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Chemical Compound Review

Bromobutane     1-bromobutane

Synonyms: n-Butylbromide, PubChem3752, CCRIS 831, Butyl bromide, CHEMBL160949, ...
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Disease relevance of n-Butylbromide


Psychiatry related information on n-Butylbromide


High impact information on n-Butylbromide


Anatomical context of n-Butylbromide


Associations of n-Butylbromide with other chemical compounds

  • At 295 K, a = 9.378 (2), b = 13.379 (5), c = 10.247 (3) A, beta = 95.93 (3) degrees, V = 1278.8 (7) A3, Dn = 1.346, Dm = 1.348 (1) g cm-3 (in dibromomethane/bromobutane), lambda = 1.1588 (2) A, mu = 2.186 cm-1, F(000) = 176.4 fm, R(F2) = 0.108 for all 1995 nonequivalent reflections with sin theta/lambda less than 0.71 A-1 [7].
  • Surface tensions of the 1-bromobutane with isomeric butanol mixtures were measured in the temperature range 283.15 K (or 298.15 K for 2-methyl-2-propanol) to 313.15 K with a drop volume tensiometer, and the corresponding surface tension deviations were calculated [8].

Gene context of n-Butylbromide


Analytical, diagnostic and therapeutic context of n-Butylbromide

  • CONCLUSIONS: Premedication with intravenous hyoscine n-butyl bromide reduces colonic spasm and in this study made colonoscope insertion significantly quicker and easier [10].
  • BACKGROUND: A prospective, double-blinded, placebo-controlled randomized trial was conducted to investigate the effect of the antispasmodic hyoscine N-butyl bromide (Buscopan) during colonoscopy [11].
  • CONCLUSIONS: Premedication with intravenously administered hyoscine N-butyl bromide impedes colonoscope insertion and causes greater patient discomfort, as well as hemodynamic instability [11].
  • RESULTS: Mean cecal intubation time in the hyoscine N-butyl bromide group was significantly longer than the control group (12.20 vs. 9.74 minutes; p=0.04; but correction for multiple testing of data removed this significance) [11].
  • The possible benefits of premedication with the antispasmodic hyoscine n-butyl bromide (hyoscine) and analgesia with inhaled nitrous oxide/oxygen mixture (nitrous oxide) were assessed in a double-blinded, placebo-controlled trial [12].


  1. A randomized study comparing glucagon and hyoscine N-butyl bromide before endoscopic retrograde cholangiopancreatography. Chang, F.Y., Guo, W.S., Liao, T.M., Lee, S.D. Scand. J. Gastroenterol. (1995) [Pubmed]
  2. Effects of oral cyclotropium bromide, hyoscine N-butylbromide and placebo on gastric emptying and antral motor activity in healthy man. Stacher, G., Bergmann, H., Havlik, E., Schmierer, G., Schneider, C. Gut (1984) [Pubmed]
  3. Electrophoretically mediated microanalysis with partial filling technique and indirect or direct detection as a tool for inhibition studies of enzymatic reaction. Telnarová, M., Vytisková, S., Monincová, M., Glatz, Z. Electrophoresis (2004) [Pubmed]
  4. Effect of hyoscine N-butylbromide on gastroesophageal reflux in normal subjects and patients with gastroesophageal reflux disease. Ciccaglione, A.F., Grossi, L., Cappello, G., Malatesta, M.G., Ferri, A., Toracchio, S., Marzio, L. Am. J. Gastroenterol. (2001) [Pubmed]
  5. Morphine, haloperidol and hyoscine N-butyl bromide combined in s.c. infusion solutions: compatibility and stability. Evaluation in terminal oncology patients. Negro, S., Reyes, R., Azuara, M.L., Sánchez, Y., Barcia, E. International journal of pharmaceutics. (2006) [Pubmed]
  6. Comparison of the isolated human and guinea pig gallbladder strip models in the assessment of antispasmodic drugs. Baistrocchi, R., de los Santos, A.R., Di Girolamo, G., Martí, M.L., Pico, J. Methods and findings in experimental and clinical pharmacology. (1999) [Pubmed]
  7. Structure of the adipate complex [Na2(C6H9O4)2(C6H10O4)].2H2O from neutron diffraction at 220 and 295 K. Gao, Q., Clancy, L., Weber, H.P., Craven, B.M., McMullan, R.K. Acta Crystallogr., B (1991) [Pubmed]
  8. Surface behavior of the 1-bromobutane with isomeric butanol mixtures. Giner, B., Gascón, I., Artigas, H., Royo, F.M., Lafuente, C. The journal of physical chemistry. B, Condensed matter, materials, surfaces, interfaces & biophysical. (2005) [Pubmed]
  9. Compared effect of a genetically engineered glucagon and hyoscine N-butylbromide on double-contrast barium meal study. Cittadini, G., Sardanelli, F., De Cicco, E., Casiglia, M., De Cata, T., Parodi, R.C. European radiology. (1998) [Pubmed]
  10. Premedication with intravenous antispasmodic speeds colonoscope insertion. Saunders, B.P., Williams, C.B. Gastrointest. Endosc. (1996) [Pubmed]
  11. Randomized, double-blinded, placebo-controlled trial of intravenously administered hyoscine N-butyl bromide in patients undergoing colonoscopy with patient-controlled sedation. Mui, L.M., Ng, E.K., Chan, K.C., Ng, C.S., Yeung, A.C., Chan, S.K., Wong, S.K., Chung, S.C. Gastrointest. Endosc. (2004) [Pubmed]
  12. Intravenous antispasmodic and patient-controlled analgesia are of benefit for screening flexible sigmoidoscopy. Saunders, B.P., Elsby, B., Boswell, A.M., Atkin, W., Williams, C.B. Gastrointest. Endosc. (1995) [Pubmed]
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