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MeSH Review

Hyperlipoproteinemia Type III

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Disease relevance of Hyperlipoproteinemia Type III


High impact information on Hyperlipoproteinemia Type III


Chemical compound and disease context of Hyperlipoproteinemia Type III


Biological context of Hyperlipoproteinemia Type III


Anatomical context of Hyperlipoproteinemia Type III


Gene context of Hyperlipoproteinemia Type III


Analytical, diagnostic and therapeutic context of Hyperlipoproteinemia Type III


  1. Familial apolipoprotein E deficiency and type III hyperlipoproteinemia due to a premature stop codon in the apolipoprotein E gene. Lohse, P., Brewer, H.B., Meng, M.S., Skarlatos, S.I., LaRosa, J.C., Brewer, H.B. J. Lipid Res. (1992) [Pubmed]
  2. Apolipoprotein E3-Leiden. A new variant of human apolipoprotein E associated with familial type III hyperlipoproteinemia. Havekes, L., de Wit, E., Leuven, J.G., Klasen, E., Utermann, G., Weber, W., Beisiegel, U. Hum. Genet. (1986) [Pubmed]
  3. Relationship between cholesteryl ester transfer activity and high density lipoprotein composition in hyperlipidemic patients. Sparks, D.L., Frohlich, J., Lacko, A.G., Pritchard, P.H. Atherosclerosis (1989) [Pubmed]
  4. Fat loading experiments with the vitamins A and E suggest that in postprandial lipemia transfer/diffusion of chylomicron lipids to VLDL contributes to beta-VLDL formation. Demacker, P.N., Bredie, S.J., Hectors, M.P., Stalenhoef, A.F. Atherosclerosis (1998) [Pubmed]
  5. Expression of type III hyperlipoproteinemia in patients homozygous for apolipoprotein E-2 is modulated by lipoprotein lipase and postprandial hyperinsulinemia. Brümmer, D., Evans, D., Berg, D., Greten, H., Beisiegel, U., Mann, W.A. J. Mol. Med. (1998) [Pubmed]
  6. Myelomatosis with type III hyperlipoproteinemia: clinical and metabolic studies. Cortese, C., Lewis, B., Miller, N.E., Peyman, M.A., Rao, S.N., Slavin, B., Sule, U., Turner, P.R., Utermann, G., Wing, A.J., Weight, M., Wootton, R. N. Engl. J. Med. (1982) [Pubmed]
  7. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Mahley, R.W. Science (1988) [Pubmed]
  8. High-field 13C NMR Studies of certain normal and abnormal human plasma lipoproteins. Hamilton, J.A., Oppenheimer, N.J., Addleman, R., Clouse, A.O., Cordes, E.H., Steiner, P.M., Glueck, C.J. Science (1976) [Pubmed]
  9. Type III hyperlipoproteinemia and spontaneous atherosclerosis in mice resulting from gene replacement of mouse Apoe with human Apoe*2. Sullivan, P.M., Mezdour, H., Quarfordt, S.H., Maeda, N. J. Clin. Invest. (1998) [Pubmed]
  10. Type III hyperlipoproteinemic phenotype in transgenic mice expressing dysfunctional apolipoprotein E. Fazio, S., Lee, Y.L., Ji, Z.S., Rall, S.C. J. Clin. Invest. (1993) [Pubmed]
  11. Cholesterol net transport, esterification, and transfer in human hyperlipidemic plasma. Fielding, P.E., Fielding, C.J., Havel, R.J., Kane, J.P., Tun, P. J. Clin. Invest. (1983) [Pubmed]
  12. Type III hyperlipoproteinemia: paradoxical hypolipidemic response to estrogen. Kushwaha, R.S., Hazzard, W.R., Gagne, C., Chait, A., Albers, J.J. Ann. Intern. Med. (1977) [Pubmed]
  13. Role of apolipoprotein E in the lipolytic conversion of beta-very low density lipoproteins to low density lipoproteins in type III hyperlipoproteinemia. Ehnholm, C., Mahley, R.W., Chappell, D.A., Weisgraber, K.H., Ludwig, E., Witztum, J.L. Proc. Natl. Acad. Sci. U.S.A. (1984) [Pubmed]
  14. Novel mechanism for defective receptor binding of apolipoprotein E2 in type III hyperlipoproteinemia. Dong, L.M., Parkin, S., Trakhanov, S.D., Rupp, B., Simmons, T., Arnold, K.S., Newhouse, Y.M., Innerarity, T.L., Weisgraber, K.H. Nat. Struct. Biol. (1996) [Pubmed]
  15. Hypolipidemic and hyperlipidemic phenotypes in transgenic mice expressing human apolipoprotein E2. Huang, Y., Schwendner, S.W., Rall, S.C., Mahley, R.W. J. Biol. Chem. (1996) [Pubmed]
