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Chemical Compound Review

Granular blue     2-[4-[2-(4- carbamimidoylphenoxy) ethoxy]phe...

Synonyms: AC1MIVT9, 55368-30-4, 71431-29-3
This record was replaced with 3080833.
 
 
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Disease relevance of 2-[4-[2-(4-carbamimidoylphenoxy)ethoxy]phenyl]-1H-indole-6-carboximidamide

 

High impact information on 2-[4-[2-(4-carbamimidoylphenoxy)ethoxy]phenyl]-1H-indole-6-carboximidamide

 

Biological context of 2-[4-[2-(4-carbamimidoylphenoxy)ethoxy]phenyl]-1H-indole-6-carboximidamide

  • Previous studies have shown that developing neocortical neurons labeled in situ by retrograde axonal transport of the fluorescent dye Granular Blue can retain this dye for at least 2 months essentially without fading or leakage [7].
 

Anatomical context of 2-[4-[2-(4-carbamimidoylphenoxy)ethoxy]phenyl]-1H-indole-6-carboximidamide

 

Associations of 2-[4-[2-(4-carbamimidoylphenoxy)ethoxy]phenyl]-1H-indole-6-carboximidamide with other chemical compounds

  • Findings after injections of two different tracers in the same animal (bisbenzimide and 'true blue', Evans blue and 'granular blue') suggest that about 15% of the labeled neurons in the above areas distribute divergent axon collaterals to both the medulla and the spinal cord [13].
 

Gene context of 2-[4-[2-(4-carbamimidoylphenoxy)ethoxy]phenyl]-1H-indole-6-carboximidamide

 

Analytical, diagnostic and therapeutic context of 2-[4-[2-(4-carbamimidoylphenoxy)ethoxy]phenyl]-1H-indole-6-carboximidamide

  • In light microscopy, brown and granular blue stainings of chromogens revealing both antigens were easily identifiable and spatially separated in perikarya [15].

References

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  2. Selective extraction of small and large molecules from the cerebrospinal fluid by Purkinje neurons. Borges, L.F., Elliott, P.J., Gill, R., Iversen, S.D., Iversen, L.L. Science (1985) [Pubmed]
  3. Relay cells, not interneurons, of cat's lateral geniculate nucleus contain N-acetylaspartylglutamate. Xing, L.C., Tieman, S.B. J. Comp. Neurol. (1993) [Pubmed]
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  5. A small subpopulation of progesterone receptor-containing neurons in the guinea pig arcuate nucleus projects to the median eminence. Poulain, P., Warembourg, M., Jolivet, A. J. Neurosci. Res. (1990) [Pubmed]
  6. Origin of ascending and spinal pathways from the nucleus tegmenti pedunculopontinus in the rat. Spann, B.M., Grofova, I. J. Comp. Neurol. (1989) [Pubmed]
  7. Neonatal hippocampal neurons, retrogradely labeled with granular blue, survive intracerebral grafting and explantation to tissue culture. Tønder, N., Gaarskjaer, F.B., Sunde, N.A., Zimmer, J. Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale. (1986) [Pubmed]
  8. Funicular trajectories of brainstem neurons projecting to the lumbar spinal cord in the monkey (Macaca fascicularis): a retrograde labeling study. Carlton, S.M., Chung, J.M., Leonard, R.B., Willis, W.D. J. Comp. Neurol. (1985) [Pubmed]
  9. The distribution and origin of serotonin-containing fibers in the septal area: a combined immunohistochemical and fluorescent retrograde tracing study in the rat. Köhler, C., Chan-Palay, V., Steinbusch, H. J. Comp. Neurol. (1982) [Pubmed]
  10. Identification of serotonin and non-serotonin-containing neurons of the mid-brain raphe projecting to the entorhinal area and the hippocampal formation. A combined immunohistochemical and fluorescent retrograde tracing study in the rat brain. Köhler, C., Steinbusch, H. Neuroscience (1982) [Pubmed]
  11. Lateral septal projections onto tubero-infundibular neurons in the hypothalamus of the guinea pig. Varoqueaux, F., Poulain, P. Cell Tissue Res. (1994) [Pubmed]
  12. Serotonergic and non-serotonergic projections from the interpeduncular nucleus to the ventral hippocampus in the rat. Groenewegen, H.J., Steinbusch, H.W. Neurosci. Lett. (1984) [Pubmed]
  13. A direct projection from the ventromedial nucleus and retrochiasmatic area of the hypothalamus to the medulla and spinal cord of the rat. Swanson, L.W., Kuypers, H.G. Neurosci. Lett. (1980) [Pubmed]
  14. Labeling of neurons following intravenous injections of fluorescent tracers in mice. van der Krans, A., Hoogland, P.V. J. Neurosci. Methods (1983) [Pubmed]
  15. Neurons that express the AMPA receptor GluR2/3 subunits in suprachiasmatic nuclei of Syrian hamsters colocalize either vasoactive intestinal peptide, peptide histidine isoleucine or gastrin-releasing peptide. Peytevin, J., Aïoun, J., Chambille, I. Cell Tissue Res. (2000) [Pubmed]
 
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