High impact information on Octodon

• Cloning of complementary DNAs encoding islet amyloid polypeptide, insulin, and glucagon precursors from a New World rodent, the degu, Octodon degus [1].
• Human-like rodent amyloid-beta-peptide determines Alzheimer pathology in aged wild-type Octodon degu [2].
• The influence of early parental deprivation on the development of tyrosine hydroxylase- and 5-hydroxytryptamine-immunoreactive fiber innervation of subregions of the orbital prefrontal cortex (ventrolateral orbital, lateral orbital and agranular insular cortex) was quantitatively investigated in the precocious lagomorph Octodon degus [3].
• This study utilized a diurnal rodent, Octodon degus, to test the prediction that the alteration of cortisol levels would affect the reentrainment rate of circadian locomotor rhythms [4].
• These data clarify that the sex difference in sensitivity to non-photic odor effects on circadian reentrainment is caused by both the testosterone's inhibitory effects (Octodon degus. J. Biol. Rhythms 18 (2003) 43-50) and the enhancing effects of progesterone and estrogen [5].

Biological context of Octodon

• Identification of androgen binding-protein (ABP) from testis and epididymis of the seasonal rodent, Octodon degus (Molina, 1872) [6].
• Estrus- and steroid-induced changes in circadian rhythms in a diurnal rodent, Octodon degus [7].

Anatomical context of Octodon

• The main protein of enriched and purified amyloid from Octodon degus pancreatic islets was identified as insulin [8].

Associations of Octodon with chemical compounds

• The data obtained from these analyses indicate that both human and Octodon degu lenses contain a heptitol and an octitol, sugars which have not previously been reported to be present in any animal tissue [9].
• Subcutaneous injections of [des-Asp1]-angiotensin I [( des-Asp1]-AI), angiotensin II (AII), and angiotensin III (AIII) induced drinking in the laboratory rat and the South American rodent Octodon degus, but not in the gerbil [10].
• We investigated seasonal patterns of plasma glucocorticosteroids (GCs) in both sexes and testosterone (T) in males in relation to the annual cycle in central Chile of a natural population of the degu (Octodon degus), a caviomorph rodent [11].
• Drug metabolism in Octodon degus: low inductive effect of phenobarbital [12].
• We studied the effects of chronic exposure to malathion in the kidney of Octodon degus, a caviomorph whose habitat may be exposed to pesticides currently used in Chilean agriculture [13].

Gene context of Octodon

• ABP, a Sertoli cell secretory product, was identified in the seasonal rodent Octodon degus (Molina, 1872) [6].
• The Octodon degus has been reported to have higher aldose reductase activity in the lens compared to the gerbil and rat [14].
• PATIENTS: Case 1, a 3-year-old girl, had a kerion due to TM transmitted by an octodon, and a facial skin eruption suggestive of systemic lupus erythematosus [15].

References