Disease relevance of 52622-54-5

• The subunit arrangement of the reaction center complex (RC) of Rhodopseudomonas sphaeroides was studied by chemical modification with four different cross-linking reagents using purified RC in lauryldimethylamine oxide, RC incorporated into liposomes, and intact chromatophore membranes, from which RCs are isolated [1].
• Interconversion of high and low adenosinetriphosphatase activity forms of Escherichia coli F1 by the detergent lauryldimethylamine oxide [2].
• Metabolism of dodecyldimethylamine by Pseudomonas MA3 [3].
• N,N-dimethyl-n-dodecylamine caused contact dermatitis [4].
• 1. Reaction centers from Rhodospirillum rubrum have been extracted with the zwitterionic detergent lauryl dimethyl amine oxide [5].

High impact information on 52622-54-5

• The enzyme was solubilized from Golgi vesicles in 5% lauryldimethylamine oxide and "partially" purified by affinity chromatography twice on CMP-hexanolamine and once on lactosylceramide aldehyde-Sepharose 4B [6].
• When assayed in the presence of lauryldimethylamine oxide, which prevents turnover-dependent entrapment of inhibitory MgADP in a catalytic site, ATPase activity of the cross-linked form is 47% that of the unmodified mutant enzyme [7].
• Significantly, and in contrast to the chloroplast and E. coli epsilon subunits, which are readily removed from their parent F1 moieties after treatment respectively with ethanol and lauryldimethylamine oxide, the rat liver delta subunit remained tightly bound to F1 under these relatively mild conditions [8].
• Biopsies of non-palmo-plantar human skin were incubated at 37 degrees C, pH 8, in a buffer with and without additions of detergents (a mixture of N,N-dimethyldodecylamine oxide and sodium dodecyl sulphate), ethylene diamine tetraacetate (EDTA), and the proteinase inhibitor aprotinin [9].
• Like the native F(1)F(o)-ATP synthase, the recombinant TA2F(1) was blocked in ATP hydrolysis activity, and this activity was stimulated by the detergent lauryldimethylamine oxide [10].

Chemical compound and disease context of 52622-54-5

• Degradation of the alkyl chain of dodecyldimethylamine by Pseudomonas MA3 appeared from the stoichiometric liberation of dimethylamine [3].

Anatomical context of 52622-54-5

• Reaction centers from Rhodopseudomonas sphaeroides R 26 have been isolated from a crude extract obtained by lauryldimethylamine oxide extraction of chromatophore membranes, by HPLC using a combination of surface-mediated and size exclusion chromatography [11].
• Transient electric birefringence studies have been made on bovine rhodopsin solubilized in the detergent lauryldimethylamine oxide from glutaraldehyde fixed rod outer segment (ROS) membranes [12].

Associations of 52622-54-5 with other chemical compounds

• A 1H and 13C N.M.R. study of all-trans retinal in dodecyldimethylamine oxide micelles [13].
• Synthesis and characterization of N,N-dimethyldodecylamine-capped Aucore-Pdshell nanoparticles in toluene [14].
• Micellar titrations were also conducted on binary surfactant mixtures containing the pH-sensitive surfactant dodecyldimethylamine oxide (C12DAO) and either the cationic surfactant dodecyltrimethylammonium bromide (C12TAB) or the nonionic surfactant dodecyl octa(ethylene oxide) (C12E8) [15].

Gene context of 52622-54-5

• ATPase assays of F(1)Deltadelta crystals exhibited latent ATP hydrolytic activity that was highly stimulated by lauryldimethylamine oxide, a hallmark of the native enzyme [16].
• Special considerations in the purification of the GM3 ganglioside forming enzyme, CMP-sialic acid:lactosylceramide alpha 2-3 sialyltransferase (SAT-1): solubilization of SAT-1 with lauryldimethylamine oxide [17].

References