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MeSH Review


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Disease relevance of Turbinates


High impact information on Turbinates


Chemical compound and disease context of Turbinates


Biological context of Turbinates


Anatomical context of Turbinates


Associations of Turbinates with chemical compounds

  • Characterization and autoradiographic localization of histamine H1 receptors in human nasal turbinates [24].
  • METHODS: To determine a role for MMS-68 in the regulation of nasal mucus, we labeled human nasal turbinates with tritiated glucosamine and assayed for the ability of the previously purified MMS-68 (stock solution) to induce mucus-like glycoconjugate release (MLGC) [25].
  • In situ hybridization with digoxigenin-labeled RNA probes was performed on surgical specimens of human nasal turbinates [26].
  • A biopsy specimen of the nasal inferior turbinate was obtained before and 24 hours after local nasal provocation with grass pollen extract after 6 weeks of treatment with either topical fluticasone propionate (n = 9) or placebo (n = 8) nasal spray twice daily [27].
  • Each nostril of the patients will be randomly assigned in a double blind manner to receive either GR213487B liquid nasal spray or the lipid alone (ie. control administered as liposome), by topical application directed at the inferior turbinate [28].

Gene context of Turbinates

  • The ciliated cells of the nasal turbinates demonstrated strong iNOS positivity, but no significant cNOS immunoreactivity [29].
  • No ER or PR were found in any of the tumor components, nor have they been detected in control nasal turbinates [30].
  • The only difference seen between normal and VMR turbinates was a slight decrease in MUC1 expression in the VMR group [31].
  • TFF1 and TFF3 mRNA were detected in the human turbinate tissues examined [32].
  • Immunohistochemical expression of VEGF and VEGF receptors in nasal polyps as compared to normal turbinate mucosa [33].

