Gene Review:
HARS2 - histidyl-tRNA synthetase 2, mitochondrial
Homo sapiens
Synonyms:
HARSL, HARSR, HO3, HisRS, Histidine--tRNA ligase-like, ...
- The tRNA-binding moiety in GCN2 contains a dimerization domain that interacts with the kinase domain and is required for tRNA binding and kinase activation. Qiu, H., Dong, J., Hu, C., Francklyn, C.S., Hinnebusch, A.G. EMBO J. (2001)
- Human immunodeficiency virus type 1 matrix protein interacts with cellular protein HO3. Lama, J., Trono, D. J. Virol. (1998)
- Proteobacterial histidine-biosynthetic pathways are paraphyletic. Bond, J.P., Francklyn, C. J. Mol. Evol. (2000)
- Mutations that bypass tRNA binding activate the intrinsically defective kinase domain in GCN2. Qiu, H., Hu, C., Dong, J., Hinnebusch, A.G. Genes Dev. (2002)
- Histidyl-tRNA synthetase and asparaginyl-tRNA synthetase, autoantigens in myositis, activate chemokine receptors on T lymphocytes and immature dendritic cells. Howard, O.M., Dong, H.F., Yang, D., Raben, N., Nagaraju, K., Rosen, A., Casciola-Rosen, L., Härtlein, M., Kron, M., Yang, D., Yiadom, K., Dwivedi, S., Plotz, P.H., Oppenheim, J.J. J. Exp. Med. (2002)
- Activation of the hetero-octameric ATP phosphoribosyl transferase through subunit interface rearrangement by a tRNA synthetase paralog. Champagne, K.S., Sissler, M., Larrabee, Y., Doublié, S., Francklyn, C.S. J. Biol. Chem. (2005)
- Hydrogen isotope effects and mechanism of aqueous ozone and peroxone decompositions. Lesko, T.M., Colussi, A.J., Hoffmann, M.R. J. Am. Chem. Soc. (2004)
- Genomic organization, transcriptional mapping, and evolutionary implications of the human bi-directional histidyl-tRNA synthetase locus (HARS/HARSL). O'Hanlon, T.P., Miller, F.W. Biochem. Biophys. Res. Commun. (2002)
- A novel gene oriented in a head-to-head configuration with the human histidyl-tRNA synthetase (HRS) gene encodes an mRNA that predicts a polypeptide homologous to HRS. O'Hanlon, T.P., Raben, N., Miller, F.W. Biochem. Biophys. Res. Commun. (1995)
- Intracellular localization of histidyl-tRNA synthetase/Jo-1 antigen in T24 cells and some other cells. Kamei, H. J. Autoimmun. (2004)
- Histidyl-tRNA synthetase. Freist, W., Verhey, J.F., Rühlmann, A., Gauss, D.H., Arnez, J.G. Biol. Chem. (1999)
- A substrate-assisted concerted mechanism for aminoacylation by a class II aminoacyl-tRNA synthetase. Guth, E., Connolly, S.H., Bovee, M., Francklyn, C.S. Biochemistry (2005)
- Infrared detection of HO2 and HO3 radicals in water ice. Cooper, P.D., Moore, M.H., Hudson, R.L. The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment & general theory. (2006)