Chemical Compound Review:
Arctigenen (3R,4S)-4-[(3,4- dimethoxyphenyl)methyl]-3...
Synonyms:
Arctigenin, Tocris-1777, CHEMBL435734, SureCN381820, A1854_SIGMA, ...
- Identification of arctigenin as an antitumor agent having the ability to eliminate the tolerance of cancer cells to nutrient starvation. Awale, S., Lu, J., Kalauni, S.K., Kurashima, Y., Tezuka, Y., Kadota, S., Esumi, H. Cancer Res. (2006)
- Arctigenin protects cultured cortical neurons from glutamate-induced neurodegeneration by binding to kainate receptor. Jang, Y.P., Kim, S.R., Choi, Y.H., Kim, J., Kim, S.G., Markelonis, G.J., Oh, T.H., Kim, Y.C. J. Neurosci. Res. (2002)
- Arctigenin from Fructus Arctii is a novel suppressor of heat shock response in mammalian cells. Ishihara, K., Yamagishi, N., Saito, Y., Takasaki, M., Konoshima, T., Hatayama, T. Cell Stress Chaperones (2006)
- Natural flavonoids and lignans are potent cytostatic agents against human leukemic HL-60 cells. Hirano, T., Gotoh, M., Oka, K. Life Sci. (1994)
- Lignans from Saussurea conica and their NO production suppressing activity. Fan, C.Q., Zhu, X.Z., Zhan, Z.J., Ji, X.Q., Li, H., Yue, J.M. Planta Med. (2006)
- Naturally occurring lignans efficiently induce apoptosis in colorectal tumor cells. Hausott, B., Greger, H., Marian, B. J. Cancer Res. Clin. Oncol. (2003)
- Structural transformation of lignan compounds in rat gastrointestinal tract. Nose, M., Fujimoto, T., Takeda, T., Nishibe, S., Ogihara, Y. Planta Med. (1992)
- Anti-tumor-promoting activity of lignans from the aerial part of Saussurea medusa. Takasaki, M., Konoshima, T., Komatsu, K., Tokuda, H., Nishino, H. Cancer Lett. (2000)
- Studies on differentiation inducers. VI. Lignan derivatives from Arctium fructus. (2). Umehara, K., Nakamura, M., Miyase, T., Kuroyanagi, M., Ueno, A. Chem. Pharm. Bull. (1996)
- Potent inhibition of lipopolysaccharide-inducible nitric oxide synthase expression by dibenzylbutyrolactone lignans through inhibition of I-kappaBalpha phosphorylation and of p65 nuclear translocation in macrophages. Cho, M.K., Park, J.W., Jang, Y.P., Kim, Y.C., Kim, S.G. Int. Immunopharmacol. (2002)
- Arctigenin, a phenylpropanoid dibenzylbutyrolactone lignan, inhibits MAP kinases and AP-1 activation via potent MKK inhibition: the role in TNF-alpha inhibition. Cho, M.K., Jang, Y.P., Kim, Y.C., Kim, S.G. Int. Immunopharmacol. (2004)
- Immunomodulatory effect of arctigenin, a lignan compound, on tumour necrosis factor-alpha and nitric oxide production, and lymphocyte proliferation. Cho, J.Y., Kim, A.R., Yoo, E.S., Baik, K.U., Park, M.H. J. Pharm. Pharmacol. (1999)
- Hepatoprotective dibenzylbutyrolactone lignans of Torreya nucifera against CCl4-induced toxicity in primary cultured rat hepatocytes. Kim, S.H., Jang, Y.P., Sung, S.H., Kim, C.J., Kim, J.W., Kim, Y.C. Biol. Pharm. Bull. (2003)