Gene Review:
Hoxa2 - homeobox A2
Mus musculus
Synonyms:
AI324701, HOX1.11, Homeobox protein Hox-1.11, Homeobox protein Hox-A2, Hox-1.11, ...
- Compensatory defects associated with mutations in Hoxa1 restore normal palatogenesis to Hoxa2 mutants. Barrow, J.R., Capecchi, M.R. Development (1999)
- Segmental expression of Hoxa-2 in the hindbrain is directly regulated by Krox-20. Nonchev, S., Vesque, C., Maconochie, M., Seitanidou, T., Ariza-McNaughton, L., Frain, M., Marshall, H., Sham, M.H., Krumlauf, R., Charnay, P. Development (1996)
- SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation. Dobreva, G., Chahrour, M., Dautzenberg, M., Chirivella, L., Kanzler, B., Fariñas, I., Karsenty, G., Grosschedl, R. Cell (2006)
- Hoxa-2 mutant mice exhibit homeotic transformation of skeletal elements derived from cranial neural crest. Gendron-Maguire, M., Mallo, M., Zhang, M., Gridley, T. Cell (1993)
- A homeotic transformation is generated in the rostral branchial region of the head by disruption of Hoxa-2, which acts as a selector gene. Rijli, F.M., Mark, M., Lakkaraju, S., Dierich, A., Dollé, P., Chambon, P. Cell (1993)
- Hoxa2 and Hoxb2 control dorsoventral patterns of neuronal development in the rostral hindbrain. Davenne, M., Maconochie, M.K., Neun, R., Pattyn, A., Chambon, P., Krumlauf, R., Rijli, F.M. Neuron (1999)
- Temporal and spatial expression of Hoxa-2 during murine palatogenesis. Nazarali, A., Puthucode, R., Leung, V., Wolf, L., Hao, Z., Yeung, J. Cell. Mol. Neurobiol. (2000)
- Temporal requirement of Hoxa2 in cranial neural crest skeletal morphogenesis. Santagati, F., Minoux, M., Ren, S.Y., Rijli, F.M. Development (2005)
- Early stages of oligodendrocyte development in the embryonic murine spinal cord proceed normally in the absence of Hoxa2. Nicolay, D.J., Doucette, J.R., Nazarali, A.J. Glia (2004)
- The little (lit) mutation cosegregates with the growth hormone releasing factor receptor on mouse chromosome 6. Chua, S.C., Hennessey, K., Zeitler, P., Leibel, R.L. Mamm. Genome (1993)
- Roles of Hoxa1 and Hoxa2 in patterning the early hindbrain of the mouse. Barrow, J.R., Stadler, H.S., Capecchi, M.R. Development (2000)
- Coordinated expression of Hoxa2, Hoxd1 and Pax6 in the developing diencephalon. Wolf, L.V., Yeung, J.M., Doucette, J.R., Nazarali, A.J. Neuroreport (2001)
- Reversible gene inactivation in the mouse. Mallo, M., Kanzler, B., Ohnemus, S. Genomics (2003)
- Development of the mammalian ear: coordinate regulation of formation of the tympanic ring and the external acoustic meatus. Mallo, M., Gridley, T. Development (1996)
- The expression pattern of the mouse receptor tyrosine kinase gene MDK1 is conserved through evolution and requires Hoxa-2 for rhombomere-specific expression in mouse embryos. Taneja, R., Thisse, B., Rijli, F.M., Thisse, C., Bouillet, P., Dollé, P., Chambon, P. Dev. Biol. (1996)
- Mesenchymal patterning by Hoxa2 requires blocking Fgf-dependent activation of Ptx1. Bobola, N., Carapuço, M., Ohnemus, S., Kanzler, B., Leibbrandt, A., Neubüser, A., Drouin, J., Mallo, M. Development (2003)
- Hoxa2 downregulates Six2 in the neural crest-derived mesenchyme. Kutejova, E., Engist, B., Mallo, M., Kanzler, B., Bobola, N. Development (2005)
- Ectopic Hoxa-1 induces rhombomere transformation in mouse hindbrain. Zhang, M., Kim, H.J., Marshall, H., Gendron-Maguire, M., Lucas, D.A., Baron, A., Gudas, L.J., Gridley, T., Krumlauf, R., Grippo, J.F. Development (1994)
- Conservation and diversity in the cis-regulatory networks that integrate information controlling expression of Hoxa2 in hindbrain and cranial neural crest cells in vertebrates. Tümpel, S., Maconochie, M., Wiedemann, L.M., Krumlauf, R. Dev. Biol. (2002)
- Six2 functions redundantly immediately downstream of Hoxa2. Kutejova, E., Engist, B., Self, M., Oliver, G., Kirilenko, P., Bobola, N. Development (2008)
- Murine Hox-1.11 homeobox gene structure and expression. Tan, D.P., Ferrante, J., Nazarali, A., Shao, X., Kozak, C.A., Guo, V., Nirenberg, M. Proc. Natl. Acad. Sci. U.S.A. (1992)