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Chemical Compound Review

RHODAMINE 6G     ethyl2-(6-ethylamino-3- ethylimino-2,7...

Synonyms: Rhodanine 6GDN, SureCN1495836, SureCN4817749, CBDivE_013147, SureCN10028465, ...
 
 
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Disease relevance of NSC47732

  • The accumulation of rhodamine-6G-labeled leukocytes and the number of nonperfused sinusoids (NPS) were monitored (by intravital microscopy) in mouse liver for 1 hour after a 15-minute period of normothermic intestinal ischemia [1].
 

High impact information on NSC47732

  • In view of the known maternal inheritance of mitochondria we have assessed their involvement in Mta expression using the mitochondria specific poison Rhodamine 6G (R6G) [2].
  • The exceptional R6G-treated hybrids that continued to express the BALB/c Mta phenotype likewise contained only BALB/c mtDNA [3].
  • Leukocytes were fluorescently labeled with rhodamine-6G so that leukocyte-leukocyte interactions could be studied in whole blood [4].
  • Luminescence and photoexcitation spectra show that energy transfer from the metal complex to R6G occurs in the films [5].
  • Although the fluorescence spectra in the 330-nm-, 850-nm- and 250-microm-sized channels agreed with one another, the fluorescent decays in the nanometer-sized channels were faster for R6G and SR101 and slower for RB than the respective decays in the 250-microm-sized channels [6].
 

Biological context of NSC47732

 

Anatomical context of NSC47732

  • Second, the cationic dye rhodamine 6G (R6G) enters cultured cells by a potential-driven process, and single R6G molecules are observed as intense photon bursts when they move in and out of the intracellular laser beam [12].
  • METHODS: Thirty patients with complicated bile duct stones were treated perorally with a flashlamp-pulsed Rhodamine-6G dye laser and an automatic stone-tissue discrimination system [13].
  • AO and Rh6G induced leukocyte rolling/sticking in postcapillary venules and arterioles when exposed to high light energy levels [14].
  • Eighteen patients with giant or impacted common bile duct stones refractory to standard treatment techniques were treated via the endoscopic retrograde route using a rhodamine-6G dye laser with an integrated stone-tissue detection system [15].
  • The R6G efflux from oocytes was accelerated at the MII stage more than at the GV stage [16].
 

Associations of NSC47732 with other chemical compounds

 

Gene context of NSC47732

  • P-gp inhibitors significantly blocked the R6G efflux from the MII oocytes, whereas the reagents were ineffective in the GV oocytes [16].
 

Analytical, diagnostic and therapeutic context of NSC47732

  • Laser lithotripsy using the rhodamine-6G dye laser plus stone-tissue detection system appears safe and effective and allows "blind" fragmentation of difficult common bile duct stones to be performed under radiologic control [15].
  • METHODS: Dye penetration depth was assessed histologically after the use of formulations containing rhodamine-6G-loaded microspheres dispersed into two different silicones [19].
  • Thus, the adsorbed amount of KWK per unit area at a given total KWK concentration, as determined by the centrifugation method, can be plotted against the fractions of R6G anisotropy decay components at the same KWK concentration to relate the anisotropy components to the absolute surface coverage [20].
  • The morphology of these films has been characterized by scanning electron microscopy (SEM), and their performance as surface-enhanced Raman scattering (SERS) substrates has been evaluated by using rhodamine 6G (R6G) as a probe molecule [21].
  • Comparisons between far-field Raman images of R6G-covered Ag particle aggregates with topographic images recorded using atomic force microscopy (AFM) indicate saturation effects due to resonance excitation [22].

