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Disease relevance of Trichuriasis


High impact information on Trichuriasis

  • INTERPRETATION: Symptomless trichuriasis impairs growth and albendazole or pyrantel may affect growth, independently of a therapeutic action on parasites [6].
  • Although hemoglobin values tended to be slightly lower in Trichuris-infected children, there was no association between trichuriasis and serum iron or transferrin saturation values [7].
  • CONCLUSIONS: There is an acute phase response in intense trichuriasis and a specific elevation of plasma fibronectin [8].
  • We measured plasma concentrations of cortisol and aldosterone before and after administration of adrenocorticotropin (ACTH) in dogs with trichuriasis [9].
  • In vivo neutralization experiments using anti-cytokine monoclonal antibodies show that critical cytokines are involved, with interferon-gamma playing an important role in the establishment of chronic trichuriasis and interleukin-4 in expulsion of the parasite from the gut [10].

Chemical compound and disease context of Trichuriasis


Anatomical context of Trichuriasis


  1. A comparative trial of oxantel-pyrantel and mebendazole in multiple helminth infection in school children. Dissanaike, A.S. Drugs (1978) [Pubmed]
  2. Cortisone-induced immunotolerance to nematode infection in CBA/Ca mice. II. A model for human chronic trichuriasis. Lee, T.D., Wakelin, D. Immunology (1983) [Pubmed]
  3. A comparison of the efficacy of single doses of albendazole, ivermectin, and diethylcarbamazine alone or in combinations against Ascaris and Trichuris spp. Belizario, V.Y., Amarillo, M.E., de Leon, W.U., de los Reyes, A.E., Bugayong, M.G., Macatangay, B.J. Bull. World Health Organ. (2003) [Pubmed]
  4. Ovicidal effects of albendazole in human ascariasis, ancylostomiasis and trichuriasis. Maisonneuve, H., Rossignol, J.F., Addo, A., Mojon, M. Ann. Trop. Med. Parasitol. (1985) [Pubmed]
  5. Comparative clinical studies of nitazoxanide, albendazole and praziquantel in the treatment of ascariasis, trichuriasis and hymenolepiasis in children from Peru. Juan, J.O., Lopez Chegne, N., Gargala, G., Favennec, L. Trans. R. Soc. Trop. Med. Hyg. (2002) [Pubmed]
  6. Randomised trial of albendazole and pyrantel in symptomless trichuriasis in children. Forrester, J.E., Bailar, J.C., Esrey, S.A., José, M.V., Castillejos, B.T., Ocampo, G. Lancet (1998) [Pubmed]
  7. Is trichuriasis associated with iron deficiency anemia? Greenberg, E.R., Cline, B.L. Am. J. Trop. Med. Hyg. (1979) [Pubmed]
  8. Plasma proteins in children with trichuris dysentery syndrome. Cooper, E.S., Ramdath, D.D., Whyte-Alleng, C., Howell, S., Serjeant, B.E. J. Clin. Pathol. (1997) [Pubmed]
  9. Basal and ACTH-stimulated plasma aldosterone concentrations are normal or increased in dogs with trichuriasis-associated pseudohypoadrenocorticism. Graves, T.K., Schall, W.D., Refsal, K., Nachreiner, R.F. J. Vet. Intern. Med. (1994) [Pubmed]
  10. Cytokine-mediated regulation of intestinal helminth infections: the Trichuris muris model. Grencis, R.K. Ann. Trop. Med. Parasitol. (1993) [Pubmed]
  11. Benzimidazoles in the treatment of trichuriasis: a review. Rossignol, J.F., Maisonneuve, H. Ann. Trop. Med. Parasitol. (1984) [Pubmed]
  12. Treatment of Trichuris trichiura infection with a single dose of oxantel pamoate. Peldán, K., Pitkänen, T. Scand. J. Infect. Dis. (1982) [Pubmed]
  13. Experiencw with bitoscanate in hookworm disease and trichuriasis in Mexico. Biagi, F. Progress in drug research. Fortschritte der Arzneimittelforschung. Progrès des recherches pharmaceutiques. (1975) [Pubmed]
  14. Soil-transmitted helminthic infection and its effect on nutritional status of adolescent schoolgirls of low socioeconomic status in Sri Lanka. Atukorala, T.M., Lanerolle, P. J. Trop. Pediatr. (1999) [Pubmed]
  15. Angioedema due to diphetarsone and a review of its toxicity. McIntyre, L., Krajden, S., Keystone, J.S. Tropical and geographical medicine. (1983) [Pubmed]
  16. The intestinal gland of Trichinella spiralis with emphasis on morphology and antigenicity. Takahashi, Y., Uno, T., Mizuno, N., Aisaka, A., Yagi, J., Araki, T. Journal of electron microscopy. (1990) [Pubmed]
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