Analytical, diagnostic and therapeutic context of Turbinates


  1. Persistence of abnormal chloride ion permeability in cystic fibrosis nasal epithelial cells in heterologous culture. Yankaskas, J.R., Knowles, M.R., Gatzy, J.T., Boucher, R.C. Lancet (1985) [Pubmed]
  2. Glucocorticosteroids inhibit mRNA expression for eotaxin, eotaxin-2, and monocyte-chemotactic protein-4 in human airway inflammation with eosinophilia. Jahnsen, F.L., Haye, R., Gran, E., Brandtzaeg, P., Johansen, F.E. J. Immunol. (1999) [Pubmed]
  3. Nasal polyposis: immunohistochemistry and bioelectrical findings (a hypothesis for the development of nasal polyps). Bernstein, J.M., Gorfien, J., Noble, B., Yankaskas, J.R. J. Allergy Clin. Immunol. (1997) [Pubmed]
  4. Nasal mucosal immunoexpression of the mast cell chemoattractants TGF-beta, eotaxin, and stem cell factor and their receptors in allergic rhinitis. Salib, R.J., Kumar, S., Wilson, S.J., Howarth, P.H. J. Allergy Clin. Immunol. (2004) [Pubmed]
  5. Role of the dermonecrotic toxin of Bordetella bronchiseptica in the pathogenesis of respiratory disease in swine. Brockmeier, S.L., Register, K.B., Magyar, T., Lax, A.J., Pullinger, G.D., Kunkle, R.A. Infect. Immun. (2002) [Pubmed]
  6. Gastrin-releasing peptide in human nasal mucosa. Baraniuk, J.N., Lundgren, J.D., Goff, J., Peden, D., Merida, M., Shelhamer, J., Kaliner, M. J. Clin. Invest. (1990) [Pubmed]
  7. Pathophysiology of rhinitis. Lactoferrin and lysozyme in nasal secretions. Raphael, G.D., Jeney, E.V., Baraniuk, J.N., Kim, I., Meredith, S.D., Kaliner, M.A. J. Clin. Invest. (1989) [Pubmed]
  8. Carcinogenicity of methylated derivatives of N-nitrosodiethylamine and related compounds in Sprague-Dawley rats. Lijinsky, W., Taylor, H.W. J. Natl. Cancer Inst. (1979) [Pubmed]
  9. Cytokine messenger RNA expression for IL-3, IL-4, IL-5, and granulocyte/macrophage-colony-stimulating factor in the nasal mucosa after local allergen provocation: relationship to tissue eosinophilia. Durham, S.R., Ying, S., Varney, V.A., Jacobson, M.R., Sudderick, R.M., Mackay, I.S., Kay, A.B., Hamid, Q.A. J. Immunol. (1992) [Pubmed]
  10. Glucocorticoids decrease c-fos expression in human nasal polyps in vivo. Baraniuk, J.N., Wong, G., Ali, M., Sabol, M., Troost, T. Thorax (1998) [Pubmed]
  11. Histamine content, synthesis and degradation in human nasal mucosa. Abe, Y., Ogino, S., Irifune, M., Imamura, I., Fukui, H., Wada, H., Matsunaga, T. Clin. Exp. Allergy (1993) [Pubmed]
  12. Long-term results after laser turbinectomy. Lippert, B.M., Werner, J.A. Lasers in surgery and medicine. (1998) [Pubmed]
  13. The effect of formaldehyde exposure upon the mononuclear phagocyte system of mice. Adams, D.O., Hamilton, T.A., Lauer, L.D., Dean, J.H. Toxicol. Appl. Pharmacol. (1987) [Pubmed]
  14. Carbon dioxide laser turbinate surgery for chronic obstructive rhinitis. Testa, B., Mesolella, M., Squeglia, C., Testa, D., Motta, G. Lasers in surgery and medicine. (2000) [Pubmed]
  15. Expression of connexin 45 in the olfactory system. Zhang, C., Restrepo, D. Brain Res. (2002) [Pubmed]
  16. Chitosan as a nasal delivery system: the effect of chitosan solutions on in vitro and in vivo mucociliary transport rates in human turbinates and volunteers. Aspden, T.J., Mason, J.D., Jones, N.S., Lowe, J., Skaugrud, O., Illum, L. Journal of pharmaceutical sciences. (1997) [Pubmed]
  17. Comparison of avian cell substrates for propagating subtype C avian metapneumovirus. Kong, B.W., Foster, L.K., Foster, D.N. Virus Res. (2006) [Pubmed]
  18. Responses of resistance and capacitance vessels in human nasal mucosa to beta-receptor agonists. Konno, A., Terada, N., Okamoto, Y. ORL J. Otorhinolaryngol. Relat. Spec. (1987) [Pubmed]
  19. Increased expression of IL-4, IL-5, IFN-gamma, IL-6, IL-8, and TGF-beta mRNAs in maxillary mucosa of patients with chronic sinusitis. Min, Y.G., Lee, C.H., Rhee, C.S., Hong, S.K., Kwon, S.H. American journal of rhinology. (1999) [Pubmed]
