Gene Review:
NEU2 - sialidase 2 (cytosolic sialidase)
Homo sapiens
Synonyms:
Cytosolic sialidase, N-acetyl-alpha-neuraminidase 2, SIAL2, Sialidase-2
- Properties of recombinant human cytosolic sialidase HsNEU2. The enzyme hydrolyzes monomerically dispersed GM1 ganglioside molecules. Tringali, C., Papini, N., Fusi, P., Croci, G., Borsani, G., Preti, A., Tortora, P., Tettamanti, G., Venerando, B., Monti, E. J. Biol. Chem. (2004)
- Insulin-like growth factor 1 signaling regulates cytosolic sialidase Neu2 expression during myoblast differentiation and hypertrophy. Fanzani, A., Colombo, F., Giuliani, R., Preti, A., Marchesini, S. FEBS J. (2006)
- Crystal structure of the human cytosolic sialidase Neu2. Evidence for the dynamic nature of substrate recognition. Chavas, L.M., Tringali, C., Fusi, P., Venerando, B., Tettamanti, G., Kato, R., Monti, E., Wakatsuki, S. J. Biol. Chem. (2005)
- Molecular cloning and expression of cDNA encoding rat skeletal muscle cytosolic sialidase. Miyagi, T., Konno, K., Emori, Y., Kawasaki, H., Suzuki, K., Yasui, A., Tsuik, S. J. Biol. Chem. (1993)
- Dependence of neurotrophic factor activation of Trk tyrosine kinase receptors on cellular sialidase. Woronowicz, A., Amith, S.R., De Vusser, K., Laroy, W., Contreras, R., Basta, S., Szewczuk, M.R. Glycobiology (2007)
- Molecular cloning and characterization of NEU4, the fourth member of the human sialidase gene family. Monti, E., Bassi, M.T., Bresciani, R., Civini, S., Croci, G.L., Papini, N., Riboni, M., Zanchetti, G., Ballabio, A., Preti, A., Tettamanti, G., Venerando, B., Borsani, G. Genomics (2004)
- Homology modeling of human sialidase enzymes NEU1, NEU3 and NEU4 based on the crystal structure of NEU2: Hints for the design of selective NEU3 inhibitors. Magesh, S., Suzuki, T., Miyagi, T., Ishida, H., Kiso, M. J. Mol. Graph. Model. (2006)
- Expression of a novel human sialidase encoded by the NEU2 gene. Monti, E., Preti, A., Nesti, C., Ballabio, A., Borsani, G. Glycobiology (1999)
- Cloning and characterization of NEU2, a human gene homologous to rodent soluble sialidases. Monti, E., Preti, A., Rossi, E., Ballabio, A., Borsani, G. Genomics (1999)
- Differential expression of endogenous sialidases of human monocytes during cellular differentiation into macrophages. Stamatos, N.M., Liang, F., Nan, X., Landry, K., Cross, A.S., Wang, L.X., Pshezhetsky, A.V. FEBS J. (2005)