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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Hip Joint

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Disease relevance of Hip Joint

  • In conclusion, when evaluated after 7 days of treatment, the daily addition of codeine 180 mg to paracetamol 3 g significantly reduced the intensity of chronic pain due to osteoarthritis of the hip joint [1].
  • Spondyloepiphyseal dysplasia tarda (SEDL) is a radiologically distinct, X-chromosome linked primary skeletal dysplasia characterised by disproportionate short-trunked short stature, dysplasia of the large joints (hip) and flattened thoracic and lumber vertebral bodies [2].
  • Study II: Ultrasonography was evaluated as a method to identify hip joint synovitis in 76 patients with RA of shorter disease duration, by relating it to radiograms and clinical findings [3].
  • Thus, M-CSF is locally produced in periprosthetic tissues of loose hip joints and possibly contributes to periprosthetic weakening and osteolysis via joint fluid, leading to prosthetic loosening [4].
  • The aim of this study was to investigate the predictive value of CML-Hb in the progression of DRA using computed tomography images of 2-year or 3-year follow-up periods of patients with amyloid bone cysts at the hip joint [5].

Psychiatry related information on Hip Joint


High impact information on Hip Joint


Chemical compound and disease context of Hip Joint


Biological context of Hip Joint


Anatomical context of Hip Joint


Associations of Hip Joint with chemical compounds


Gene context of Hip Joint

  • Gelatin-zymographic analysis confirmed the presence of both pro- and active forms of MMP-2, which suggested the in situ activation of MMP-2 by MT1-MMP in the loose hip joints [32].
  • In loose hip joints, reverse transcription-PCR analysis showed the presence of MT1-MMP, MMP-2, and TIMP-2 mRNA in both the bone-implant interface and regenerating capsular tissues [32].
  • In this paper, we compare DRB1* typing and serum COMP levels in a prospectively observed group of RA patients with or without early hip joint destruction [33].
  • The COMP levels at study inclusion, median 11 months from onset of symptoms, were significantly higher in the patients with early hip joint destruction compared to the patients in the more benign group [33].
  • Protein expression of MMP-13, uPA, and PAI-1 in pseudocapsular and interface tissue around implants of loose artificial hip joints and in osteoarthritis [34].

