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Chemical Compound Review

evans blue     tetrasodium(6E)-4-amino-6- [[4-[4-[(2Z)-2...

Synonyms: AC1NUWHB, CHEMBL1200712, AZOVAN SODIUM, DNC004420, CAS-314-13-6, ...
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  1. Mycoplasma pulmonis infections cause long-lasting potentiation of neurogenic inflammation in the respiratory tract of the rat. McDonald, D.M., Schoeb, T.R., Lindsey, J.R. J. Clin. Invest. (1991) [Pubmed]
  2. Animal models for muscular dystrophy show different patterns of sarcolemmal disruption. Straub, V., Rafael, J.A., Chamberlain, J.S., Campbell, K.P. J. Cell Biol. (1997) [Pubmed]
  3. Diagnostic ultrasound activation of contrast agent gas bodies induces capillary rupture in mice. Miller, D.L., Quddus, J. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  4. Activation of a 15-kDa endonuclease in hypoxia/reoxygenation injury without morphologic features of apoptosis. Ueda, N., Walker, P.D., Hsu, S.M., Shah, S.V. Proc. Natl. Acad. Sci. U.S.A. (1995) [Pubmed]
  5. Effects of acutely induced hypertension in cats on pial arteriolar caliber, local cerebral blood flow, and the blood-brain barrier. MacKenzie, E.T., Strandgaard, S., Graham, D.I., Jones, J.V., Harper, A.M., Farrar, J.K. Circ. Res. (1976) [Pubmed]
  6. Ultrastructural characteristics of the brain and blood-brain barrier in experimental seizures. Petito, C.K., Schaefer, J.A., Plum, F. Brain Res. (1977) [Pubmed]
  7. Alterations in blood-brain barrier function by morphine and methamphetamine. Sharma, H.S., Ali, S.F. Ann. N. Y. Acad. Sci. (2006) [Pubmed]
  8. A Potent Serotonin-Modulating Compound AP-267 Attenuates Morphine Withdrawal-Induced Blood-Brain Barrier Dysfunction in Rats. Sharma, H.S., Lundstedt, T., Boman, A., Lek, P., Seifert, E., Wiklund, L., Ali, S.F. Ann. N. Y. Acad. Sci. (2006) [Pubmed]
  9. Differential serum protein binding of benzidine- and benzidine-congener based dyes and their derivatives. Emmett, M., Cerniglia, C.E., Crowle, A.J. Arch. Toxicol. (1985) [Pubmed]
  10. Conservation of blood plasma fluids in hamadryas baboons after thermal dehydration. Zurovsky, Y., Shkolnik, A., Ovadia, M. Journal of applied physiology: respiratory, environmental and exercise physiology. (1984) [Pubmed]
  11. Fluorescent retrograde double labeling: axonal branching in the ascending raphe and nigral projections. van der Kooy, D., Kuypers, H.G. Science (1979) [Pubmed]
  12. Thrombin functions as an inflammatory mediator through activation of its receptor. Cirino, G., Cicala, C., Bucci, M.R., Sorrentino, L., Maraganore, J.M., Stone, S.R. J. Exp. Med. (1996) [Pubmed]
  13. Critical role of endothelial CXCR2 in LPS-induced neutrophil migration into the lung. Reutershan, J., Morris, M.A., Burcin, T.L., Smith, D.F., Chang, D., Saprito, M.S., Ley, K. J. Clin. Invest. (2006) [Pubmed]
  14. Increased vascular permeability in C1 inhibitor-deficient mice mediated by the bradykinin type 2 receptor. Han, E.D., MacFarlane, R.C., Mulligan, A.N., Scafidi, J., Davis, A.E. J. Clin. Invest. (2002) [Pubmed]
  15. Endonuclease-induced DNA damage and cell death in oxidant injury to renal tubular epithelial cells. Ueda, N., Shah, S.V. J. Clin. Invest. (1992) [Pubmed]
