Gene Review:
Emx1 - empty spiracles homeobox 1
Mus musculus
Synonyms:
Empty spiracles homolog 1, Empty spiracles-like protein 1, Emx-1, Homeobox protein EMX1
- Nested expression domains of four homeobox genes in developing rostral brain. Simeone, A., Acampora, D., Gulisano, M., Stornaiuolo, A., Boncinelli, E. Nature (1992)
- Emx homeogenes and mouse brain development. Cecchi, C., Boncinelli, E. Trends Neurosci. (2000)
- Ventralized dorsal telencephalic progenitors in Pax6 mutant mice generate GABA interneurons of a lateral ganglionic eminence fate. Kroll, T.T., O'Leary, D.D. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Absence of Cajal-Retzius cells and subplate neurons associated with defects of tangential cell migration from ganglionic eminence in Emx1/2 double mutant cerebral cortex. Shinozaki, K., Miyagi, T., Yoshida, M., Miyata, T., Ogawa, M., Aizawa, S., Suda, Y. Development (2002)
- Expression of the Vax family homeobox genes suggests multiple roles in eye development. Ohsaki, K., Morimitsu, T., Ishida, Y., Kominami, R., Takahashi, N. Genes Cells (1999)
- Emx1 and Emx2 cooperate to regulate cortical size, lamination, neuronal differentiation, development of cortical efferents, and thalamocortical pathfinding. Bishop, K.M., Garel, S., Nakagawa, Y., Rubenstein, J.L., O'Leary, D.D. J. Comp. Neurol. (2003)
- Dorsal telencephalon-specific expression of Cre recombinase in PAC transgenic mice. Iwasato, T., Nomura, R., Ando, R., Ikeda, T., Tanaka, M., Itohara, S. Genesis (2004)
- Emx1, emx2 and pax6 in specification, regionalization and arealization of the cerebral cortex. Muzio, L., Mallamaci, A. Cereb. Cortex (2003)
- The transcription factors Emx1 and Emx2 suppress choroid plexus development and promote neuroepithelial cell fate. von Frowein, J., Wizenmann, A., Götz, M. Dev. Biol. (2006)
- Emx1 and Emx2 functions in development of dorsal telencephalon. Yoshida, M., Suda, Y., Matsuo, I., Miyamoto, N., Takeda, N., Kuratani, S., Aizawa, S. Development (1997)
- Emx1 is a marker for pyramidal neurons of the cerebral cortex. Chan, C.H., Godinho, L.N., Thomaidou, D., Tan, S.S., Gulisano, M., Parnavelas, J.G. Cereb. Cortex (2001)
- Gli3 is required for Emx gene expression during dorsal telencephalon development. Theil, T., Alvarez-Bolado, G., Walter, A., Rüther, U. Development (1999)
- Emx and Otx gene expression in the developing mouse brain. Boncinelli, E., Gulisano, M., Spada, F., Broccoli, V. Ciba Found. Symp. (1995)
- Emx1 and Emx2 show different patterns of expression during proliferation and differentiation of the developing cerebral cortex in the mouse. Gulisano, M., Broccoli, V., Pardini, C., Boncinelli, E. Eur. J. Neurosci. (1996)
- Noggin and basic FGF were implicated in forebrain fate and caudal fate, respectively, of the neural tube-like structures emerging in mouse ES cell culture. Chiba, S., Kurokawa, M.S., Yoshikawa, H., Ikeda, R., Takeno, M., Tadokoro, M., Sekino, H., Hashimoto, T., Suzuki, N. Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale. (2005)
- Expression of the Emx-1 and Dlx-1 homeobox genes define three molecularly distinct domains in the telencephalon of mouse, chick, turtle and frog embryos: implications for the evolution of telencephalic subdivisions in amniotes. Fernandez, A.S., Pieau, C., Repérant, J., Boncinelli, E., Wassef, M. Development (1998)
- Reduced anxiety-- and depression-like behaviors in Emx1 homozygous mutant mice. Cao, B.J., Li, Y. Brain Res. (2002)
- disabled-1 functions cell autonomously during radial migration and cortical layering of pyramidal neurons. Hammond, V., Howell, B., Godinho, L., Tan, S.S. J. Neurosci. (2001)