Analytical, diagnostic and therapeutic context of Hip Joint


  1. Codeine plus paracetamol versus paracetamol in longer-term treatment of chronic pain due to osteoarthritis of the hip. A randomised, double-blind, multi-centre study. Kjaersgaard-Andersen, P., Nafei, A., Skov, O., Madsen, F., Andersen, H.M., Krøner, K., Hvass, I., Gjøderum, O., Pedersen, L., Branebjerg, P.E. Pain (1990) [Pubmed]
  2. Spondyloepiphyseal dysplasia tarda (SEDL, MIM #313400). Savarirayan, R., Thompson, E., Gécz, J. Eur. J. Hum. Genet. (2003) [Pubmed]
  3. Hip involvement in early rheumatoid arthritis. Eberhardt, K., Fex, E., Johnsson, K., Geborek, P. Ann. Rheum. Dis. (1995) [Pubmed]
  4. High macrophage-colony stimulating factor levels in synovial fluid of loose artificial hip joints. Takei, I., Takagi, M., Ida, H., Ogino, T., Santavirta, S., Konttinen, Y.T. J. Rheumatol. (2000) [Pubmed]
  5. Potential value of CML-Hb in predicting the progression of bone cysts in dialysis-related amyloidosis. Motomiya, Y., Iwamoto, H., Uji, Y., Higashi, T., Uchimura, T., Maruyama, I. Nephron (2001) [Pubmed]
  6. Physical activity and self-reported, physician-diagnosed osteoarthritis: is physical activity a risk factor? Cheng, Y., Macera, C.A., Davis, D.R., Ainsworth, B.E., Troped, P.J., Blair, S.N. Journal of clinical epidemiology. (2000) [Pubmed]
  7. Cartilage and bone metabolism in rheumatoid arthritis. Differences between rapid and slow progression of disease identified by serum markers of cartilage metabolism. Månsson, B., Carey, D., Alini, M., Ionescu, M., Rosenberg, L.C., Poole, A.R., Heinegård, D., Saxne, T. J. Clin. Invest. (1995) [Pubmed]
  8. Movement generated by interactions between the dense material at the ends of microtubles and non-actin-containing microfilaments in Sticholonche zanclea. Cachon, J., Cachon, M., Tilney, L.G., Tilney, M.S. J. Cell Biol. (1977) [Pubmed]
  9. Erythropoietin with iron supplementation to prevent allogeneic blood transfusion in total hip joint arthroplasty. A randomized, controlled trial. Feagan, B.G., Wong, C.J., Kirkley, A., Johnston, D.W., Smith, F.C., Whitsitt, P., Wheeler, S.L., Lau, C.Y. Ann. Intern. Med. (2000) [Pubmed]
  10. Autosomal dominant avascular necrosis of femoral head in two Taiwanese pedigrees and linkage to chromosome 12q13. Chen, W.M., Liu, Y.F., Lin, M.W., Chen, I.C., Lin, P.Y., Lin, G.L., Jou, Y.S., Lin, Y.T., Fann, C.S., Wu, J.Y., Hsiao, K.J., Tsai, S.F. Am. J. Hum. Genet. (2004) [Pubmed]
  11. Dominant T-cell-receptor beta chain variable region V beta 14+ clones in juvenile rheumatoid arthritis. Grom, A.A., Thompson, S.D., Luyrink, L., Passo, M., Choi, E., Glass, D.N. Proc. Natl. Acad. Sci. U.S.A. (1993) [Pubmed]
  12. Is there evidence to support the inclusion of viscosupplementation in the treatment paradigm for patients with hip osteoarthritis? Conrozier, T., Vignon, E. Clin. Exp. Rheumatol. (2005) [Pubmed]
  13. Atraumatic removal of a well-fixed porous ingrowth hip prosthesis. McClelland, S.J., James, R.L., Simmons, N. Orthopaedic review. (1986) [Pubmed]
  14. Comparative double blind study of the efficacy and safety of tenoxicam vs. piroxicam in osteoarthritis of knee and hip joints. Adelowo, O.O., Chukwuani, C.M., Grange, J.J., Ojeasebhulo, E.E., Onabowale, B.O. West African journal of medicine. (1998) [Pubmed]
  15. The effect of prophylaxis for thrombosis on heterotopic ossification following total hip joint replacement. Eyb, R., Knahr, K. Archives of orthopaedic and traumatic surgery. Archiv für orthopädische und Unfall-Chirurgie. (1983) [Pubmed]
  16. Bacterial adhesion to bisphosphonate coated hydroxyapatite. Ganguli, A., Steward, C., Butler, S.L., Philips, G.J., Meikle, S.T., Lloyd, A.W., Grant, M.H. Journal of materials science. Materials in medicine. (2005) [Pubmed]
  17. Etretinate-induced heterotopic bone formation about the hip joint. A case report including ultrastructural study. Inoue, K., Imai, S., Iwasaki, A., Egawa, M., Hukuda, S. Clin. Orthop. Relat. Res. (1994) [Pubmed]
  18. Effect of prosthetic mass on swing phase work during above-knee amputee ambulation. Gitter, A., Czerniecki, J., Meinders, M. American journal of physical medicine & rehabilitation / Association of Academic Physiatrists. (1997) [Pubmed]
  19. Total hip joint arthroplasty with gentamicin-impregnated cement. A clinical study of gentamicin excretion kinetics. Törholm, C., Lidgren, L., Lindberg, L., Kahlmeter, G. Clin. Orthop. Relat. Res. (1983) [Pubmed]
