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Chemical Compound Review

Platycodin D     [(2S,3R,4S,5S)-3- [(2S,3R,4S,5R,6S)-5-[(2S...

Synonyms: CHEMBL1641859, CHEBI:70436, AR-1F4719, AR-1F4720, LS-193714, ...
 
 
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Disease relevance of Platycodin D

 

High impact information on Platycodin D

 

Biological context of Platycodin D

 

Anatomical context of Platycodin D

 

Associations of Platycodin D with other chemical compounds

 

Gene context of Platycodin D

References

  1. Cholesterol-lowering effect of platycodin D in hypercholesterolemic ICR mice. Zhao, H.L., Cho, K.H., Ha, Y.W., Jeong, T.S., Lee, W.S., Kim, Y.S. Eur. J. Pharmacol. (2006) [Pubmed]
  2. Saponins from platycodi radix ameliorate high fat diet-induced obesity in mice. Han, L.K., Zheng, Y.N., Xu, B.J., Okuda, H., Kimura, Y. J. Nutr. (2002) [Pubmed]
  3. Platycodin D-induced apoptosis through nuclear factor-kappaB activation in immortalized keratinocytes. Ahn, K.S., Hahn, B.S., Kwack, K., Lee, E.B., Kim, Y.S. Eur. J. Pharmacol. (2006) [Pubmed]
  4. Platycodin D and D3 isolated from the root of Platycodon grandiflorum modulate the production of nitric oxide and secretion of TNF-alpha in activated RAW 264.7 cells. Wang, C., Schuller Levis, G.B., Lee, E.B., Levis, W.R., Lee, d.a. .W., Kim, B.S., Park, S.Y., Park, E. Int. Immunopharmacol. (2004) [Pubmed]
  5. Inhibition of prostaglandin E2 production by platycodin D isolated from the root of Platycodon grandiflorum. Kim, Y.P., Lee, E.B., Kim, S.Y., Li, D., Ban, H.S., Lim, S.S., Shin, K.H., Ohuchi, K. Planta Med. (2001) [Pubmed]
  6. Stimulative effects of saponin from kikyo-to, a Japanese herbal medicine, on pancreatic exocrine secretion of conscious rats. Arai, I., Komatsu, Y., Hirai, Y., Shingu, K., Ida, Y., Yamaura, H., Yamamoto, T., Kuroiwa, Y., Sasaki, K., Taguchi, S. Planta Med. (1997) [Pubmed]
  7. Platycodin D and D3 increase airway mucin release in vivo and in vitro in rats and hamsters. Shin, C.Y., Lee, W.J., Lee, E.B., Choi, E.Y., Ko, K.H. Planta Med. (2002) [Pubmed]
  8. Requirement of the glycosyl parts in platycodin D to stimulate pancreatic exocrine secretion. Ida, Y., Hirai, Y., Kajimoto, T., Shingu, K., Miura, T., Kuwahara, N., Taguchi, S., Sasaki, K., Kuroiwa, Y., Yamamoto, T., Arai, I., Amagaya, S., Komatsu, Y. Bioorg. Med. Chem. Lett. (1998) [Pubmed]
  9. Enhancement and suppression in production of IgM-antibody in mice treated with purified saponins. Mita, A., Shida, R., Kasai, N., Shoji, J. Biomedicine / [publiée pour l'A.A.I.C.I.G.]. (1979) [Pubmed]
  10. Determination of the kinetic properties of platycodin D for the inhibition of pancreatic lipase using a 1,2-diglyceride-based colorimetric assay. Zhao, H.L., Kim, Y.S. Arch. Pharm. Res. (2004) [Pubmed]
 
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