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MeSH Review

Lymphocyte Culture Test, Mixed

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Disease relevance of Lymphocyte Culture Test, Mixed


High impact information on Lymphocyte Culture Test, Mixed

  • The demonstration that stimulation in the mixed lymphocyte reaction (MLR) mapped to the same region quickly led to attempts to produce antisera in congenic H2 recombinant strain combinations [7].
  • Incorporation of murine MHC antigens into liposomes and their effect in the secondary mixed lymphocyte reaction [8].
  • Cyclophilin specifically binds a series of cyclosporin analogs in proportion to their activity in a mixed lymphocyte reaction [9].
  • Antiserums to C4 inhibited the mixed lymphocyte reaction and the mitogenic response to phytohemagglutinin, suggesting a role for membrane-associated C4 in the afferent phase of immune recognition phenomena [10].
  • We utilize these mice to identify previously undefined cellular targets of IFN gamma action in the development of a murine antimicrobial response and the mixed lymphocyte reaction [11].

Chemical compound and disease context of Lymphocyte Culture Test, Mixed


Biological context of Lymphocyte Culture Test, Mixed


Anatomical context of Lymphocyte Culture Test, Mixed


Associations of Lymphocyte Culture Test, Mixed with chemical compounds


Gene context of Lymphocyte Culture Test, Mixed


Analytical, diagnostic and therapeutic context of Lymphocyte Culture Test, Mixed


  1. Selective immunoglobulin A deficiency associated with primary biliary cirrhosis in a family with liver disease. James, S.P., Jones, E.A., Schafer, D.F., Hoofnagle, J.H., Varma, R.R., Strober, W. Gastroenterology (1986) [Pubmed]
  2. HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation. Granelli-Piperno, A., Golebiowska, A., Trumpfheller, C., Siegal, F.P., Steinman, R.M. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  3. Influence of asparagine-linked oligosaccharides on tumor cell recognition in the mixed lymphocyte reaction. Powell, L.D., Bause, E., Legler, G., Molyneux, R.J., Hart, G.W. J. Immunol. (1985) [Pubmed]
  4. IL-10 prevents the differentiation of monocytes to dendritic cells but promotes their maturation to macrophages. Allavena, P., Piemonti, L., Longoni, D., Bernasconi, S., Stoppacciaro, A., Ruco, L., Mantovani, A. Eur. J. Immunol. (1998) [Pubmed]
  5. Effect of estrogen on the mixed lymphocyte reaction in normal individuals and prostatic cancer patients. Herr, H.W. Prostate (1982) [Pubmed]
  6. Loci controlling lymphocyte production of interferon gamma after alloantigen stimulation in vitro and their co-localization with genes controlling lymphocyte infiltration of tumors and tumor susceptibility. Lipoldová, M., Havelková, H., Badalová, J., Vojtíšková, J., Quan, L., Krulová, M., Sohrabi, Y., Stassen, A.P., Demant, P. Cancer. Immunol. Immunother. (2009) [Pubmed]
  7. Discovering the role of the major histocompatibility complex in the immune response. McDevitt, H.O. Annu. Rev. Immunol. (2000) [Pubmed]
  8. Incorporation of murine MHC antigens into liposomes and their effect in the secondary mixed lymphocyte reaction. Curman, B., Ostberg, L., Peterson, P.A. Nature (1978) [Pubmed]
  9. Cyclophilin: a specific cytosolic binding protein for cyclosporin A. Handschumacher, R.E., Harding, M.W., Rice, J., Drugge, R.J., Speicher, D.W. Science (1984) [Pubmed]
  10. Expression of C4 on human lymphoid cells and possible involvement in immune recognition phenomena. Ferrone, S., Pellegrino, M.A., Cooper, N.R. Science (1976) [Pubmed]
  11. Tissue-specific targeting of cytokine unresponsiveness in transgenic mice. Dighe, A.S., Campbell, D., Hsieh, C.S., Clarke, S., Greaves, D.R., Gordon, S., Murphy, K.M., Schreiber, R.D. Immunity (1995) [Pubmed]