  16. Effect of aminophylline on postischemic edema and brain damage in cats. Seida, M., Wagner, H.G., Vass, K., Klatzo, I. Stroke (1988) [Pubmed]
  17. Pseudomonas elastase acts as a virulence factor in burned hosts by Hageman factor-dependent activation of the host kinin cascade. Holder, I.A., Neely, A.N. Infect. Immun. (1989) [Pubmed]
  18. Cellular resistance to Evans blue toxicity involves an up-regulation of a phosphate transporter implicated in vesicular glutamate storage. Israël, M., Tomasi, M., Bostel, S., Meunier, F.M. J. Neurochem. (2001) [Pubmed]
  19. Pharmacologic modulation of vascular permeability in ocular allergy in the rat. Calonge, M.C., Pastor, J.C., Herreras, J.M., González, J.L. Invest. Ophthalmol. Vis. Sci. (1990) [Pubmed]
  20. Mast cells mediate the severity of experimental cystitis in mice. Bjorling, D.E., Jerde, T.J., Zine, M.J., Busser, B.W., Saban, M.R., Saban, R. J. Urol. (1999) [Pubmed]
  21. Structural locus of transmucosal albumin efflux in canine ileum. A fluorescent study. Granger, D.N., Cook, B.H., Taylor, A.E. Gastroenterology (1976) [Pubmed]
  22. Deletion of murine SMN exon 7 directed to skeletal muscle leads to severe muscular dystrophy. Cifuentes-Diaz, C., Frugier, T., Tiziano, F.D., Lacène, E., Roblot, N., Joshi, V., Moreau, M.H., Melki, J. J. Cell Biol. (2001) [Pubmed]
  23. Cardiac atrophy after bed-rest deconditioning: a nonneural mechanism for orthostatic intolerance. Levine, B.D., Zuckerman, J.H., Pawelczyk, J.A. Circulation (1997) [Pubmed]
  24. Identification of a subunit-specific antagonist of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate/kainate receptor channels. Keller, B.U., Blaschke, M., Rivosecchi, R., Hollmann, M., Heinemann, S.F., Konnerth, A. Proc. Natl. Acad. Sci. U.S.A. (1993) [Pubmed]
  25. Rescue of hereditary form of dilated cardiomyopathy by rAAV-mediated somatic gene therapy: amelioration of morphological findings, sarcolemmal permeability, cardiac performances, and the prognosis of TO-2 hamsters. Kawada, T., Nakazawa, M., Nakauchi, S., Yamazaki, K., Shimamoto, R., Urabe, M., Nakata, J., Hemmi, C., Masui, F., Nakajima, T., Suzuki, J., Monahan, J., Sato, H., Masaki, T., Ozawa, K., Toyo-Oka, T. Proc. Natl. Acad. Sci. U.S.A. (2002) [Pubmed]
  26. Pathogenesis of ascites in mice with peritoneal carcinomatosis. Fastaia, J., Dumont, A.E. J. Natl. Cancer Inst. (1976) [Pubmed]
  27. Inhibition of intestinal motility and reversal of postlaparotomy ileus by selective alpha 2-adrenergic drugs in the rat. Tanila, H., Kauppila, T., Taira, T. Gastroenterology (1993) [Pubmed]
  28. Loss of calpain 3 proteolytic activity leads to muscular dystrophy and to apoptosis-associated IkappaBalpha/nuclear factor kappaB pathway perturbation in mice. Richard, I., Roudaut, C., Marchand, S., Baghdiguian, S., Herasse, M., Stockholm, D., Ono, Y., Suel, L., Bourg, N., Sorimachi, H., Lefranc, G., Fardeau, M., Sébille, A., Beckmann, J.S. J. Cell Biol. (2000) [Pubmed]
  29. Vascular smooth muscle cell growth kinetics in vivo in aged rats. Stemerman, M.B., Weinstein, R., Rowe, J.W., Maciag, T., Fuhro, R., Gardner, R. Proc. Natl. Acad. Sci. U.S.A. (1982) [Pubmed]
