Chemical Compound Review:
Dibunol 4-methyl-2,6-ditert-butyl- phenol
Synonyms:
Impruvol, Ionol, BHT, Butylhydroxytoluene, Butylated hydroxytoluene, ...
- Toxicity of butylated hydroxytoluene. Shlian, D.M., Goldstone, J. N. Engl. J. Med. (1986)
- Butylated hydroxytoluene protects chickens exposed to Newcastle disease virus. Brugh, M. Science (1977)
- Effects of butylated hydroxyanisole, butylated hydroxytoluene, and NaCl on gastric carcinogenesis initiated with N-methyl-N'-nitro-N-nitrosoguanidine in F344 rats. Shirai, T., Fukushima, S., Ohshima, M., Masuda, A., Ito, N. J. Natl. Cancer Inst. (1984)
- Histologic and autoradiographic studies on the forestomach of hamsters treated with 2-tert-butylated hydroxyanisole, 3-tert-butylated hydroxyanisole, crude butylated hydroxyanisole, or butylated hydroxytoluene. Hirose, M., Masuda, A., Kurata, Y., Ikawa, E., Mera, Y., Ito, N. J. Natl. Cancer Inst. (1986)
- Pharmacologic and genetic studies on the modulatory effects of butylated hydroxytoluene on mouse lung adenoma formation. Malkinson, A.M., Beer, D.S. J. Natl. Cancer Inst. (1984)
- Phenolic antioxidants: Health Protection Branch studies on butylated hydroxyanisole. Iverson, F. Cancer Lett. (1995)
- Myeloperoxidase-generated reactive nitrogen species convert LDL into an atherogenic form in vitro. Podrez, E.A., Schmitt, D., Hoff, H.F., Hazen, S.L. J. Clin. Invest. (1999)
- The antioxidant butylated hydroxytoluene prevents early cholesterol-induced microcirculatory changes in rabbits. Xiu, R.J., Freyschuss, A., Ying, X., Berglund, L., Henriksson, P., Björkhem, I. J. Clin. Invest. (1994)
- Antioxidant treatment inhibits the development of intimal thickening after balloon injury of the aorta in hypercholesterolemic rabbits. Freyschuss, A., Stiko-Rahm, A., Swedenborg, J., Henriksson, P., Björkhem, I., Berglund, L., Nilsson, J. J. Clin. Invest. (1993)
- Combination chemoprevention of rat mammary carcinogenesis by indomethacin and butylated hydroxytoluene. McCormick, D.L., Wilson, A.M. Cancer Res. (1986)
- Anti-oxidant treatment prevents the development of peripheral nerve dysfunction in streptozotocin-diabetic rats. Cameron, N.E., Cotter, M.A., Maxfield, E.K. Diabetologia (1993)
- Oxygen radicals in lung pathology. Doelman, C.J., Bast, A. Free Radic. Biol. Med. (1990)
- Effects of several agents on UVB- and UVA plus systemic fluoroquinolone-induced erythema of guinea pig skin evaluated by reflectance colorimetry. Akter, U., Niwa, M., Nose, T., Kaida, T., Matsuno, H., Kozawa, O., Uematsu, T. Free Radic. Biol. Med. (1998)
- Enhancement of urethan tumorigenesis in mouse lung by butylated hydroxytoluene. Witschi, H., Williamson, D., Lock, S. J. Natl. Cancer Inst. (1977)
- Enhancement of lung tumor formation in mice by dietary butylated hydroxytoluene: dose-time relationships and cell kinetics. Witschi, H.R., Morse, C.C. J. Natl. Cancer Inst. (1983)
- Pertussis toxin-sensitive G protein mediates coronary microvascular control during autoregulation and ischemia in canine heart. Komaru, T., Wang, Y., Akai, K., Sato, K., Sekiguchi, N., Sugimura, A., Kumagai, T., Kanatsuka, H., Shirato, K. Circ. Res. (1994)
- Reduced glutathione depletion causes necrosis and sensitization to tumor necrosis factor-alpha-induced apoptosis in cultured mouse hepatocytes. Nagai, H., Matsumaru, K., Feng, G., Kaplowitz, N. Hepatology (2002)
- Modulation of azaserine-induced pancreatic foci by phenolic antioxidants in rats. Roebuck, B.D., MacMillan, D.L., Bush, D.M., Kensler, T.W. J. Natl. Cancer Inst. (1984)
- Clostridium difficile toxin A causes early damage to mitochondria in cultured cells. He, D., Hagen, S.J., Pothoulakis, C., Chen, M., Medina, N.D., Warny, M., LaMont, J.T. Gastroenterology (2000)
- Role of alpha 2-adrenoceptors in normal and atherosclerotic human coronary circulation. Indolfi, C., Piscione, F., Villari, B., Russolillo, E., Rendina, V., Golino, P., Condorelli, M., Chiariello, M. Circulation (1992)
- Selective sex-related modification of diethylnitrosamine-induced carcinogenesis in BALB/c mice by concomitant administration of butylated hydroxytoluene. Clapp, N.K., Tyndall, R.L., Satterfield, L.C., Klima, W.C., Bowles, N.D. J. Natl. Cancer Inst. (1978)
- Free radical-derived quinone methide mediates skin tumor promotion by butylated hydroxytoluene hydroperoxide: expanded role for electrophiles in multistage carcinogenesis. Guyton, K.Z., Bhan, P., Kuppusamy, P., Zweier, J.L., Trush, M.A., Kensler, T.W. Proc. Natl. Acad. Sci. U.S.A. (1991)
- Oxygen-mediated heterogeneity of apo-low-density lipoprotein. Schuh, J., Fairclough, G.F., Haschemeyer, R.H. Proc. Natl. Acad. Sci. U.S.A. (1978)
- Regulation of nitric oxide production in human coronary microvessels and the contribution of local kinin formation. Kichuk, M.R., Seyedi, N., Zhang, X., Marboe, C.C., Michler, R.E., Addonizio, L.J., Kaley, G., Nasjletti, A., Hintze, T.H. Circulation (1996)
- Genetic ablation of inducible nitric oxide synthase decreases mouse lung tumorigenesis. Kisley, L.R., Barrett, B.S., Bauer, A.K., Dwyer-Nield, L.D., Barthel, B., Meyer, A.M., Thompson, D.C., Malkinson, A.M. Cancer Res. (2002)
- Enhancement of tumor invasion depends on transdifferentiation of skin fibroblasts mediated by reactive oxygen species. Cat, B., Stuhlmann, D., Steinbrenner, H., Alili, L., Holtkötter, O., Sies, H., Brenneisen, P. J. Cell. Sci. (2006)
- The effect of butylated hydroxytoluene on the growth of enzyme-altered foci in male Fischer 344 rat liver tissue. Lok, E., Mehta, R., Jee, P., Laver, G., Nera, E.A., McMullen, E., Clayson, D.B. Carcinogenesis (1995)
- Beta-catenin in the fibroproliferative response to acute lung injury. Douglas, I.S., Diaz del Valle, F., Winn, R.A., Voelkel, N.F. Am. J. Respir. Cell Mol. Biol. (2006)
- Inhibition of 7,12-dimethylbenz(a)anthracene-induced rat mammary carcinogenesis by concomitant or postcarcinogen antioxidant exposure. McCormick, D.L., Major, N., Moon, R.C. Cancer Res. (1984)
- Heart cross-reactive antigens of mutans streptococci share epitopes with group A streptococci and myosin. Ayakawa, G.Y., Bleiweis, A.S., Crowley, P.J., Cunningham, M.W. J. Immunol. (1988)