  12. Azathioprine suppresses the mixed lymphocyte reaction of patients with Lesch-Nyhan syndrome. Szawlowski, P.W., Al-Safi, S.A., Dooley, T., Maddocks, J.L. British journal of clinical pharmacology. (1985) [Pubmed]
  13. Effects of a novel purine nucleoside phosphorylase inhibitor, BCX-34, on activation and proliferation of normal human lymphoid cells. Conry, R.M., Bantia, S., Turner, H.S., Barlow, D.L., Allen, K.O., LoBuglio, A.F., Montgomery, J.A., Walsh, G.M. Immunopharmacology (1998) [Pubmed]
  14. Differential effect of mixed D1/D2 and selective D2 dopaminergic antagonists on mouse T and B lymphocyte proliferation and interleukin production in vitro. Boukhris, W., Kouassi, E., Revillard, J.P. Immunopharmacology and immunotoxicology. (1988) [Pubmed]
  15. Characterization of the phosphodiesterase (PDE) pattern of in vitro-generated human dendritic cells (DC) and the influence of PDE inhibitors on DC function. Gantner, F., Schudt, C., Wendel, A., Hatzelmann, A. Pulmonary pharmacology & therapeutics. (1999) [Pubmed]
  16. Effect of acute propanil exposure on the immune response of C57Bl/6 mice. Barnett, J.B., Gandy, J. Fundamental and applied toxicology : official journal of the Society of Toxicology. (1989) [Pubmed]
  17. B6.C-H-2bm12. A new H-2 mutation in the I region in the mouse. McKenzie, I.F., Morgan, G.M., Sandrin, M.S., Michaelides, M.M., Melvold, R.W., Kohn, H.I. J. Exp. Med. (1979) [Pubmed]
  18. Stimulation of autologous proliferative and cytotoxic T-cell responses by leukemic dendritic cells derived from blast cells in acute myeloid leukemia. Harrison, B.D., Adams, J.A., Briggs, M., Brereton, M.L., Yin, J.A. Blood (2001) [Pubmed]
  19. Ikappa B kinase 2 but not NF-kappa B-inducing kinase is essential for effective DC antigen presentation in the allogeneic mixed lymphocyte reaction. Andreakos, E., Smith, C., Monaco, C., Brennan, F.M., Foxwell, B.M., Feldmann, M. Blood (2003) [Pubmed]
  20. Mechanisms responsible for granzyme B-independent cytotoxicity. Shresta, S., Russell, J.H., Ley, T.J. Blood (1997) [Pubmed]
  21. Allogeneic mixed lymphocyte reactions during a second round of ontogeny: normal accessory cells did not restore defective interleukin-2 (IL-2) synthesis in T cells but induced responsiveness to exogeneous IL-2. Cayeux, S., Meuer, S., Pezzutto, A., Körbling, M., Haas, R., Schulz, R., Dörken, B. Blood (1989) [Pubmed]
  22. Spontaneous internalization of Class I major histocompatibility complex molecules in T lymphoid cells. Tse, D.B., Pernis, B. J. Exp. Med. (1984) [Pubmed]
  23. Interactions between T helper cells and dendritic cells during the rat mixed lymphocyte reaction. Green, J., Jotte, R. J. Exp. Med. (1985) [Pubmed]
  24. Suppressor T cells activated in a primary in vitro response to non-major histocompatibility alloantigens. Macphail, S., Stutman, O. J. Exp. Med. (1982) [Pubmed]
  25. Helper cells in the autologous mixed lymphocyte reaction. III. Production of helper factor(s) distinct from interleukin 2. Wolos, J.A., Smith, J.B. J. Exp. Med. (1982) [Pubmed]
  26. Human placental cytotrophoblasts produce the immunosuppressive cytokine interleukin 10. Roth, I., Corry, D.B., Locksley, R.M., Abrams, J.S., Litton, M.J., Fisher, S.J. J. Exp. Med. (1996) [Pubmed]
  27. Intrathymic clonal deletion of V beta 6+ T cells in cyclophosphamide-induced tolerance to H-2-compatible, Mls-disparate antigens. Eto, M., Mayumi, H., Tomita, Y., Yoshikai, Y., Nomoto, K. J. Exp. Med. (1990) [Pubmed]
  28. Antigen stimulation of prostaglandin synthesis and control of immune responses. Webb, D.R., Osheroff, P.L. Proc. Natl. Acad. Sci. U.S.A. (1976) [Pubmed]
  29. Differential deactivation of human dendritic cells by endotoxin desensitization: role of tumor necrosis factor-alpha and prostaglandin E2. Rieser, C., Papesh, C., Herold, M., Böck, G., Ramoner, R., Klocker, H., Bartsch, G., Thurnher, M. Blood (1998) [Pubmed]