  30. Marked reduction in myocardial infarct size due to prolonged infusion of an antioxidant during reperfusion. Horwitz, L.D., Fennessey, P.V., Shikes, R.H., Kong, Y. Circulation (1994) [Pubmed]
  31. Neurogenically mediated leakage of plasma protein occurs from blood vessels in dura mater but not brain. Markowitz, S., Saito, K., Moskowitz, M.A. J. Neurosci. (1987) [Pubmed]
  32. Vascular differentiation and glucose transporter expression in rat gliomas: effects of steroids. Guerin, C., Wolff, J.E., Laterra, J., Drewes, L.R., Brem, H., Goldstein, G.W. Ann. Neurol. (1992) [Pubmed]
  33. The chemotactic response of tumor cells. A model for cancer metastasis. Lam, W.C., Delikatny, E.J., Orr, F.W., Wass, J., Varani, J., Ward, P.A. Am. J. Pathol. (1981) [Pubmed]
  34. Effects of chronic oral consumption of nicotine on the rabbit aortic endothelium. Booyse, F.M., Osikowicz, G., Quarfoot, A.J. Am. J. Pathol. (1981) [Pubmed]
  35. Gamma-sarcoglycan deficiency leads to muscle membrane defects and apoptosis independent of dystrophin. Hack, A.A., Ly, C.T., Jiang, F., Clendenin, C.J., Sigrist, K.S., Wollmann, R.L., McNally, E.M. J. Cell Biol. (1998) [Pubmed]
  36. Corticotropin-releasing hormone induces skin vascular permeability through a neurotensin-dependent process. Donelan, J., Boucher, W., Papadopoulou, N., Lytinas, M., Papaliodis, D., Dobner, P., Theoharides, T.C. Proc. Natl. Acad. Sci. U.S.A. (2006) [Pubmed]
  37. Adenovirus-mediated utrophin gene transfer mitigates the dystrophic phenotype of mdx mouse muscles. Gilbert, R., Nalbantoglu, J., Petrof, B.J., Ebihara, S., Guibinga, G.H., Tinsley, J.M., Kamen, A., Massie, B., Davies, K.E., Karpati, G. Hum. Gene Ther. (1999) [Pubmed]
  38. Activation of the insulin-like growth factor 1 signaling pathway by the antiapoptotic agents aurintricarboxylic acid and evans blue. Beery, R., Haimsohn, M., Wertheim, N., Hemi, R., Nir, U., Karasik, A., Kanety, H., Geier, A. Endocrinology (2001) [Pubmed]
  39. Delayed mortality and attenuated thrombocytopenia associated with severe malaria in urokinase- and urokinase receptor-deficient mice. Piguet, P.F., Da Laperrousaz, C., Vesin, C., Tacchini-Cottier, F., Senaldi, G., Grau, G.E. Infect. Immun. (2000) [Pubmed]
  40. Tumor necrosis factor/cachectin-induced intravascular fibrin formation in meth A fibrosarcomas. Nawroth, P., Handley, D., Matsueda, G., De Waal, R., Gerlach, H., Blohm, D., Stern, D. J. Exp. Med. (1988) [Pubmed]
  41. Myocardial protective effects of adenosine. Infarct size reduction with pretreatment and continued receptor stimulation during ischemia. Toombs, C.F., McGee, S., Johnston, W.E., Vinten-Johansen, J. Circulation (1992) [Pubmed]
  42. Impact of Rantes and MCP-1 chemokines on in vivo basophilic cell recruitment in rat skin injection model and their role in modifying the protein and mRNA levels for histidine decarboxylase. Conti, P., Pang, X., Boucher, W., Letourneau, R., Reale, M., Barbacane, R.C., Thibault, J., Theoharides, T.C. Blood (1997) [Pubmed]
  43. Endothelial apoptosis initiates acute blood-brain barrier disruption after ionizing radiation. Li, Y.Q., Chen, P., Haimovitz-Friedman, A., Reilly, R.M., Wong, C.S. Cancer Res. (2003) [Pubmed]
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