Disease relevance of Aotus trivirgatus

• In Saimiri sciureus (24 subjects) and Aotus trivirgatus (11 subjects), parasite clearance from the peripheral blood averaged 3 days after initiating chloroquine therapy (total dose of 25 mg base/kg body weight over 3 days or single dose of 10 mg base/kg [1].
• Topical application of a single dose of 1.0 mg prostaglandin F2 alpha (PGF2 alpha) onto the cornea of five trained owl monkeys (Aotus trivirgatus) caused a prolonged and highly significant ocular hypotony [2].

High impact information on Aotus trivirgatus

• These data suggest that the functional 1,25-(OH)2D3-receptor phenotype of the owl monkey, Aotus trivirgatus, is more closely aligned to the catarrhine phenotype than are those of other platyrrhines in the families Cebidae and Callitricidae [3].
• Studies were undertaken to determine whether rheumatoid factor (RF) was present in immune human and Aotus trivirgatus monkey sera which inhibited Plasmodium falciparum schizonts in vitro and to determine whether RF could be responsible for or contribute to merozoite agglutination in the parasite inhibition test [4].
• The location of substance P (SP) in the lateral cervical nucleus (LCN) of monkeys (Aotus trivirgatus), cats, and rats was investigated with immunohistochemical methods [5].
• Reverse transcriptase-polymerase chain reaction amplification and partial sequence of T helper 1- and T helper 2-type lymphokine genes from the owl monkey (Aotus trivirgatus) [6].
• The present study examined with quantitative immunohistochemical methods the presence of glutamate in spinothalamic tract terminals of owl monkeys (Aotus trivirgatus) [7].

Biological context of Aotus trivirgatus

• Plasma concentrations of oestradiol-17 beta, oestrone, progesterone and testosterone during the ovarian cycle of the owl monkey (Aotus trivirgatus) [8].

Anatomical context of Aotus trivirgatus

• Plasmodium falciparum-parasitized erythrocytes obtained from infected owl monkeys (Aotus trivirgatus) and stored in the frozen state retain both the capacity to incorporate 14C isoleucine into protein and to infect animals [9].

Associations of Aotus trivirgatus with chemical compounds

• Plasmodium falciparum and Plasmodium vivax infections in the owl monkey (Aotus trivirgatus). II. Responses to chloroquine, quinine, and pyrimethamine [10].
• Effectiveness of allopurinol against Leishmania braziliensis panamensis in Aotus trivirgatus [11].
• 6 Aotus trivirgatus monkeys, which had all spontaneously recovered from an experimentally induced Plasmodium falciparum infection, were included in a clinical study concentrating on possible adverse reactions caused by a vaccine using late schizonts and merozoites as an antigen a synthetic compound, CP-20,961, as an adjuvant [12].
• Erythrocyte characteristics in vitamin E-responsive anemia of the owl monkey (Aotus trivirgatus) [13].
• Six Aotus trivirgatus monkeys were included in a clinical study to compare the adverse reactions caused by a Plasmodium falciparum antigen and 2 adjuvants, a lipoidal amine, CP-20,961, and a muramyl dipeptide derivative, [B30]-MDP [14].

Gene context of Aotus trivirgatus

• Calbindin D-28K in the dopaminergic mesocortical projection of a monkey (Aotus trivirgatus) [15].
• Two distinct forms of beta 2-microglobulin in different races of owl monkey (Aotus trivirgatus) [16].
• We have mapped the albumin locus (ALB) in the owl monkey, Aotus trivirgatus, using a cloned human albumin gene probe, pcHSA 33-1 [17].

References