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Disease relevance of Hypertriglyceridemia


Psychiatry related information on Hypertriglyceridemia


High impact information on Hypertriglyceridemia


Chemical compound and disease context of Hypertriglyceridemia


Biological context of Hypertriglyceridemia


Anatomical context of Hypertriglyceridemia


Gene context of Hypertriglyceridemia


Analytical, diagnostic and therapeutic context of Hypertriglyceridemia


  1. Positional cloning of the combined hyperlipidemia gene Hyplip1. Bodnar, J.S., Chatterjee, A., Castellani, L.W., Ross, D.A., Ohmen, J., Cavalcoli, J., Wu, C., Dains, K.M., Catanese, J., Chu, M., Sheth, S.S., Charugundla, K., Demant, P., West, D.B., de Jong, P., Lusis, A.J. Nat. Genet. (2002) [Pubmed]
  2. Inheritance of apolipoprotein C-II deficiency with hypertriglyceridemia and pancreatitis. Cox, D.W., Breckenridge, W.C., Little, J.A. N. Engl. J. Med. (1978) [Pubmed]
  3. Mutations of the cystic fibrosis gene in patients with chronic pancreatitis. Sharer, N., Schwarz, M., Malone, G., Howarth, A., Painter, J., Super, M., Braganza, J. N. Engl. J. Med. (1998) [Pubmed]
  4. Regulation of lipoprotein lipase in the diabetic rat. Tavangar, K., Murata, Y., Pedersen, M.E., Goers, J.F., Hoffman, A.R., Kraemer, F.B. J. Clin. Invest. (1992) [Pubmed]
  5. An abnormal triglyceride-rich lipoprotein containing excess sialylated apolipoprotein C-III. Holdsworth, G., Stocks, J., Dodson, P., Galton, D.J. J. Clin. Invest. (1982) [Pubmed]
  6. Sex difference in the effects of sociocultural status on diabetes and cardiovascular risk factors in Mexican Americans. The San Antonio Heart Study. Stern, M.P., Rosenthal, M., Haffner, S.M., Hazuda, H.P., Franco, L.J. Am. J. Epidemiol. (1984) [Pubmed]
  7. A case of alcoholic liver injury with an unusual polyacrylamide-gel disc-electrophoretic pattern of serum lipoproteins. Watanabe, M., Taketa, K., Fujii, K., Fujii, C., Kono, H. Acta Med. Okayama (1979) [Pubmed]
  8. Delayed severe hypertriglyceridemia from tamoxifen. Kanel, K.T., Wolmark, N., Thompson, P.D. N. Engl. J. Med. (1997) [Pubmed]
  9. Changes in plasma lipids and lipoproteins during isotretinoin therapy for acne. Bershad, S., Rubinstein, A., Paterniti, J.R., Le, N.A., Poliak, S.C., Heller, B., Ginsberg, H.N., Fleischmajer, R., Brown, W.V. N. Engl. J. Med. (1985) [Pubmed]
  10. Increase in lipoprotein lipase during clofibrate treatment of hypertriglyceridemia in patients on hemodialysis. Goldberg, A.P., Applebaum-Bowden, D.M., Bierman, E.L., Hazzard, W.R., Haas, L.B., Sherrard, D.J., Brunzell, J.D., Huttunen, J.K., Ehnholm, C., Nikkila, E.A. N. Engl. J. Med. (1979) [Pubmed]
  11. Hypertriglyceridemia associated with deficiency of apolipoprotein C-II. Breckenridge, W.C., Little, J.A., Steiner, G., Chow, A., Poapst, M. N. Engl. J. Med. (1978) [Pubmed]
  12. Hypertriglyceridemia as a result of human apo CIII gene expression in transgenic mice. Ito, Y., Azrolan, N., O'Connell, A., Walsh, A., Breslow, J.L. Science (1990) [Pubmed]
  13. Selective deficiency of hepatic triglyceride lipase in uremic patients. Mordasini, R., Frey, F., Flury, W., Klose, G., Greten, H. N. Engl. J. Med. (1977) [Pubmed]
  14. Effect of oxandrolone treatment on the activity of lipoprotein lipase, hepatic lipase and phospholipase A1 of human postheparin plasma. Ehnholm, C., Huttunen, J.K., Kinnunen, P.J., Miettinen, T.A., Nikkilä, E.A. N. Engl. J. Med. (1975) [Pubmed]
  15. Influence of gemfibrozil and clofibrate on metabolism of cholesterol and plasma triglycerides in man. Kesäniemi, Y.A., Grundy, S.M. JAMA (1984) [Pubmed]
  16. Effect of niacin on lipid and lipoprotein levels and glycemic control in patients with diabetes and peripheral arterial disease: the ADMIT study: A randomized trial. Arterial Disease Multiple Intervention Trial. Elam, M.B., Hunninghake, D.B., Davis, K.B., Garg, R., Johnson, C., Egan, D., Kostis, J.B., Sheps, D.S., Brinton, E.A. JAMA (2000) [Pubmed]
  17. Efficacy and safety of a new HMG-CoA reductase inhibitor, atorvastatin, in patients with hypertriglyceridemia. Bakker-Arkema, R.G., Davidson, M.H., Goldstein, R.J., Davignon, J., Isaacsohn, J.L., Weiss, S.R., Keilson, L.M., Brown, W.V., Miller, V.T., Shurzinske, L.J., Black, D.M. JAMA (1996) [Pubmed]
  18. PPAR delta: a dagger in the heart of the metabolic syndrome. Barish, G.D., Narkar, V.A., Evans, R.M. J. Clin. Invest. (2006) [Pubmed]
