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Chemical Compound Review

Butylphen     4-tert-butylphenol

Synonyms: PTBP, CHEMBL16217, SureCN19157, NSC-3697, B99901_ALDRICH, ...
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Disease relevance of p-t-Butyl phenol


High impact information on p-t-Butyl phenol


Biological context of p-t-Butyl phenol


Anatomical context of p-t-Butyl phenol


Associations of p-t-Butyl phenol with other chemical compounds


Gene context of p-t-Butyl phenol

  • 2,6-Dimethylol p-tert-butylphenol, p-tert-butylcate chol, 2-methylol p-tert-butylphenol, p-tert-butylphenol, 4-tert-butyl-2-(5-tert-butyl-2-hydroxy-3-hydroxymethyl-benzyloxymethyl)-6-hydroxymethyl-phenol and 4-tert-butyl-2-(5-tert-butyl-2-hydroxy-benzyloxymethyl)-phenol were used as potential cross-reacting substances [17].


  1. Contact allergy to the monomers in p-tert-butylphenol-formaldehyde resin. Zimerson, E., Bruze, M. Contact Derm. (2002) [Pubmed]
  2. Studies on antioxidants: their carcinogenic and modifying effects on chemical carcinogenesis. Ito, N., Hirose, M., Fukushima, S., Tsuda, H., Shirai, T., Tatematsu, M. Food Chem. Toxicol. (1986) [Pubmed]
  3. Occupational vitiligo induced by p-tert-butylphenol, a systemic disease? James, O., Mayes, R.W., Stevenson, C.J. Lancet (1977) [Pubmed]
  4. A Role for Tyrosinase-Related Protein 1 in 4-tert-Butylphenol-Induced Toxicity in Melanocytes: Implications for Vitiligo. Manga, P., Sheyn, D., Yang, F., Sarangarajan, R., Boissy, R.E. Am. J. Pathol. (2006) [Pubmed]
  5. Activation of dual apoptotic pathways in human melanocytes and protection by survivin. Liu, T., Biddle, D., Hanks, A.N., Brouha, B., Yan, H., Lee, R.M., Leachman, S.A., Grossman, D. J. Invest. Dermatol. (2006) [Pubmed]
  6. Apoptosis regulators and responses in human melanocytic and keratinocytic cells. Bowen, A.R., Hanks, A.N., Allen, S.M., Alexander, A., Diedrich, M.J., Grossman, D. J. Invest. Dermatol. (2003) [Pubmed]
  7. Comparison of the effects of 13 phenolic compounds in induction of proliferative lesions of the forestomach and increase in the labelling indices of the glandular stomach and urinary bladder epithelium of Syrian golden hamsters. Hirose, M., Inoue, T., Asamoto, M., Tagawa, Y., Ito, N. Carcinogenesis (1986) [Pubmed]
  8. Relevance of chemical structure and cytotoxicity to the induction of chromosome aberrations based on the testing results of 98 high production volume industrial chemicals. Kusakabe, H., Yamakage, K., Wakuri, S., Sasaki, K., Nakagawa, Y., Watanabe, M., Hayashi, M., Sofuni, T., Ono, H., Tanaka, N. Mutat. Res. (2002) [Pubmed]
  9. Simultaneous determination of alkylphenols and bisphenol A in river water by stir bar sorptive extraction with in situ acetylation and thermal desorption-gas chromatography-mass spectrometry. Nakamura, S., Daishima, S. Journal of chromatography. A. (2004) [Pubmed]
  10. Kinetics study of the oxidation of 4-tert-butylphenol by tyrosinase. Ros, J.R., Rodríguez-López, J.N., Varón, R., García-Cánovas, F. Eur. J. Biochem. (1994) [Pubmed]
  11. European Standard Series patch test results from a contact dermatitis clinic in Israel during the 7-year period from 1998 to 2004. Lazarov, A. Contact Derm. (2006) [Pubmed]
  12. In vitro effects of diethylstilbestrol, genistein, 4-tert-butylphenol, and 4-tert-octylphenol on steroidogenic activity of isolated immature rat ovarian follicles. Myllymäki, S., Haavisto, T., Vainio, M., Toppari, J., Paranko, J. Toxicol. Appl. Pharmacol. (2005) [Pubmed]
  13. Influence of para substituent of phenol on phospholipid dependence of uridine diphosphate-glucuronyltransferase. Nanbo, T. J. Pharmacobio-dyn. (1992) [Pubmed]
  14. Simultaneous p-tert-butylphenol-formaldehyde resin and p-tert-butylcatechol contact allergies in man and sensitizing capacities of p-tert-butylphenol and p-tert-butylcatechol in guinea pigs. Zimerson, E., Bruze, M., Goossens, A. J. Occup. Environ. Med. (1999) [Pubmed]
  15. Effect of 3-hydroxyanthranilic acid on mushroom tyrosinase activity. Rescigno, A., Sanjust, E., Soddu, G., Rinaldi, A.C., Sollai, F., Curreli, N., Rinaldi, A. Biochim. Biophys. Acta (1998) [Pubmed]
  16. Hydrogen peroxide-dependent 4-t-butylphenol hydroxylation by tyrosinase--a new catalytic activity. Jiménez, M., García-Carmona, F. Biochim. Biophys. Acta (1996) [Pubmed]
  17. Sensitizing capacity of two monomeric aldehyde components in p-tert-butylphenol-formaldehyde resin. Zimerson, E., Bruze, M. Acta Derm. Venereol. (2002) [Pubmed]
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