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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Mucocele

  • Sinus mucocele is rare in the paediatric age, and so far no prevalence data have been reported in children with Cystic Fibrosis (CF) [1].

High impact information on Mucocele

  • On the basis of these results, the authors conclude that the use of gadopentetate dimeglumine for contrast enhancement at MR imaging is useful for differentiating mucoceles from neoplasms in the sinonasal tract [2].
  • Six cases demonstrated co-existing neoplasm and mucocele: Gadolinium-enhanced MR enabled correct differentiation of five of these lesions, while unenhanced MR enabled correct differentiation of three [2].
  • Intracranial mucoceles with midline fusion defects [3].
  • Mucoceles of the appendix are a rare group of lesions thought to occur as a sequelae of luminal obstruction as well as certain benign and malignant neoplasms of the appendix [4].
  • In accordance with the proposed traumatic origin of extravasation mucocele, histological changes were classified on the basis of mucin extravasation and cyst formation [5].

Chemical compound and disease context of Mucocele


Anatomical context of Mucocele


Gene context of Mucocele

  • SUBJECTS AND METHODS: Five MSG tissue sections from SS and seven from mucocele patients were stained immunohistochemically using antibody to IGF-1 receptor and insulin receptor in a horse radish peroxidase and DAB system [16].
  • Significant correlation between matrix metalloproteinase activity and tumor necrosis factor-alpha in salivary extravasation mucoceles [13].
  • Carcinoembryonic antigen elevation due to bowel sequestration with mucocele formation following colonic resection [17].
  • We report a case of bowel sequestration with mucocele formation at the site of previous colo-colic anastomosis causing a mild elevation in CEA [17].
  • We examined the content of type IV collagenases and plasminogen activators (PAs) in luminal fluid of four extravasation mucoceles by means of gelatin or casein zymography [18].


  1. Paranasal mucoceles in children with cystic fibrosis. Di Cicco, M., Costantini, D., Padoan, R., Colombo, C. Int. J. Pediatr. Otorhinolaryngol. (2005) [Pubmed]
  2. Use of gadolinium-enhanced MR imaging for differentiating mucoceles from neoplasms in the paranasal sinuses. Lanzieri, C.F., Shah, M., Krauss, D., Lavertu, P. Radiology. (1991) [Pubmed]
  3. Intracranial mucoceles with midline fusion defects. Ching, H.S., Lindsay, K.W., O'Reilly, B.F. J. Neurol. Neurosurg. Psychiatr. (1996) [Pubmed]
  4. Mucocele of the appendix: computed tomographic, endoscopic, and pathologic correlation. Isaacs, K.L., Warshauer, D.M. Am. J. Gastroenterol. (1992) [Pubmed]
  5. Myxoglobulosis in oral extravasation mucocele: an entity? Shah, K.A. Histopathology (2003) [Pubmed]
  6. Voluminous frontoethmoidal mucocele with epidural involvement. Surgical treatment by coronal approach. Molteni, G., Spinelli, R., Panigatti, S., Colombo, L., Ronchi, P. Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale. (2003) [Pubmed]
  7. Mucosal preservation in the treatment of mucocele with CO2 laser. Kopp, W.K., St-Hilaire, H. J. Oral Maxillofac. Surg. (2004) [Pubmed]
  8. A case of thallium-201 accumulation by mucocele. Huguet, M., Lomeña, F., Catafau, A., Pavia, J., Setoain, F.J., Setoain, J. Clinical nuclear medicine. (1996) [Pubmed]
  9. Multiple oral mucoceles treated with gamma-linolenic acid: report of a case. McCaul, J.A., Lamey, P.J. The British journal of oral & maxillofacial surgery. (1994) [Pubmed]
  10. Local steroid therapy for oral mucoceles. Tashiro, H., Tomoyose, Y., Shinohara, M., Saza, H. Fukuoka Igaku Zasshi (1983) [Pubmed]
  11. Bilateral congenital lacrimal sac mucoceles with nasal extension and drainage. Divine, R.D., Anderson, R.L., Bumsted, R.M. Arch. Ophthalmol. (1983) [Pubmed]
  12. Natural history of the obstructed rabbit appendix: observations with radiography, sonography, and CT. Dachman, A.H., Nichols, J.B., Patrick, D.H., Lichtenstein, J.E. AJR. American journal of roentgenology. (1987) [Pubmed]
  13. Significant correlation between matrix metalloproteinase activity and tumor necrosis factor-alpha in salivary extravasation mucoceles. Hoque, M.O., Azuma, M., Sato, M. J. Oral Pathol. Med. (1998) [Pubmed]
  14. Efficacy of endoscopic sinus surgery for paranasal sinus mucocele including modified endoscopic Lothrop procedure for frontal sinus mucocele. Khong, J.J., Malhotra, R., Selva, D., Wormald, P.J. The Journal of laryngology and otology. (2004) [Pubmed]
  15. Expression of transforming growth factor-alpha in adenoid cystic carcinoma of the salivary gland. Chiang, C.P., Chen, C.H., Liu, B.Y., Sun, A., Leu, J.S., Wang, J.T. J. Formos. Med. Assoc. (2001) [Pubmed]
  16. IGF-1 and insulin receptor expression in the minor salivary gland tissues of Sjögren's syndrome and mucoceles--immunohistochemical study. Katz, J., Stavropoulos, F., Cohen, D., Robledo, J., Stewart, C., Heft, M. Oral diseases. (2003) [Pubmed]
  17. Carcinoembryonic antigen elevation due to bowel sequestration with mucocele formation following colonic resection. Haber, M.M., Leon, M.E., Bakker, J.E., Nagle, D. Arch. Pathol. Lab. Med. (2003) [Pubmed]
  18. Proteolytic enzymes in salivary extravasation mucoceles. Azuma, M., Tamatani, T., Fukui, K., Yuki, T., Hoque, M.O., Yoshida, H., Sato, M. J. Oral Pathol. Med. (1995) [Pubmed]
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