The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

ANGEL1  -  angel homolog 1 (Drosophila)

Homo sapiens

Synonyms: Ccr4e, KIAA0759, Protein angel homolog 1
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of ANGEL1

  • Two patients with classical features of Angel-man syndrome (AS) and one with Prader-Willi syndrome (PWS) had unbalanced reciprocal translocations involving the chromosome 15 proximal long arm and the telomeric region of chromosomes 7, 8 and 10 [1].
  • Between 1969-1987, 296 male patients with epidermoid carcinoma of the larynx treated at the Institute of Oncology "Angel H. Roffo" were studied regarding prognostic factors of survival [2].
  • One hundred and ninety-six women with breast cancer admitted to the Institute of Oncology "Angel H. Roffo" and 205 controls were interviewed to obtain information on demographic, socio-economic and reproductive variables, on frequency of consumption of 40 food items, and on methods of cooking [3].
  • CONCLUSIONS: Due to its hallucinogenic effects, abuse of Angel trumpet lily is not uncommon and should be suspected in adolescents presenting with altered mental state and hallucinations in conjunction with other anticholinergic symptoms and signs [4].
  • Total hip arthroplasties were performed to treat the osteoarthrosis on the bilateral hip joint due to Angel-shaped phalango-epiphyseal dysplasia [5].
 

High impact information on ANGEL1

  • Here, Miguel Angel del Pozo and colleagues discuss how these molecules also appear to regulate the redistribution of cell adhesion receptors [6].
  • The result indicates that MMP-3 is identical with stromelysin (Whitham, S. E., Murphy, G., Angel, P., Rahmsdorf, H.-J., Smith, B. J., Lyons, A., Harris, T. J. R., Reynolds, J. J., Herrlich, P., and Docherty, A. J. P. (1986) Biochem. J. 240, 913-916) [7].
  • The clusters contained members of the FLVCR, Angel (KIAA0759), JDP, p21SNFT, and TGF- families, as well as two uncharacterized families [8].
  • The patient underwent transcatheter closure with the Das Angel Wings transcatheter occluder (Microvena Corporation, White Bear Lake, MN) with immediate improvement [9].
  • The H- and M-wave responses to artificial stimulation of the tibial nerve (Angel and Hofmann, 1963) were used to assess spinal cord activation level which constituted the major dependent variable in the study [10].
 

Chemical compound and disease context of ANGEL1

  • In addition to historical background, the devices discussed here include (in alphabetical order) the Amplatzer Septal Occluder, the Atrial Septal Defect Occlusion System, the Buttoned Device, the Guardian Angel (Angel Wings), the Helex Septal Occluder, the StarFlex (Cardioseal, Clamshell), and transcatheter patch closure of atrial septal defects [11].
 

Biological context of ANGEL1

  • This article outlines an inservice developed at Attic Angel Place in Madison, Wisconsin. Using the popular television show Survivors, the facility developed an obstacle course-like survivor training program dealing with accident prevention and bio-hazardous materials [12].
  • PHS Chronicles. The Public Health Service on Angel Island [13].
  • Upstream of the c-jun oncogene is an AP-1 site that can modulate the expression and induction of this gene and is responsive to TPA (Angel et al. 1988) [14].
 

Anatomical context of ANGEL1

  • We studied the effects of Phencyclidine (PCP, Angel Dust) on the developing chick embryo brain [15].
  • The Level 1 and Ranger also efficiently warmed all fluids except cold LR to approximately 37 degrees C. The Thermal Angel generally warmed room temperature fluid, cold Hextend, and packed red blood cells to at least 33 degrees C to 34 degrees C but could not warm cold LR [16].
 

Associations of ANGEL1 with chemical compounds

  • [3H]Phencyclidine (PCP, Angel Dust) receptors have been characterized using a rat brain binding section technique [17].
  • The application of pancuronium bromide (Pavulon) forensic analyses to tissue samples from an "Angel of Death" investigation [18].
  • For approximately five years, the Indiana University School of Medicine has employed Angel as its online teaching environment, and the Ruth Lilly Medical Library has been actively involved in the adoption of Angel [19].
 

Other interactions of ANGEL1

  • As an extension of previous studies (Urbanczyk, Angel, & Kennelly, Brain and Cognition, 8, 206-226) examining the effects of unimanual tapping on lateralized cognitive tasks, lateral body orienting was added to an established dual task paradigm to generate differential hemispheric activation and shifts of attention [20].
 

