Disease relevance of Temporal Arteritis

• Patients with low-ESR temporal arteritis were similar to the other groups, except that they had a higher mean hemoglobin level than the high-ESR group and a significant increase in the percentage of patients (4 of 5) who had a previous diagnosis of polymyalgia rheumatica or had received steroid therapy compared with either of the other groups [1].
• Multinodular goitre with giant cell vasculitis of thyroid arteries in a woman with temporal arteritis [2].
• An elderly woman receiving long term treatment with prednisone and azathioprine for cryptogenic chronic active hepatitis developed granulomatous lipophagic panniculitis and temporal arteritis [3].
• Corticosteroid-induced osteoporosis is a common occurrence among several different patient populations, including individuals undergoing therapy for rheumatoid arthritis, temporal arteritis, polymyalgia rheumatica, chronic lung disease, asthma and organ transplantation [4].
• Acute renal failure induced by nimesulide in a patient suffering from temporal arteritis [5].

High impact information on Temporal Arteritis

• Reversal of blindness in temporal arteritis with methylprednisolone [6].
• Wegener's granulomatosis requires therapy with cyclophosphamide; temporal arteritis, with corticosteroids [7].
• Temporal arteritis specimens had clearly enhanced immunostaining for MMP-9 compared with normal arteries [8].
• The latter finding suggests that even low-dose steroid therapy can lower the ESR in patients with temporal arteritis [1].
• Patients with severe, disabling PMR had DR4 more frequently (90%) than did those with moderate symptoms who required medical care because of cranial arteritis manifestations (41.6%) (P less than 0.05) [9].

Chemical compound and disease context of Temporal Arteritis

• Long-term treatment of temporal arteritis with dapsone [10].
• Temporal arteritis revealed by a syndrome of inappropriate secretion of antidiuretic hormone [11].
• Transient resolution of headache in giant cell temporal arteritis after sumatriptan [12].
• The eruption flared whenever the patient received low doses of prednisone to control symptoms of temporal arteritis [13].
• Tongue necrosis secondary to ergotamine tartrate in a patient with temporal arteritis [14].

Biological context of Temporal Arteritis

• HLA-DR4 alleles were not associated with any clinical phenotypes of PMR/GCA, whereas MBL variant alleles were associated with cranial arteritis, high erythrocyte sedimentation rate, and low B-hemoglobin [15].

Anatomical context of Temporal Arteritis

• There was no correlation between the decrease in T8 (a cytotoxic suppressor T cell subset) and steroid therapy, disease activity, and temporal arteritis, nor between this decrease and the T gamma percentage and the presence of circulating immune complexes (CIC) [16].
• Macrophages contain 92-kd gelatinase (MMP-9) at the site of degenerated internal elastic lamina in temporal arteritis [8].
• The inflammation of the rheumatoid arthritis (RA), polymyalgia rheumatica, and temporal arteritis can be assessed by the erythrocyte sedimentation rate (ESR) [17].
• Although results of a temporal artery biopsy were negative, he was treated with prednisone for presumed temporal arteritis [18].

Gene context of Temporal Arteritis

• Temporal arteritis with normal ESR [19].
• Coma is rare in temporal arteritis (TA) [20].
• PURPOSE: To evaluate magnetic resonance (MR) imaging findings of radiation-induced cranial arteritis regarding arterial wall thickening and degree of enhancement, as well as to compare the findings with those of idiopathic moyamoya disease [21].
• METHODS: A 10-year retrospective review of all cases seen at the Geisinger Medical Center showed 271 cases of temporal arteritis and four cases with concomitant sensorineural hearing loss [22].
• Von Willebrand factor in the outcome of temporal arteritis [23].

Analytical, diagnostic and therapeutic context of Temporal Arteritis

• In biopsies from normal-looking skin, immune complexes in the dermo-epidermal junction zone were found by a direct immunofluorescence technique in 14 of 17 patients with systemic lupus erythematosus, in 6 of 12 patients with rheumatoid arthritis, but in none of 10 patients with temporal arteritis and 25 normal controls [24].

References