  16. Atypical familial dysbetalipoproteinemia associated with apolipoprotein phenotype E3/3. Havel, R.J., Kotite, L., Kane, J.P., Tun, P., Bersot, T. J. Clin. Invest. (1983) [Pubmed]
  17. Radioimmunoassay of human arginine-rich apolipoprotein, apoprotein E. Concentration in blood plasma and lipoproteins as affected by apoprotein E-3 deficiency. Havel, R.J., Kotite, L., Vigne, J.L., Kane, J.P., Tun, P., Phillips, N., Chen, G.C. J. Clin. Invest. (1980) [Pubmed]
  18. Patients with apoE3 deficiency (E2/2, E3/2, and E4/2) who manifest with hyperlipidemia have increased frequency of an Asn 291-->Ser mutation in the human LPL gene. Zhang, H., Reymer, P.W., Liu, M.S., Forsythe, I.J., Groenemeyer, B.E., Frohlich, J., Brunzell, J.D., Kastelein, J.J., Hayden, M.R., Ma, Y. Arterioscler. Thromb. Vasc. Biol. (1995) [Pubmed]
  19. Capillary electrophoretic detection in apolipoprotein E genotyping. Bekers, O., op den Buijsch, R.A., de Vries, J.E., Wijnen, P.A., van Dieijen-Visser, M.P. Electrophoresis (2002) [Pubmed]
  20. Lovastatin therapy in familial dysbetalipoproteinemia: effects on kinetics of apolipoprotein B. Vega, G.L., East, C., Grundy, S.M. Atherosclerosis (1988) [Pubmed]
  21. Adipose tissue lipoprotein lipase activity in type III hyperlipoproteinemia. Goldberg, A.P., Applebaum-Bowden, D.M., Hazzard, W.R. Metab. Clin. Exp. (1979) [Pubmed]
  22. Apolipoprotein gene cluster on chromosome 19. Definite localization of the APOC2 gene and the polymorphic Hpa I site associated with type III hyperlipoproteinemia. Smit, M., van der Kooij-Meijs, E., Frants, R.R., Havekes, L., Klasen, E.C. Hum. Genet. (1988) [Pubmed]
  23. Lipoprotein lipase compensates for the defective function of apo E variants in vitro by interacting with proteoglycans and lipoprotein receptors. Mann, W.A., Meyer, N., Berg, D., Greten, H., Beisiegel, U. Atherosclerosis (1999) [Pubmed]
  24. Detection of missense mutations in the genes for lipoprotein lipase and hepatic triglyceride lipase in patients with dyslipidemia undergoing coronary angiography. Moennig, G., Wiebusch, H., Enbergs, A., Dorszewski, A., Kerber, S., Schulte, H., Vielhauer, C., Haverkamp, W., Assmann, G., Breithardt, G., Funke, H. Atherosclerosis (2000) [Pubmed]
  25. Exact localization of the familial dysbetalipoproteinemia associated HpaI restriction site in the promoter region of the APOC1 gene. Smit, M., van der Kooij-Meijs, E., Woudt, L.P., Havekes, L.M., Frants, R.R. Biochem. Biophys. Res. Commun. (1988) [Pubmed]
  26. Effects of vitamin E and HMG-CoA reductase inhibition on cholesteryl ester transfer protein and lecithin-cholesterol acyltransferase in hypercholesterolemia. Napoli, C., Leccese, M., Palumbo, G., de Nigris, F., Chiariello, P., Zuliani, P., Somma, P., Di Loreto, M., De Matteis, C., Cacciatore, F., Abete, P., Liguori, A., Chiariello, M., D'Armiento, F.P. Coron. Artery Dis. (1998) [Pubmed]
  27. Type III hyperlipoproteinemia: defective metabolism of an abnormal apolipoprotein E. Gregg, R.E., Zech, L.A., Schaefer, E.J., Brewer, H.B. Science (1981) [Pubmed]
  28. Type III hyperlipoproteinemia: diagnosis in whole plasma by apolipoprotein-E immunoassay. Kushwaha, R.S., Hazzard, W.R., Wahl, P.W., Hoover, J.J. Ann. Intern. Med. (1977) [Pubmed]
  29. Long-term treatment of type III hyperlipoproteinemia with clofibrate. Stuyt, P.M., Demacker, P.N., Van't Laar, A. Atherosclerosis (1981) [Pubmed]
  30. Effects of plasmapheresis on familial type III hyperlipoproteinemia associated with glomerular lipidosis, nephrotic syndrome and diabetes mellitus. Suzaki, K., Kobori, S., Ueno, S., Uehara, M., Kayashima, T., Takeda, H., Fukuda, S., Takahashi, K., Nakamura, N., Uzawa, H. Atherosclerosis (1990) [Pubmed]
  31. Pancreatitis, familial hypertriglyceridemia, and pregnancy. Glueck, C.J., Christopher, C., Mishkel, M.A., Tsang, R.C., Mellies, M.J. Am. J. Obstet. Gynecol. (1980) [Pubmed]
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