  30. Thymocyte cyclic AMP and cyclic GMP response to treatment with metabolites issued from the lipoxygenase pathway. Mexmain, S., Cook, J., Aldigier, J.C., Gualde, N., Rigaud, M. J. Immunol. (1985) [Pubmed]
  31. The role of toll-like receptors (TLRs) in bacteria-induced maturation of murine dendritic cells (DCS). Peptidoglycan and lipoteichoic acid are inducers of DC maturation and require TLR2. Michelsen, K.S., Aicher, A., Mohaupt, M., Hartung, T., Dimmeler, S., Kirschning, C.J., Schumann, R.R. J. Biol. Chem. (2001) [Pubmed]
  32. Neutralization of tumor necrosis factor activity shortly after the onset of dendritic cell hematopoiesis reveals a novel mechanism for the selective expansion of the CD14-dependent dendritic cell pathway. Santiago-Schwarz, F., McCarthy, M., Tucci, J., Carsons, S.E. Blood (1998) [Pubmed]
  33. Characterization of the production of monocyte chemoattractant protein-1 and IL-8 in an allogeneic immune response. Christensen, P.J., Rolfe, M.W., Standiford, T.J., Burdick, M.D., Toews, G.B., Strieter, R.M. J. Immunol. (1993) [Pubmed]
  34. FcgammaR cross-linking mediates NF-kappaB activation, reduced antigen presentation capacity, and decreased IL-12 production in monocytes without modulation of myeloid dendritic cell development. Drechsler, Y., Chavan, S., Catalano, D., Mandrekar, P., Szabo, G. J. Leukoc. Biol. (2002) [Pubmed]
  35. Interleukin-10 differentially regulates B7-1 (CD80) and B7-2 (CD86) expression on human peripheral blood dendritic cells. Buelens, C., Willems, F., Delvaux, A., Piérard, G., Delville, J.P., Velu, T., Goldman, M. Eur. J. Immunol. (1995) [Pubmed]
  36. Effect of beta2-adrenergic receptor agonists on intercellular adhesion molecule (ICAM)-1, B7, and CD40 expression in mixed lymphocyte reaction. Tamura, R., Takahashi, H.K., Iwagaki, H., Yagi, T., Mori, S., Yoshino, T., Nishibori, M., Tanaka, N. Transplantation (2004) [Pubmed]
  37. A novel alloreactivity-controlling locus, Alan1, mapped to mouse chromosome 17. Holán, V., Havelková, H., Krulová, M., Demant, P., Lipoldová, M. Immunogenetics. (2000) [Pubmed]
  38. A new type of genetic regulation of allogeneic response. A novel locus on mouse chromosome 4, Alan2 controls MLC reactivity to three different alloantigens: C57BL/10, BALB/c and CBA. Havelková, H., Badalová, J., Demant, P., Lipoldová, M. Genes. Immun. (2000) [Pubmed]
  39. Immunization of stage IV melanoma patients with Melan-A/MART-1 and gp100 peptides plus IFN-alpha results in the activation of specific CD8(+) T cells and monocyte/dendritic cell precursors. Di Pucchio, T., Pilla, L., Capone, I., Ferrantini, M., Montefiore, E., Urbani, F., Patuzzo, R., Pennacchioli, E., Santinami, M., Cova, A., Sovena, G., Arienti, F., Lombardo, C., Lombardi, A., Caporaso, P., D'Atri, S., Marchetti, P., Bonmassar, E., Parmiani, G., Belardelli, F., Rivoltini, L. Cancer Res. (2006) [Pubmed]
  40. Ex vivo expanded dendritic cells home to T-cell zones of lymphoid organs and survive in vivo after allogeneic bone marrow transplantation. Schimmelpfennig, C.H., Schulz, S., Arber, C., Baker, J., Tarner, I., McBride, J., Contag, C.H., Negrin, R.S. Am. J. Pathol. (2005) [Pubmed]
  41. Humoral immunity in kidney transplant recipients. Ferrone, S., Halasz, N.A., Collins, G., Pellegrino, M.A. Transplantation (1977) [Pubmed]
  42. Lectin separation of nonlymphoid suppressor cells induced by total lymphoid irradiation. Morecki, S., Weigensberg, M., Slavin, S. Eur. J. Immunol. (1985) [Pubmed]
  43. Anti-CD154 or CTLA4Ig obviates the need for thymic irradiation in a non-myeloablative conditioning regimen for the induction of mixed hematopoietic chimerism and tolerance. Wekerle, T., Sayegh, M.H., Ito, H., Hill, J., Chandraker, A., Pearson, D.A., Swenson, K.G., Zhao, G., Sykes, M. Transplantation (1999) [Pubmed]
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