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Chemical Compound Review

AC1L998U     (4S,5R,6R)-5-acetamido-4- hydroxy-6-(1,2,3...

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Biological context of C04580


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  1. Crystal structure of a bacterial sialidase (from Salmonella typhimurium LT2) shows the same fold as an influenza virus neuraminidase. Crennell, S.J., Garman, E.F., Laver, W.G., Vimr, E.R., Taylor, G.L. Proc. Natl. Acad. Sci. U.S.A. (1993) [Pubmed]
  2. A fusing mumps virus variant selected from a nonfusing parent with the neuraminidase inhibitor 2-deoxy-2,3-dehydro-N-acetylneuraminic acid. Waxham, M.N., Wolinsky, J.S. Virology (1986) [Pubmed]
  3. Isolation and identification of 2-deoxy-2,3-dehydro-N-acetylneuraminic acid from the urine of a patient with sialuria. Kamerling, J.P., Vliegenthart, J.F. Eur. J. Biochem. (1975) [Pubmed]
  4. Effects of GM1 and 2-deoxy-2,3-dehydro-N-acetylneuraminic acid (NeuAc2en) on neuroblastoma (Neuro 2a) and human glioma cells (U1242 MG). el Sayed, H., Agudelo, J.D., Pearl, D.K., Yates, A.J. J. Neurooncol. (1991) [Pubmed]
  5. Crystal structure of the human cytosolic sialidase Neu2. Evidence for the dynamic nature of substrate recognition. Chavas, L.M., Tringali, C., Fusi, P., Venerando, B., Tettamanti, G., Kato, R., Monti, E., Wakatsuki, S. J. Biol. Chem. (2005) [Pubmed]
  6. Galectin-1 is a major receptor for ganglioside GM1, a product of the growth-controlling activity of a cell surface ganglioside sialidase, on human neuroblastoma cells in culture. Kopitz, J., von Reitzenstein, C., Burchert, M., Cantz, M., Gabius, H.J. J. Biol. Chem. (1998) [Pubmed]
  7. Growth control of human foreskin fibroblasts and inhibition of extracellular sialidase activity by 2-deoxy-2,3-dehydro-N-acetylneuraminic acid. Usuki, S., Hoops, P., Sweeley, C.C. J. Biol. Chem. (1988) [Pubmed]
  8. Role of the hemagglutinin-neuraminidase protein in the mechanism of paramyxovirus-cell membrane fusion. Takimoto, T., Taylor, G.L., Connaris, H.C., Crennell, S.J., Portner, A. J. Virol. (2002) [Pubmed]
  9. Novel alpha- and beta-amino acid inhibitors of influenza virus neuraminidase. Kati, W.M., Montgomery, D., Maring, C., Stoll, V.S., Giranda, V., Chen, X., Laver, W.G., Kohlbrenner, W., Norbeck, D.W. Antimicrob. Agents Chemother. (2001) [Pubmed]
  10. Neuraminidase-dependent hamagglutination of human erythrocytes by human strains of Actinomyces viscosus and Actinomyces naeslundii. Costello, A.H., Cisar, J.O., Kolenbrander, P.E., Gabriel, O. Infect. Immun. (1979) [Pubmed]
  11. Two nucleophilic mutants of the Micromonospora viridifaciens sialidase operate with retention of configuration by two different mechanisms. Watson, J.N., Newstead, S., Narine, A.A., Taylor, G., Bennet, A.J. Chembiochem (2005) [Pubmed]
  12. Differential functional relevance of a plasma membrane ganglioside sialidase in cholinergic and adrenergic neuroblastoma cell lines. von Reitzenstein, C., Kopitz, J., Schuhmann, V., Cantz, M. Eur. J. Biochem. (2001) [Pubmed]
  13. Dependence of neurotrophic factor activation of Trk tyrosine kinase receptors on cellular sialidase. Woronowicz, A., Amith, S.R., De Vusser, K., Laroy, W., Contreras, R., Basta, S., Szewczuk, M.R. Glycobiology (2007) [Pubmed]
  14. Regulation of B cell:T cell interactions: potential involvement of an endogenous B cell sialidase. Guthridge, J.M., Kaplan, A.M., Cohen, D.A. Immunol. Invest. (1994) [Pubmed]
  15. Effects of cell surface ganglioside sialidase inhibition on growth control and differentiation of human neuroblastoma cells. Kopitz, J., Mühl, C., Ehemann, V., Lehmann, C., Cantz, M. Eur. J. Cell Biol. (1997) [Pubmed]
  16. Structural analysis of a designed inhibitor complexed with the hemagglutinin-neuraminidase of Newcastle disease virus. Ryan, C., Zaitsev, V., Tindal, D.J., Dyason, J.C., Thomson, R.J., Alymova, I., Portner, A., Itzstein, M., Taylor, G. Glycoconj. J. (2006) [Pubmed]
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