  20. The painful hip: evaluation of criteria for clinical decision-making. Eich, G.F., Superti-Furga, A., Umbricht, F.S., Willi, U.V. Eur. J. Pediatr. (1999) [Pubmed]
  21. Rapidly destructive arthropathy of the hip. Studies on bone resorptive factors in joint fluid with a theory of pathogenesis. Komiya, S., Inoue, A., Sasaguri, Y., Minamitani, K., Morimatsu, M. Clin. Orthop. Relat. Res. (1992) [Pubmed]
  22. Identification of inducible nitric oxide synthase in human macrophages surrounding loosened hip prostheses. Watkins, S.C., Macaulay, W., Turner, D., Kang, R., Rubash, H.E., Evans, C.H. Am. J. Pathol. (1997) [Pubmed]
  23. Amyloid in osteoarthritic hip joints: deposits in relation to chondromatosis, pyrophosphate, and inflammatory cell infiltrate in the synovial membrane and fibrous capsule. Ladefoged, C. Ann. Rheum. Dis. (1983) [Pubmed]
  24. Comparison of standard and individually planned infradiaphragmatic fields in irradiation of retroperitoneal lymph nodes. Nevinny-Stickel, M., Ennemoser, S., Sweeney, R., Bangerl, I., Zur Nedden, D., Lukas, P. Int. J. Radiat. Oncol. Biol. Phys. (2000) [Pubmed]
  25. Serum cartilage oligomeric matrix protein and clinical signs and symptoms of potential pre-radiographic hip and knee pathology. Dragomir, A.D., Kraus, V.B., Renner, J.B., Luta, G., Clark, A., Vilim, V., Hochberg, M.C., Helmick, C.G., Jordan, J.M. Osteoarthr. Cartil. (2002) [Pubmed]
  26. Subcutaneous deposition of beta 2-microglobulin amyloid in a long-term haemodialysis patient. Athanasou, N.A., Chaplin, A.J., Oliver, D.O. Nephrol. Dial. Transplant. (1990) [Pubmed]
  27. Release of gentamicin from acrylic bone cement. Bunetel, L., Segui, A., Cormier, M., Percheron, E., Langlais, F. Clinical pharmacokinetics. (1989) [Pubmed]
  28. The adult hip: an anatomic study. Part II: the soft-tissue landmarks. Guerra, J., Armbuster, T.G., Resnick, D., Goergen, T.G., Feingold, M.L., Niwayama, G., Danzig, L.A. Radiology. (1978) [Pubmed]
  29. Cemented total hip prosthesis: radiographic and scintigraphic evaluation. Aliabadi, P., Tumeh, S.S., Weissman, B.N., McNeil, B.J. Radiology. (1989) [Pubmed]
  30. A role for hip position in initiating the swing-to-stance transition in walking cats. McVea, D.A., Donelan, J.M., Tachibana, A., Pearson, K.G. J. Neurophysiol. (2005) [Pubmed]
  31. Dose response of intravenous heparin on markers of thrombosis during primary total hip replacement. Sharrock, N.E., Go, G., Sculco, T.P., Salvati, E.A., Westrich, G.H., Harpel, P.C. Anesthesiology (1999) [Pubmed]
  32. The membrane-type-matrix metalloproteinase/matrix metalloproteinase-2/tissue inhibitor of metalloproteinase-2 system in periprosthetic connective-tissue remodeling in loose total-hip prostheses. Takagi, M., Santavirta, S., Ida, H., Ishii, M., Akimoto, K., Saotome, K., Konttinen, Y.T. Lab. Invest. (1998) [Pubmed]
  33. HLA DRB1* typing and cartilage oligomeric matrix protein (COMP) as predictors of joint destruction in recent-onset rheumatoid arthritis. Wollheim, F.A., Eberhardt, K.B., Johnson, U., Saxne, T. Br. J. Rheumatol. (1997) [Pubmed]
  34. Protein expression of MMP-13, uPA, and PAI-1 in pseudocapsular and interface tissue around implants of loose artificial hip joints and in osteoarthritis. Diehl, P., Hantke, B., Hennig, M., Tschesche, H., Mittelmeier, W., Schmitt, M., Muehlenweg, B. Int. J. Mol. Med. (2004) [Pubmed]
  35. Paw-shake responses with joint immobilization: EMG changes with atypical feedback. Koshland, G.F., Smith, J.L. Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale. (1989) [Pubmed]
  36. Candida parapsilosis infection of a total hip-joint replacement: successful reimplantation after treatment with amphotericin B and 5-fluorocytosine. A case report. Younkin, S., Evarts, C.M., Steigbigel, R.T. The Journal of bone and joint surgery. American volume. (1984) [Pubmed]
  37. Controlled hypotension in hip joint surgery. An assessment of surgical haemorrhage during sodium nitroprusside infusion. Vazeery, A.K., Lunde, O. Acta orthopaedica Scandinavica. (1979) [Pubmed]
  38. The role of synovial fluid filtration by cartilage in lubrication of synovial joints--II. Squeeze-film lubrication: homogeneous filtration. Hlavácek, M. Journal of biomechanics. (1993) [Pubmed]
  39. Wear of polyethylene acetabular cups against alumina femoral heads. 5 prostheses compared in a hip simulator for 35 million walking cycles. Saikko, V.O. Acta orthopaedica Scandinavica. (1993) [Pubmed]
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