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MeSH Review

Circovirus

 
 
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Disease relevance of Circovirus

 

High impact information on Circovirus

  • The ORF3 Protein of Porcine Circovirus Type 2 Is Involved in Viral Pathogenesis In Vivo [5].
  • Porcine circovirus 2 uses heparan sulfate and chondroitin sulfate B glycosaminoglycans as receptors for its attachment to host cells [6].
  • Epitope mapping of the major capsid protein of type 2 porcine circovirus (PCV2) by using chimeric PCV1 and PCV2 [7].
  • CNPV genes lacking homologues in FWPV encode proteins similar to ubiquitin, interleukin-10-like proteins, tumor necrosis factor receptor, PIR1 RNA phosphatase, thioredoxin binding protein, MyD116 domain proteins, circovirus Rep proteins, and the nucleotide metabolism proteins thymidylate kinase and ribonucleotide reductase small subunit [8].
  • A chimeric porcine circovirus (PCV) with the immunogenic capsid gene of the pathogenic PCV type 2 (PCV2) cloned into the genomic backbone of the nonpathogenic PCV1 induces protective immunity against PCV2 infection in pigs [9].
 

Chemical compound and disease context of Circovirus

 

Biological context of Circovirus

 

Anatomical context of Circovirus

 

Gene context of Circovirus

 

Analytical, diagnostic and therapeutic context of Circovirus

References

  1. Comparison of the structures of three circoviruses: chicken anemia virus, porcine circovirus type 2, and beak and feather disease virus. Crowther, R.A., Berriman, J.A., Curran, W.L., Allan, G.M., Todd, D. J. Virol. (2003) [Pubmed]
  2. A comparison of in situ hybridization and immunohistochemistry for the detection of a new porcine circovirus in formalin-fixed tissues from pigs with post-weaning multisystemic wasting syndrome (PMWS). McNeilly, F., Kennedy, S., Moffett, D., Meehan, B.M., Foster, J.C., Clarke, E.G., Ellis, J.A., Haines, D.M., Adair, B.M., Allan, G.M. J. Virol. Methods (1999) [Pubmed]
  3. Distribution of porcine parvovirus in porcine circovirus 2-infected pigs with postweaning multisystemic wasting syndrome as shown by in-situ hybridization. Choi, C., Chae, C. J. Comp. Pathol. (2000) [Pubmed]
  4. In vitro expression, monoclonal antibody and bioactivity for capsid protein of porcine circovirus type II without nuclear localization signal. Zhou, J.Y., Shang, S.B., Gong, H., Chen, Q.X., Wu, J.X., Shen, H.G., Chen, T.F., Guo, J.Q. J. Biotechnol. (2005) [Pubmed]
  5. The ORF3 Protein of Porcine Circovirus Type 2 Is Involved in Viral Pathogenesis In Vivo. Liu, J., Chen, I., Du, Q., Chua, H., Kwang, J. J. Virol. (2006) [Pubmed]
  6. Porcine circovirus 2 uses heparan sulfate and chondroitin sulfate B glycosaminoglycans as receptors for its attachment to host cells. Misinzo, G., Delputte, P.L., Meerts, P., Lefebvre, D.J., Nauwynck, H.J. J. Virol. (2006) [Pubmed]
  7. Epitope mapping of the major capsid protein of type 2 porcine circovirus (PCV2) by using chimeric PCV1 and PCV2. Lekcharoensuk, P., Morozov, I., Paul, P.S., Thangthumniyom, N., Wajjawalku, W., Meng, X.J. J. Virol. (2004) [Pubmed]
  8. The genome of canarypox virus. Tulman, E.R., Afonso, C.L., Lu, Z., Zsak, L., Kutish, G.F., Rock, D.L. J. Virol. (2004) [Pubmed]
  9. A chimeric porcine circovirus (PCV) with the immunogenic capsid gene of the pathogenic PCV type 2 (PCV2) cloned into the genomic backbone of the nonpathogenic PCV1 induces protective immunity against PCV2 infection in pigs. Fenaux, M., Opriessnig, T., Halbur, P.G., Elvinger, F., Meng, X.J. J. Virol. (2004) [Pubmed]
  10. Development of a polyclonal-antibody-based immunohistochemical method for the detection of type 2 porcine circovirus in formalin-fixed, paraffin-embedded tissue. Sorden, S.D., Harms, P.A., Nawagitgul, P., Cavanaugh, D., Paul, P.S. J. Vet. Diagn. Invest. (1999) [Pubmed]
  11. Effects of dexamethasone on the pathogenesis of porcine circovirus type 2 infection in piglets. Kawashima, K., Tsunemitsu, H., Horino, R., Katsuda, K., Onodera, T., Shoji, T., Kubo, M., Haritani, M., Murakami, Y. J. Comp. Pathol. (2003) [Pubmed]
  12. Differentiation of porcine circovirus 1 and 2 in formalin-fixed, paraffin-wax-embedded tissues from pigs with postweaning multisystemic wasting syndrome by in-situ hybridisation. Kim, J., Chae, C. Res. Vet. Sci. (2001) [Pubmed]
  13. Open reading frame 2 of porcine circovirus type 2 encodes a major capsid protein. Nawagitgul, P., Morozov, I., Bolin, S.R., Harms, P.A., Sorden, S.D., Paul, P.S. J. Gen. Virol. (2000) [Pubmed]
  14. Apoptosis in lymphoid organs of pigs naturally infected by porcine circovirus type 2. Resendes, A.R., Majó, N., Segalés, J., Mateu, E., Calsamiglia, M., Domingo, M. J. Gen. Virol. (2004) [Pubmed]
  15. Enhancement of porcine circovirus 2 replication in porcine cell lines by IFN-gamma before and after treatment and by IFN-alpha after treatment. Meerts, P., Misinzo, G., Nauwynck, H.J. J. Interferon Cytokine Res. (2005) [Pubmed]
  16. Replication of porcine circovirus type 1 requires two proteins encoded by the viral rep gene. Mankertz, A., Hillenbrand, B. Virology (2001) [Pubmed]
  17. Differential recognition of ORF2 protein from type 1 and type 2 porcine circoviruses and identification of immunorelevant epitopes. Mahé, D., Blanchard, P., Truong, C., Arnauld, C., Le Cann, P., Cariolet, R., Madec, F., Albina, E., Jestin, A. J. Gen. Virol. (2000) [Pubmed]
  18. Sequence of porcine circovirus DNA: affinities with plant circoviruses. Meehan, B.M., Creelan, J.L., McNulty, M.S., Todd, D. J. Gen. Virol. (1997) [Pubmed]
  19. Detection and in vitro and in vivo characterization of porcine circovirus DNA from a porcine-derived commercial pepsin product. Fenaux, M., Opriessnig, T., Halbur, P.G., Xu, Y., Potts, B., Meng, X.J. J. Gen. Virol. (2004) [Pubmed]
  20. Optimized protocols for the detection of porcine circovirus 2 DNA from formalin-fixed paraffin-embedded tissues using nested polymerase chain reaction and comparison of nested PCR with in situ hybridization. Kim, J., Chae, C. J. Virol. Methods (2001) [Pubmed]
  21. Development of an ELISA based on the baculovirus-expressed capsid protein of porcine circovirus type 2 as antigen. Liu, C., Ihara, T., Nunoya, T., Ueda, S. J. Vet. Med. Sci. (2004) [Pubmed]
 
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