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Chemical Compound Review

aminoacetone     1-aminopropan-2-one

Synonyms: AMINO-ACETONE, PRO007, CHEBI:17906, HMDB02134, ANW-45217, ...
 
 
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Disease relevance of C01888

 

High impact information on C01888

 

Biological context of C01888

 

Anatomical context of C01888

 

Associations of C01888 with other chemical compounds

 

Gene context of C01888

 

Analytical, diagnostic and therapeutic context of C01888

References

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  2. Potential therapeutic value of drugs inhibiting semicarbazide-sensitive amine oxidase: vascular cytoprotection in diabetes mellitus. Ekblom, J. Pharmacol. Res. (1998) [Pubmed]
  3. Purification and properties of aminoacetone synthetase from beef liver mitochondria. Fubara, B., Eckenrode, F., Tressel, T., Davis, L. J. Biol. Chem. (1986) [Pubmed]
  4. Semicarbazide-sensitive amine oxidase: current status and perspectives. Mátyus, P., Dajka-Halász, B., Földi, A., Haider, N., Barlocco, D., Magyar, K. Current medicinal chemistry. (2004) [Pubmed]
  5. Involvement of SSAO-mediated deamination in adipose glucose transport and weight gain in obese diabetic KKAy mice. Yu, P.H., Wang, M., Fan, H., Deng, Y., Gubisne-Haberle, D. Am. J. Physiol. Endocrinol. Metab. (2004) [Pubmed]
  6. 2-Bromoethylamine as a potent selective suicide inhibitor for semicarbazide-sensitive amine oxidase. Yu, P.H., Davis, B.A., Deng, Y. Biochem. Pharmacol. (2001) [Pubmed]
  7. Aerobic oxidation of aminoacetone, a threonine catabolite: iron catalysis and coupled iron release from ferritin. Dutra, F., Knudsen, F.S., Curi, D., Bechara, E.J. Chem. Res. Toxicol. (2001) [Pubmed]
  8. Potential inplications of endogenous aldehydes in beta-amyloid misfolding, oligomerization and fibrillogenesis. Chen, K., Maley, J., Yu, P.H. J. Neurochem. (2006) [Pubmed]
  9. Oxidative DNA damage induced by aminoacetone, an amino acid metabolite. Hiraku, Y., Sugimoto, J., Yamaguchi, T., Kawanishi, S. Arch. Biochem. Biophys. (1999) [Pubmed]
  10. Diabetes and semicarbazide-sensitive amine oxidase (SSAO) activity: a review. Obata, T. Life Sci. (2006) [Pubmed]
  11. Threonine catabolism in Trypanosoma brucei. Linstead, D.J., Klein, R.A., Cross, G.A. J. Gen. Microbiol. (1977) [Pubmed]
  12. L-Threonine dehydrogenase of chicken liver. Purification, characterization, and physiological significance. Aoyama, Y., Motokawa, Y. J. Biol. Chem. (1981) [Pubmed]
  13. The metabolism of aminoacetone to methylglyoxal by semicarbazide-sensitive amine oxidase in human umbilical artery. Lyles, G.A., Chalmers, J. Biochem. Pharmacol. (1992) [Pubmed]
  14. Semicarbazide-sensitive amine oxidase in aortic smooth muscle cells mediates synthesis of a methylglyoxal-AGE: implications for vascular complications in diabetes. Mathys, K.C., Ponnampalam, S.N., Padival, S., Nagaraj, R.H. Biochem. Biophys. Res. Commun. (2002) [Pubmed]
  15. Metabolites of the aminoacetone pathway in blood after exercise. Haralambie, G., Mössinger, M. Metab. Clin. Exp. (1980) [Pubmed]
  16. Dietary protein and amino acid levels alter threonine dehydrogenase activity in hepatic mitochondria of Gallus domesticus. Davis, A.J., Austic, R.E. J. Nutr. (1997) [Pubmed]
  17. Assessment of the deamination of aminoacetone, an endogenous substrate for semicarbazide-sensitive amine oxidase. Deng, Y., Yu, P.H. Anal. Biochem. (1999) [Pubmed]
  18. Aminoacetone metabolism by semicarbazide-sensitive amine oxidase in rat aorta. Lyles, G.A., Chalmers, J. Biochem. Pharmacol. (1995) [Pubmed]
 
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