Gene Review:
TMEM158 - transmembrane protein 158 (gene/pseudogene)
Homo sapiens
Synonyms:
40 kDa BINP-binding protein, BBP, HBBP, RIS1, Ras-induced senescence protein 1, ...
- RIS1, a gene with trinucleotide repeats, is a target in the mutator pathway of colorectal carcinogenesis. Iglesias, D., Fernández-Peralta, A.M., Nejda, N., Daimiel, L., Azcoita, M.M., Oliart, S., González-Aguilera, J.J. Cancer Genet. Cytogenet. (2006)
- A retinoic acid-inducible skin-specific gene (RIS-1/psoriasin): molecular cloning and analysis of gene expression in human skin in vivo and cultured skin cells in vitro. Tavakkol, A., Zouboulis, C.C., Duell, E.A., Voorhees, J.J. Mol. Biol. Rep. (1994)
- Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis. Sharpless, N.E., Bardeesy, N., Lee, K.H., Carrasco, D., Castrillon, D.H., Aguirre, A.J., Wu, E.A., Horner, J.W., DePinho, R.A. Nature (2001)
- A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence. Peeper, D.S., Shvarts, A., Brummelkamp, T., Douma, S., Koh, E.Y., Daley, G.Q., Bernards, R. Nat. Cell Biol. (2002)
- INK4a-deficient human diploid fibroblasts are resistant to RAS-induced senescence. Brookes, S., Rowe, J., Ruas, M., Llanos, S., Clark, P.A., Lomax, M., James, M.C., Vatcheva, R., Bates, S., Vousden, K.H., Parry, D., Gruis, N., Smit, N., Bergman, W., Peters, G. EMBO J. (2002)
- Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence. Wang, W., Chen, J.X., Liao, R., Deng, Q., Zhou, J.J., Huang, S., Sun, P. Mol. Cell. Biol. (2002)
- Stepwise neoplastic transformation of a telomerase immortalized fibroblast cell line. Zongaro, S., de Stanchina, E., Colombo, T., D'Incalci, M., Giulotto, E., Mondello, C. Cancer Res. (2005)
- Identification of a candidate tumor-suppressor gene specifically activated during Ras-induced senescence. Barradas, M., Gonos, E.S., Zebedee, Z., Kolettas, E., Petropoulou, C., Delgado, M.D., León, J., Hara, E., Serrano, M. Exp. Cell Res. (2002)
- Specific interaction of PML bodies with the TP53 locus in Jurkat interphase nuclei. Sun, Y., Durrin, L.K., Krontiris, T.G. Genomics (2003)
- Identification and molecular cloning of a novel brain-specific receptor protein that binds to brain injury-derived neurotrophic peptide. Possible role for neuronal survival. Hama, T., Maruyama, M., Katoh-Semba, R., Takizawa, M., Iwashima, M., Nara, K. J. Biol. Chem. (2001)
- Target genes of the WNT/beta-catenin pathway in Wilms tumors. Zirn, B., Samans, B., Wittmann, S., Pietsch, T., Leuschner, I., Graf, N., Gessler, M. Genes Chromosomes Cancer (2006)
- Topical all-trans retinoic acid (RA) induces an early, coordinated increase in RA-inducible skin-specific gene/psoriasin and cellular RA-binding protein II mRNA levels which precedes skin erythema. Zouboulis, C.C., Voorhees, J.J., Orfanos, C.E., Tavakkol, A. Arch. Dermatol. Res. (1996)