References

  1. Role of Kupffer cells in gut ischemia/reperfusion-induced hepatic microvascular dysfunction in mice. Horie, Y., Wolf, R., Russell, J., Shanley, T.P., Granger, D.N. Hepatology (1997) [Pubmed]
  2. Mitochondria control expression of a murine cell surface antigen. Smith, R., Huston, M.M., Jenkins, R.N., Huston, D.P., Rich, R.R. Nature (1983) [Pubmed]
  3. Mitochondrial modulation of maternally transmitted antigen: analysis of cell hybrids. Huston, M.M., Smith, R., Hull, R., Huston, D.P., Rich, R.R. Proc. Natl. Acad. Sci. U.S.A. (1985) [Pubmed]
  4. Importance of L-selectin-dependent leukocyte-leukocyte interactions in human whole blood. Mitchell, D.J., Li, P., Reinhardt, P.H., Kubes, P. Blood (2000) [Pubmed]
  5. Multiply doped nanostructured silicate sol-gel thin films: spatial segregation of dopants, energy transfer, and distance measurements. Minoofar, P.N., Dunn, B.S., Zink, J.I. J. Am. Chem. Soc. (2005) [Pubmed]
  6. Nanochannels on a fused-silica microchip and liquid properties investigation by time-resolved fluorescence measurements. Hibara, A., Saito, T., Kim, H.B., Tokeshi, M., Ooi, T., Nakao, M., Kitamori, T. Anal. Chem. (2002) [Pubmed]
  7. Changes in membrane potential and membrane fluidity in Tetrahymena pyriformis in association with chemoreception of hydrophobic stimuli: fluorescence studies. Tanabe, H., Kurihara, K., Kobatake, Y. Biochemistry (1980) [Pubmed]
  8. P-selectin mediates platelet-endothelial cell interactions and reperfusion injury in the mouse liver in vivo. Khandoga, A., Biberthaler, P., Enders, G., Teupser, D., Axmann, S., Luchting, B., Hutter, J., Messmer, K., Krombach, F. Shock (2002) [Pubmed]
  9. Adsorption Characteristics and the Kinetics of the Cation Exchange of Rhodamine-6G with Na(+)-Montmorillonite. Gemeay, A.H. Journal of colloid and interface science. (2002) [Pubmed]
  10. The effect of papaverine on synaptosomal membrane potential. Covello, C., Bonofiglio, D., Mandalà, M., Martino, G. Boll. Soc. Ital. Biol. Sper. (1996) [Pubmed]
  11. Molecular determinants of the prothrombogenic and inflammatory phenotype assumed by the postischemic cerebral microcirculation. Ishikawa, M., Cooper, D., Russell, J., Salter, J.W., Zhang, J.H., Nanda, A., Granger, D.N. Stroke (2003) [Pubmed]
  12. Probing single molecules in single living cells. Byassee, T.A., Chan, W.C., Nie, S. Anal. Chem. (2000) [Pubmed]
  13. Peroral laser lithotripsy of difficult intrahepatic and extrahepatic bile duct stones: laser effectiveness using an automatic stone-tissue discrimination system. Jakobs, R., Maier, M., Kohler, B., Riemann, J.F. Am. J. Gastroenterol. (1996) [Pubmed]
  14. Intravital fluorescence microscopy: impact of light-induced phototoxicity on adhesion of fluorescently labeled leukocytes. Saetzler, R.K., Jallo, J., Lehr, H.A., Philips, C.M., Vasthare, U., Arfors, K.E., Tuma, R.F. J. Histochem. Cytochem. (1997) [Pubmed]
  15. Laser lithotripsy of difficult bile duct stones by means of a rhodamine-6G laser and an integrated automatic stone-tissue detection system. Ell, C., Hochberger, J., May, A., Fleig, W.E., Bauer, R., Mendez, L., Hahn, E.G. Gastrointest. Endosc. (1993) [Pubmed]
  16. Development of multidrug resistance type I P-glycoprotein function during in vitro maturation of porcine oocyte. Arai, M., Yamauchi, N., Fukuda, H., Soh, T., Hattori, M.A. Reprod. Toxicol. (2006) [Pubmed]
  17. Elimination of mitochondrial elements and improved viability in hybrid cells. Ziegler, M.L., Davidson, R.L. Somatic Cell Genet. (1981) [Pubmed]
  18. Ultrafast fluorescence resonance energy transfer in a micelle. Sahu, K., Ghosh, S., Mondal, S.K., Ghosh, B.C., Sen, P., Roy, D., Bhattacharyya, K. The Journal of chemical physics. (2006) [Pubmed]
  19. A new method to improve penetration depth of dyes into the follicular duct: potential application for laser hair removal. Sumian, C.C., Pitre, F.B., Gauthier, B.E., Bouclier, M., Mordon, S.R. J. Am. Acad. Dermatol. (1999) [Pubmed]
  20. Quantifying surface coverage of colloidal silica by a cationic peptide using a combined centrifugation/time-resolved fluorescence anisotropy approach. Tleugabulova, D., Brennan, J.D. Langmuir : the ACS journal of surfaces and colloids. (2006) [Pubmed]
  21. Designed fabrication of ordered porous au/ag nanostructured films for surface-enhanced Raman scattering substrates. Lu, L., Eychmüller, A., Kobayashi, A., Hirano, Y., Yoshida, K., Kikkawa, Y., Tawa, K., Ozaki, Y. Langmuir : the ACS journal of surfaces and colloids. (2006) [Pubmed]
  22. Large-area topography analysis and near-field Raman spectroscopy using bent fibre probes. Prikulis, J., Murty, K.V., Olin, H., Käll, M. Journal of microscopy. (2003) [Pubmed]
 
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