Analytical, diagnostic and therapeutic context of ANGEL1

  • In this report, we show a 35-year-old female with Angel-shaped phalango-epiphyseal dysplasia that was treated by bilateral total hip arthroplasty [5].
  • The suspect was initially labeled a benevolent Angel of Death who ended the suffering of elderly patients through mercy killing [18].

References

  1. Investigations with fluorescence in situ hybridization (FISH) demonstrate loss of the telomeres on the reciprocal chromosome in three unbalanced translocations involving chromosome 15 in the Prader-Willi and Angelman syndromes. Jauch, A., Robson, L., Smith, A. Hum. Genet. (1995) [Pubmed]
  2. Prognostic factors in laryngeal carcinoma. Experience in 296 male patients. Pradier, R., González, A., Matos, E., Loria, D., Adan, R., Saco, P., Califano, L. Cancer (1993) [Pubmed]
  3. Breast cancer in Argentina: case-control study with special reference to meat eating habits. Matos, E.L., Thomas, D.B., Sobel, N., Vuoto, D. Neoplasma (1991) [Pubmed]
  4. Angel trumpet lily poisoning in five adolescents: clinical findings and management. Francis, P.D., Clarke, C.F. Journal of paediatrics and child health. (1999) [Pubmed]
  5. Total hip arthroplasty for a patient with angel-shaped phalango-epiphyseal dysplasia (ASPED). A case report. Warashina, H., Sakano, S., Kitamura, S., Yamauchi, K., Kito, H., Hasegawa, Y. Nagoya journal of medical science. (2002) [Pubmed]
  6. Cellular polarization induced by chemokines: a mechanism for leukocyte recruitment? del Pozo, M.A., Sanchez-Mateos, P., Sanchez-Madrid, F. Immunol. Today (1996) [Pubmed]
  7. The complete primary structure of human matrix metalloproteinase-3. Identity with stromelysin. Saus, J., Quinones, S., Otani, Y., Nagase, H., Harris, E.D., Kurkinen, M. J. Biol. Chem. (1988) [Pubmed]
  8. Genomic structure and evolutionary context of the human feline leukemia virus subgroup C receptor (hFLVCR) gene: evidence for block duplications and de novo gene formation within duplicons of the hFLVCR locus. Lipovich, L., Hughes, A.L., King, M.C., Abkowitz, J.L., Quigley, J.G. Gene (2002) [Pubmed]
  9. Transcatheter closure of a patent foramen ovale following mitral valve replacement. Skulski, R., Snider, J.M., Buzzard, C.J., Ling, F.S., Mendelsohn, A.M. Ann. Thorac. Surg. (1999) [Pubmed]
  10. Motor neuron excitability: the Hoffmann reflex following exercise of low and high intensity. Bulbulian, R., Darabos, B.L. Medicine and science in sports and exercise. (1986) [Pubmed]
  11. Percutaneous catheter closure of secundum atrial septal defects: a review. Ebeid, M.R. The Journal of invasive cardiology. (2002) [Pubmed]
  12. Survivor training challenge. . . A creative approach to safety education program in a long term care facility. Peterson, R. Director (Cincinnati, Ohio) (2001) [Pubmed]
  13. PHS Chronicles. The Public Health Service on Angel Island. Lucaccini, L.F. Public health reports (Washington, D.C. : 1974) (1996) [Pubmed]
  14. Regulation of immediate early gene expression. Cochran, B.H. NIDA Res. Monogr. (1993) [Pubmed]
  15. Toxic effects of phencyclidine on developing chick embryo brain. Ahmad, G., Zamenhof, S. Life Sci. (1987) [Pubmed]
  16. Evaluation of commercially available fluid-warming devices for use in forward surgical and combat areas. Dubick, M.A., Brooks, D.E., Macaitis, J.M., Bice, T.G., Moreau, A.R., Holcomb, J.B. Military medicine. (2005) [Pubmed]
  17. Properties of the phencyclidine (PCP) receptors. Quirion, R., Pert, C.B. Prog. Neuropsychopharmacol. Biol. Psychiatry (1983) [Pubmed]
  18. The application of pancuronium bromide (Pavulon) forensic analyses to tissue samples from an "Angel of Death" investigation. Andresen, B.D., Alcaraz, A., Grant, P.M. J. Forensic Sci. (2005) [Pubmed]
  19. Angel: post-implementation evaluation at the Indiana University School of Medicine. Hatfield, A.J., Brahmi, F.A. Medical reference services quarterly. (2004) [Pubmed]
  20. The effects of voluntary lateral orienting on positive manifold for lateralized cognitive tasks. Urbanczyk, S.A., Kennelly, K.J. Brain and cognition. (1991) [Pubmed]
 
WikiGenes - Universities