obayashi, K., Ishikawa, J., Tamekiyo, H., Nawada, R., Doi, O. J. Hypertens. (2002) [Pubmed]
  26. Detection of DNA abnormalities by arbitrarily primed PCR fingerprinting: amplification of the MDM2 gene in a mediastinum fibrosarcoma. Kuchiki, H., Yasuda, J., Kayama, T., Murakami, Y., Sekiya, T. Biochem. Biophys. Res. Commun. (1999) [Pubmed]
  27. Timely topic: anaplastic lymphoma kinase (ALK) spreads its influence. Cheuk, W., Chan, J.K. Pathology. (2001) [Pubmed]
  28. Clinical value of different responses of serum thyroglobulin to recombinant human thyrotropin in the follow-up of patients with differentiated thyroid carcinoma. David, A., Blotta, A., Rossi, R., Zatelli, M.C., Bondanelli, M., Roti, E., Braverman, L.E., Busutti, L., degli Uberti, E.C. Thyroid (2005) [Pubmed]
  29. Heritable lympho-epithelial thymoma resulting from a transgene insertional mutation. Nakajima, H., Nakajima, H.O., Soonpaa, M.H., Jing, S., Field, L.J. Oncogene (2000) [Pubmed]
  30. Thymic carcinomas, but not thymomas and carcinomas of other sites, show CD5 immunoreactivity. Dorfman, D.M., Shahsafaei, A., Chan, J.K. Am. J. Surg. Pathol. (1997) [Pubmed]
  31. Radiologic evaluation of the mediastinum in myasthenia gravis. Janssen, R.S., Kaye, A.D., Lisak, R.P., Schatz, N.J., Arger, P.A., Savino, P.J. Neurology (1983) [Pubmed]
  32. Gallium scanning by conventional imaging and emission computed tomography in the pretreatment evaluation of lung cancer. Broughton, D.L., Gibson, C.J., Crake, T., Pearce, S.J., Leonard, R.C. Thorax (1985) [Pubmed]
  33. Induction chemotherapy plus high-dose radiotherapy versus radiotherapy alone in locally advanced unresectable non-small-cell lung cancer. Crinò, L., Latini, P., Meacci, M., Corgna, E., Maranzano, E., Darwish, S., Minotti, V., Santucci, A., Tonato, M. Ann. Oncol. (1993) [Pubmed]
  34. Somatostatin receptor scintigraphy in forty-eight patients with the Zollinger-Ellison syndrome. GRESZE: Groupe d'Etude du Syndrome de Zollinger-Ellison. de Kerviler, E., Cadiot, G., Lebtahi, R., Faraggi, M., Le Guludec, D., Mignon, M. European journal of nuclear medicine. (1994) [Pubmed]
  35. Technetium-99m methoxyisobutylisonitrile localizes an ectopic ACTH-producing tumour: case report and review of the literature. Jacobsson, H., Wallin, G., Werner, S., Larsson, S.A. European journal of nuclear medicine. (1994) [Pubmed]
WikiGenes - Universities