  19. Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes. Weinstock, P.H., Bisgaier, C.L., Aalto-Setälä, K., Radner, H., Ramakrishnan, R., Levak-Frank, S., Essenburg, A.D., Zechner, R., Breslow, J.L. J. Clin. Invest. (1995) [Pubmed]
  20. Lipid and lipoprotein abnormalities in alcoholic liver disease. Sabesin, S.M. Circulation (1981) [Pubmed]
  21. Linkage of the metabolic syndrome to 1q23-q31 in Hispanic families: the Insulin Resistance Atherosclerosis Study Family Study. Langefeld, C.D., Wagenknecht, L.E., Rotter, J.I., Williams, A.H., Hokanson, J.E., Saad, M.F., Bowden, D.W., Haffner, S., Norris, J.M., Rich, S.S., Mitchell, B.D. Diabetes (2004) [Pubmed]
  22. Probing the pathways of chylomicron and HDL metabolism using adenovirus-mediated gene transfer. Zannis, V.I., Chroni, A., Kypreos, K.E., Kan, H.Y., Cesar, T.B., Zanni, E.E., Kardassis, D. Curr. Opin. Lipidol. (2004) [Pubmed]
  23. Inhibition of adipogenesis and development of glucose intolerance by soluble preadipocyte factor-1 (Pref-1). Lee, K., Villena, J.A., Moon, Y.S., Kim, K.H., Lee, S., Kang, C., Sul, H.S. J. Clin. Invest. (2003) [Pubmed]
  24. Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy. Petersen, K.F., Oral, E.A., Dufour, S., Befroy, D., Ariyan, C., Yu, C., Cline, G.W., DePaoli, A.M., Taylor, S.I., Gorden, P., Shulman, G.I. J. Clin. Invest. (2002) [Pubmed]
  25. Biliary lipid composition in normo- and hyperlipoproteinemia. Ahlberg, J., Angelin, B., Einarsson, K., Hellström, K., Leijd, B. Gastroenterology (1980) [Pubmed]
  26. Regulation of lipoprotein lipase by glucose in primary cultures of isolated human adipocytes. Relevance to hypertriglyceridemia of diabetes. Kern, P.A., Mandic, A., Eckel, R.H. Diabetes (1987) [Pubmed]
  27. Mice lacking thioredoxin-interacting protein provide evidence linking cellular redox state to appropriate response to nutritional signals. Hui, T.Y., Sheth, S.S., Diffley, J.M., Potter, D.W., Lusis, A.J., Attie, A.D., Davis, R.A. J. Biol. Chem. (2004) [Pubmed]
  28. Human ApoA-II inhibits the hydrolysis of HDL triglyceride and the decrease of HDL size induced by hypertriglyceridemia and cholesteryl ester transfer protein in transgenic mice. Zhong, S., Goldberg, I.J., Bruce, C., Rubin, E., Breslow, J.L., Tall, A. J. Clin. Invest. (1994) [Pubmed]
  29. Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse. Ueki, K., Kondo, T., Tseng, Y.H., Kahn, C.R. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  30. Inhibition of cardiac lipoprotein utilization by transgenic overexpression of Angptl4 in the heart. Yu, X., Burgess, S.C., Ge, H., Wong, K.K., Nassem, R.H., Garry, D.J., Sherry, A.D., Malloy, C.R., Berger, J.P., Li, C. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
  31. Molecular cloning and characteristics of a new apolipoprotein C-II mutant identified in three unrelated individuals with hypercholesterolemia and hypertriglyceridemia. Pullinger, C.R., Zysow, B.R., Hennessy, L.K., Frost, P.H., Malloy, M.J., Kane, J.P. Hum. Mol. Genet. (1993) [Pubmed]
  32. A novel genetic variant in the apolipoprotein A5 gene is associated with hypertriglyceridemia. Kao, J.T., Wen, H.C., Chien, K.L., Hsu, H.C., Lin, S.W. Hum. Mol. Genet. (2003) [Pubmed]
  33. An analysis of genotype effects and their interactions by using the apolipoprotein E polymorphism and longitudinal data. Gueguen, R., Visvikis, S., Steinmetz, J., Siest, G., Boerwinkle, E. Am. J. Hum. Genet. (1989) [Pubmed]
  34. Hypertriglyceridemia in lecithin-cholesterol acyltransferase-deficient mice is associated with hepatic overproduction of triglycerides, increased lipogenesis, and improved glucose tolerance. Ng, D.S., Xie, C., Maguire, G.F., Zhu, X., Ugwu, F., Lam, E., Connelly, P.W. J. Biol. Chem. (2004) [Pubmed]
  35. Hypertriglyceridemia in different degrees of glucose intolerance in a Finnish population-based study. Salomaa, V.V., Tuomilehto, J., Jauhiainen, M., Korhonen, H.J., Stengård, J., Uusitupa, M., Pitkanen, M., Penttila, I. Diabetes Care (1992) [Pubmed]
  36. LDL physical and chemical properties in familial combined hyperlipidemia. Hokanson, J.E., Krauss, R.M., Albers, J.J., Austin, M.A., Brunzell, J.D. Arterioscler. Thromb. Vasc. Biol. (1995) [Pubmed]
  37. Estrogen effects on triglyceride metabolism in analbuminemic rats. Shearer, G.C., Joles, J.A., Jones, H., Walzem, R.L., Kaysen, G.A. Kidney Int. (2000) [Pubmed]
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