  20. Late-phase airway reaction and inflammation. Dolovich, J., Hargreave, F.E., Jordana, M., Denburg, J. J. Allergy Clin. Immunol. (1989) [Pubmed]
  21. Synthesis of interleukin-1 alpha, interleukin-6, and interleukin-8 by cultured human nasal epithelial cells. Kenney, J.S., Baker, C., Welch, M.R., Altman, L.C. J. Allergy Clin. Immunol. (1994) [Pubmed]
  22. Effect of clindamycin on intracellular replication, protein synthesis, and infectivity of Toxoplasma gondii. Blais, J., Tardif, C., Chamberland, S. Antimicrob. Agents Chemother. (1993) [Pubmed]
  23. Expression and localization of the inducible isoform of nitric oxide synthase in nasal polyp epithelium. Watkins, D.N., Lewis, R.H., Basclain, K.A., Fisher, P.H., Peroni, D.J., Garlepp, M.J., Thompson, P.J. Clin. Exp. Allergy (1998) [Pubmed]
  24. Characterization and autoradiographic localization of histamine H1 receptors in human nasal turbinates. Okayama, M., Baraniuk, J.N., Hausfeld, J.N., Merida, M., Kaliner, M.A. J. Allergy Clin. Immunol. (1992) [Pubmed]
  25. In vivo detection of a novel macrophage-derived protein involved in the regulation of nasal mucus-like glycoconjugate secretion. Sperber, K., Sylvester, C., Gollub, E., Goswami, S., Kalb, T.H., Druce, H., Rutledge, J., Marom, Z. J. Allergy Clin. Immunol. (1993) [Pubmed]
  26. Localization of histamine N-methyltransferase messenger RNA in human nasal mucosa. Okayama, M., Yamauchi, K., Sekizawa, K., Okayama, H., Sasaki, H., Inamura, N., Maeyama, K., Watanabe, T., Takishima, T., Shirato, K. J. Allergy Clin. Immunol. (1995) [Pubmed]
  27. Expression of IL-16 in allergen-induced late-phase nasal responses and relation to topical glucocorticosteroid treatment. Laberge, S., Durham, S.R., Ghaffar, O., Rak, S., Center, D.M., Jacobson, M., Hamid, Q. J. Allergy Clin. Immunol. (1997) [Pubmed]
  28. A double-blind, placebo controlled, dose ranging study to evaluate the safety and biological efficacy of the lipid-DNA complex GR213487B in the nasal epithelium of adult patients with cystic fibrosis. Knowles, M.R., Noone, P.G., Hohneker, K., Johnson, L.G., Boucher, R.C., Efthimiou, J., Crawford, C., Brown, R., Schwartzbach, C., Pearlman, R. Hum. Gene Ther. (1998) [Pubmed]
  29. Immunohistochemical localization of nitric oxide synthase activity in upper respiratory epithelium. Rosbe, K.W., Mims, J.W., Prazma, J., Petrusz, P., Rose, A., Drake, A.F. Laryngoscope (1996) [Pubmed]
  30. Immunohistochemical analysis of steroid hormone receptors in nasopharyngeal angiofibromas. Gatalica, Z. Cancer Lett. (1998) [Pubmed]
  31. Mucin mRNA expression in normal and vasomotor inferior turbinates. Aust, M.R., Madsen, C.S., Jennings, A., Kasperbauer, J.L., Gendler, S.J. American journal of rhinology. (1997) [Pubmed]
  32. Expression of mRNA of trefoil factor peptides in human nasal mucosa. Lee, S.H., Lee, S.H., Oh, B.H., Lee, H.M., Choi, J.O., Jung, K.Y. Acta Otolaryngol. (2001) [Pubmed]
  33. Immunohistochemical expression of VEGF and VEGF receptors in nasal polyps as compared to normal turbinate mucosa. Wittekindt, C., Hess, A., Bloch, W., Sultanie, S., Michel, O. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. (2002) [Pubmed]
  34. Interleukin-13 expression in the nasal mucosa of perennial allergic rhinitis. Pawankar, R.U., Okuda, M., Hasegawa, S., Suzuki, K., Yssel, H., Okubo, K., Okumura, K., Ra, C. Am. J. Respir. Crit. Care Med. (1995) [Pubmed]
  35. RANTES in human allergen-induced rhinitis: cellular source and relation to tissue eosinophilia. Rajakulasingam, K., Hamid, Q., O'Brien, F., Shotman, E., Jose, P.J., Williams, T.J., Jacobson, M., Barkans, J., Durham, S.R. Am. J. Respir. Crit. Care Med. (1997) [Pubmed]
  36. Blindness secondary to steroid injections into the nasal turbinates. Byers, B. Arch. Ophthalmol. (1979) [Pubmed]
  37. Local production and detection of (specific) IgE in nasal B-cells and plasma cells of allergic rhinitis patients. KleinJan, A., Vinke, J.G., Severijnen, L.W., Fokkens, W.J. Eur. Respir. J. (2000) [Pubmed]
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