Disease relevance of Calicivirus, Feline

• Feline lung monolayer cultures were treated with either a feline interferon (IFN) or one of two recombinant human alpha-IFNs and then challenged with feline herpesvirus 1 (FHV-1), feline calicivirus (F-9 strain), or vesicular stomatitis virus [1].
• Chlorine dioxide (ClO2) inactivation experiments were conducted with adenovirus type 40 (AD40) and feline calicivirus (FCV) [2].
• Equine herpesvirus-4 and feline herpesvirus-1 did not remain infectious in proparacaine at any time > or = 1 h post inoculation, but feline calicivirus was recovered at up to 24 h post inoculation [3].
• Analysis of the N-terminal polypeptide of the capsid precursor protein and the ORF3 product of feline calicivirus [4].

High impact information on Calicivirus, Feline

• The ultrastructural morphogenesis of pulmonary lesions was studied in cats exposed to either aerosols of feline calicivirus (FCV) or high concentrations of NO2 [5].
• Junctional adhesion molecule 1 is a functional receptor for feline calicivirus [6].
• Mutagenesis of tyrosine 24 in the VPg protein is lethal for feline calicivirus [7].
• Processing map and essential cleavage sites of the nonstructural polyprotein encoded by ORF1 of the feline calicivirus genome [8].
• Expression of the region of the feline calicivirus (FCV) ORF1 encoded by nucleotides 3233 to 4054 in an in vitro rabbit reticulocyte system resulted in synthesis of an active proteinase that specifically processes the viral nonstructural polyprotein [9].

Chemical compound and disease context of Calicivirus, Feline

• To prove that viral infectivity was lost upon contact with the SDS/EDTA-treated strips, feline calicivirus F9 (10(7) TCID(50)/ml) was loaded onto the strips [10].
• Effect of orally administered ribavirin on experimental feline calicivirus infection in cats [11].
• Testing against feline calicivirus produced a log10 reduction factor of 2.38 by the test formulation; in contrast, the log10 reduction factors with 70% ethanol and 70% propan-1-ol were 0.68 and 0.70, respectively [12].
• Feline calicivirus, a nonenveloped virus, was present in fluorescein for 7 days [3].
• Immunohistochemical detection of feline calicivirus in formalin-fixed, paraffin-embedded specimens [13].

Anatomical context of Calicivirus, Feline

• An immunohistochemical technique was developed for detection of feline calicivirus (FCV) in formalin-fixed, paraffin-embedded cultured cells and tissues [13].

Gene context of Calicivirus, Feline

• Feline calicivirus (FCV) nonstructural proteins are translated as part of a large polyprotein that undergoes autocatalytic processing by the virus-encoded 3C-like proteinase [8].
• Cleavage of eukaryotic initiation factor eIF4G and inhibition of host-cell protein synthesis during feline calicivirus infection [14].
• Vesicular stomatitis virus was more sensitive to each IFN than were FHV-1 or feline calicivirus F-9 [1].
• However, the precursor was processed to a 57 kDa protein and a 22 kDa polypeptide by the proteinase of feline calicivirus (FCV) when this was co-expressed with ORF2 [15].

References